Adult | Age
Item
adult patients, >=18 years of age;
boolean
C0001675 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Non-Small Cell Lung Carcinoma Advanced TNM clinical staging
Item
advanced (stage iiib/iv) non-small-cell lung cancer;
boolean
C0007131 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C3258246 (UMLS CUI [1,3])
TNM clinical staging | Contraindication to surgery
Item
although stageⅰ-ⅲa, have contraindications to surgery;
boolean
C3258246 (UMLS CUI [1])
C0852649 (UMLS CUI [2])
EGFR gene mutation Positive | EGFR Exon 18 Mutation Positive | EGFR Exon 19 Mutation Positive | EGFR Exon 21 Mutation Positive
Item
egfr mutation-positive (egfr exon-18, exon-19 or exon-21);
boolean
C3266992 (UMLS CUI [1,1])
C1514241 (UMLS CUI [1,2])
C4289658 (UMLS CUI [2,1])
C1514241 (UMLS CUI [2,2])
C4289656 (UMLS CUI [3,1])
C1514241 (UMLS CUI [3,2])
C4289654 (UMLS CUI [4,1])
C1514241 (UMLS CUI [4,2])
Measurable Disease
Item
measurable disease;
boolean
C1513041 (UMLS CUI [1])
ECOG performance status
Item
ecog performance status 0 or 1 or 2.
boolean
C1520224 (UMLS CUI [1])
EGFR Wild Type
Item
wild-type egfr;
boolean
C1414313 (UMLS CUI [1,1])
C1883559 (UMLS CUI [1,2])
Targeted Therapy HER Family Receptors
Item
prior exposure to agents directed at the her axis;
boolean
C2985566 (UMLS CUI [1,1])
C3812393 (UMLS CUI [1,2])
Prior Chemotherapy | Cancer treatment Systemic | Status post Advanced disease
Item
prior chemotherapy or systemic anti-tumor therapy after advanced disease;
boolean
C1514457 (UMLS CUI [1])
C0920425 (UMLS CUI [2,1])
C0205373 (UMLS CUI [2,2])
C0231290 (UMLS CUI [3,1])
C0679246 (UMLS CUI [3,2])
Systemic disease Unstable
Item
unstable systemic disease;
boolean
C0442893 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])
Cancer Other | Exception Basal cell carcinoma Cured | Exception Carcinoma in situ of uterine cervix Cured
Item
any other malignancy within last 5 years, except cured basal cell cancer of skin or cured cancer in situ of cervix;
boolean
C1707251 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
C1880198 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C0851140 (UMLS CUI [3,2])
C1880198 (UMLS CUI [3,3])
Metastatic malignant neoplasm to brain | Compression of spinal cord
Item
brain metastasis or spinal cord compression.
boolean
C0220650 (UMLS CUI [1])
C0037926 (UMLS CUI [2])