Gender | Childbearing Potential Contraceptive methods
Item
women and men are eligible. women of reproductive age should apply effective contraception.
boolean
C0079399 (UMLS CUI [1])
C3831118 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
Age
Item
age ranges from 20 years (inclusive) to less than 70 years.
boolean
C0001779 (UMLS CUI [1])
Essential Hypertension
Item
patients should have essential hypertension.
boolean
C0085580 (UMLS CUI [1])
Refractory hypertension | Pharmacotherapy Stable | Antihypertensive Agents Quantity | Antihypertensive Agents Class Different | Diuretic
Item
treatment-resistant hypertension in patients taking a stable drug regimen for at least 4 weeks consisting of 3 or more antihypertensive medications from different classes, including a diuretic.
boolean
C0860493 (UMLS CUI [1])
C0013216 (UMLS CUI [2,1])
C0205360 (UMLS CUI [2,2])
C0003364 (UMLS CUI [3,1])
C1265611 (UMLS CUI [3,2])
C0003364 (UMLS CUI [4,1])
C0456387 (UMLS CUI [4,2])
C1705242 (UMLS CUI [4,3])
C0012798 (UMLS CUI [5])
Therapeutic procedure Maximal | Office Blood pressure determination | 24-hour ambulatory blood pressure Systolic | 24-hour ambulatory blood pressure Diastolic
Item
under maximal therapy, office blood pressure should be ≥140/90 mmhg and the 24-h ambulatory blood pressure should be 130 mm hg systolic or 80 mm hg diastolic or higher.
boolean
C0087111 (UMLS CUI [1,1])
C0205289 (UMLS CUI [1,2])
C0442603 (UMLS CUI [2,1])
C0005824 (UMLS CUI [2,2])
C2022220 (UMLS CUI [3,1])
C0039155 (UMLS CUI [3,2])
C2022220 (UMLS CUI [4,1])
C0012000 (UMLS CUI [4,2])
Estimated Glomerular Filtration Rate
Item
egfr must be ≥ 60 ml/min/1.73 m2.
boolean
C3811844 (UMLS CUI [1])
Compliance behavior
Item
the patients should accept to have adherence checked before randomisation and during supervised follow-up, but both patients and doctors will remain blinded to the results;
boolean
C1321605 (UMLS CUI [1])
Informed Consent
Item
informed written consent.
boolean
C0021430 (UMLS CUI [1])
Contextual factors Clinical Suboptimal | Medical History | Comorbidity
Item
suboptimal clinical context, because of recent history or concurrent disease.
boolean
C0542559 (UMLS CUI [1,1])
C0205210 (UMLS CUI [1,2])
C2984009 (UMLS CUI [1,3])
C0262926 (UMLS CUI [2])
C0009488 (UMLS CUI [3])
Isolated systolic hypertension | Diastolic hypertension Isolated
Item
isolated systolic and diastolic hypertension.
boolean
C0745133 (UMLS CUI [1])
C0235222 (UMLS CUI [2,1])
C0205409 (UMLS CUI [2,2])
Body mass index
Item
body-mass index ≥ 40kg/m2.
boolean
C1305855 (UMLS CUI [1])
Anatomy of renal artery Suboptimal Renal artery denervation
Item
the anatomy of the renal arteries is suboptimal for renal denervation.
boolean
C0700276 (UMLS CUI [1,1])
C0035065 (UMLS CUI [1,2])
C2984009 (UMLS CUI [1,3])
C3544270 (UMLS CUI [1,4])
Pregnancy
Item
pregnancy.
boolean
C0032961 (UMLS CUI [1])
Substance Use Disorders | Mental disorders
Item
alcohol or substance abuse or psychiatric illnesses.
boolean
C0038586 (UMLS CUI [1])
C0004936 (UMLS CUI [2])
Study Subject Participation Status
Item
participation in other study.
boolean
C2348568 (UMLS CUI [1])
Contextual factors Clinical Suboptimal Renal artery denervation
Item
the clinical context is suboptimal for renal denervation.
boolean
C0542559 (UMLS CUI [1,1])
C0205210 (UMLS CUI [1,2])
C2984009 (UMLS CUI [1,3])
C3544270 (UMLS CUI [1,4])