Non-Insulin-Dependent Diabetes Mellitus Disease length | Metformin Dose Stable U/day | Combined Modality Therapy | Dipeptidyl Peptidase-4 Inhibitor Dose Stable Daily | Hemoglobin A1c measurement
Item
must have a diagnosis of t2dm for at least 3 months and be on either metformin monotherapy at a stable dose of >=1,000 mg per day or on combination therapy of metformin >=1,000 mg per day and a dpp-4 inhibitor at stable daily doses for at least 12 weeks prior to screening with an hba1c of >=7.0% and <= 9.5% at screening
boolean
C0011860 (UMLS CUI [1,1])
C0872146 (UMLS CUI [1,2])
C0025598 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0205360 (UMLS CUI [2,3])
C0456683 (UMLS CUI [2,4])
C0009429 (UMLS CUI [3])
C3537225 (UMLS CUI [4,1])
C0178602 (UMLS CUI [4,2])
C0205360 (UMLS CUI [4,3])
C0332173 (UMLS CUI [4,4])
C0474680 (UMLS CUI [5])
Plasma fasting glucose measurement
Item
fasting plasma glucose >=120 mg/dl and <=240 mg/dl at the week -4 visit
boolean
C0583513 (UMLS CUI [1])
Fasting fingerstick blood glucose measurement
Item
fasting fingerstick glucose >=120 mg/dl and <=240 mg/dl performed at clinical research center on day -14
boolean
C2317664 (UMLS CUI [1])
Stable status Medical Laboratory Procedures
Item
must be medically stable on the basis of clinical laboratory tests performed at screening
boolean
C0205360 (UMLS CUI [1,1])
C0205476 (UMLS CUI [1,2])
C0022885 (UMLS CUI [1,3])
Diabetic Ketoacidosis | Diabetes Mellitus, Insulin-Dependent | Pancreas Transplantation
Item
has a history of diabetic ketoacidosis, type 1 diabetes mellitus (t1dm), pancreas or
boolean
C0011880 (UMLS CUI [1])
C0011854 (UMLS CUI [2])
C0030275 (UMLS CUI [3])
Pancreatic beta cell Transplantation | Diabetes Mellitus Secondary to Pancreatitis | Diabetes Mellitus Secondary to Pancreatectomy
Item
β-cell transplantation, or diabetes secondary to pancreatitis or pancreatectomy
boolean
C0030281 (UMLS CUI [1,1])
C0040732 (UMLS CUI [1,2])
C0011849 (UMLS CUI [2,1])
C0175668 (UMLS CUI [2,2])
C0030305 (UMLS CUI [2,3])
C0011849 (UMLS CUI [3,1])
C0175668 (UMLS CUI [3,2])
C0030279 (UMLS CUI [3,3])
Claustrophobia | Anxiety Relationship Magnetic Resonance Imaging | Anti-Anxiety Agents Unsuccessful
Item
has claustrophobia or anxiety, related to previous negative experiences with magnetic resonance imaging procedures which cannot be managed with an anxiolytic drug
boolean
C0008909 (UMLS CUI [1])
C0003467 (UMLS CUI [2,1])
C0439849 (UMLS CUI [2,2])
C0024485 (UMLS CUI [2,3])
C0040616 (UMLS CUI [3,1])
C1272705 (UMLS CUI [3,2])
Brittle diabetes | Poor glycemic control | Glucose measurement variant
Item
has a history of brittle or labile glycemic control, with widely varying glucose measurements
boolean
C0342302 (UMLS CUI [1])
C0342299 (UMLS CUI [2])
C0337438 (UMLS CUI [3,1])
C0205419 (UMLS CUI [3,2])
Proliferative diabetic retinopathy Eye examination | Therapeutic procedure Proliferative diabetic retinopathy | Treatment required for Proliferative diabetic retinopathy
Item
has proliferative diabetic retinopathy (based on an eye examination within one year prior to screening), currently receiving or requiring treatment
boolean
C0154830 (UMLS CUI [1,1])
C0200149 (UMLS CUI [1,2])
C0087111 (UMLS CUI [2,1])
C0154830 (UMLS CUI [2,2])
C0332121 (UMLS CUI [3,1])
C0154830 (UMLS CUI [3,2])
Hypoglycaemic episode Severe Quantity
Item
has a history of 1 or more severe hypoglycemic episodes within 6 months before screening
boolean
C0745153 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
Glucose-galactose malabsorption Hereditary | Renal Glycosuria Primary
Item
has history of hereditary glucose-galactose malabsorption or primary renal glucosuria.
boolean
C0268186 (UMLS CUI [1,1])
C0439660 (UMLS CUI [1,2])
C0017980 (UMLS CUI [2,1])
C0205225 (UMLS CUI [2,2])