Age | Gender
Item
age: 18-65 years old, female
boolean
C0001779 (UMLS CUI [1])
C0079399 (UMLS CUI [2])
Adenocarcinoma Invasive
Item
histologically confirmed diagnosis of invasive adenocarcinoma
boolean
C0001418 (UMLS CUI [1,1])
C0205281 (UMLS CUI [1,2])
taxane | Chemotherapy cycle Adjuvant Quantity
Item
intends to receive at least 4 cycles taxanes-based adjuvant chemotherapy
boolean
C0215136 (UMLS CUI [1])
C1302181 (UMLS CUI [2,1])
C1522673 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
Peripheral Neuropathy CTCAE Grades
Item
prior any level of peripheral nerve system disease
boolean
C0031117 (UMLS CUI [1,1])
C1516728 (UMLS CUI [1,2])
Neurotoxicity Questionnaire Completion
Item
with the capability to accurately record the occurrence and severity of neurotoxicity by questionnaire
boolean
C0235032 (UMLS CUI [1,1])
C0034394 (UMLS CUI [1,2])
C0205197 (UMLS CUI [1,3])
Organ Major Function
Item
with normal functions of major organs
boolean
C0178784 (UMLS CUI [1,1])
C0205164 (UMLS CUI [1,2])
C0031843 (UMLS CUI [1,3])
Medical contraindication Absent Chemotherapy
Item
no contraindication to chemotherapy
boolean
C1301624 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0392920 (UMLS CUI [1,3])
Informed Consent
Item
patients have provided a signed informed consent form
boolean
C0021430 (UMLS CUI [1])
Adjuvant Chemotherapy Completion Unlikely
Item
patients are expected not be able to complete adjuvant chemotherapy
boolean
C0085533 (UMLS CUI [1,1])
C0205197 (UMLS CUI [1,2])
C0750558 (UMLS CUI [1,3])
Hypersensitivity GM1
Item
be allergic to gm1
boolean
C0020517 (UMLS CUI [1,1])
C0016895 (UMLS CUI [1,2])
Glucose metabolism abnormal Hereditary | Lipid Metabolism Abnormal Hereditary
Item
hereditary abnormal metabolism of glucose and lipid
boolean
C1142273 (UMLS CUI [1,1])
C0439660 (UMLS CUI [1,2])
C0598783 (UMLS CUI [2,1])
C0205161 (UMLS CUI [2,2])
C0439660 (UMLS CUI [2,3])
Patients Inappropriate GM1 Therapy
Item
doctors believe that patients are not suitable for receiving gm1 treatment
boolean
C0030705 (UMLS CUI [1,1])
C1548788 (UMLS CUI [1,2])
C0016895 (UMLS CUI [1,3])
C0087111 (UMLS CUI [1,4])
Nervous system disorder | Mental disorders | Epilepsy | Dementia
Item
with confirmed history of neurological or psychiatric disorders, including epilepsy and dementia
boolean
C0027765 (UMLS CUI [1])
C0004936 (UMLS CUI [2])
C0014544 (UMLS CUI [3])
C0497327 (UMLS CUI [4])
Comorbidity Affecting Patient safety | Comorbidity Impact Completion of clinical trial
Item
with concomitant diseases that will seriously harm the patients' safety or impact the completion of the study
boolean
C0009488 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C1113679 (UMLS CUI [1,3])
C0009488 (UMLS CUI [2,1])
C4049986 (UMLS CUI [2,2])
C2732579 (UMLS CUI [2,3])
Childbearing Potential Contraceptive methods Unwilling | Childbearing Potential Contraceptive methods Unable
Item
patients have fertility possibility but not willing or not to take effective contraceptive measures
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C0558080 (UMLS CUI [1,3])
C3831118 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
C1299582 (UMLS CUI [2,3])