Inclusion criteria Breast Carcinoma
Item
eligibility criteria for breast cancer cases
boolean
C1512693 (UMLS CUI [1,1])
C0678222 (UMLS CUI [1,2])
Gender | Client Characteristics MRI
Item
women with the following characteristics at mri will be eligible as cases:
boolean
C0079399 (UMLS CUI [1])
C0815172 (UMLS CUI [2,1])
C0024485 (UMLS CUI [2,2])
Invasive carcinoma of breast Unilateral
Item
1. have a newly diagnosed invasive unilateral breast cancer;
boolean
C0853879 (UMLS CUI [1,1])
C0205092 (UMLS CUI [1,2])
MRI Preoperative | MRI Before Therapeutic procedure
Item
2. have a pre-surgical, pre-treatment mri available from the study site;
boolean
C0024485 (UMLS CUI [1,1])
C0445204 (UMLS CUI [1,2])
C0024485 (UMLS CUI [2,1])
C0332152 (UMLS CUI [2,2])
C0087111 (UMLS CUI [2,3])
Age
Item
3. <70 years old at time of diagnosis; and
boolean
C0001779 (UMLS CUI [1])
Breast Contralateral Intact | MRI Breast Intact
Item
4. have an intact contralateral breast. the contralateral breast needs to be intact so mri reading can be done on the breast without cancer. women with a history of previous cancer diagnosis are excluded because treatment they may have received for these cancers might affect the mri readings.
boolean
C0006141 (UMLS CUI [1,1])
C0441988 (UMLS CUI [1,2])
C0205266 (UMLS CUI [1,3])
C0024485 (UMLS CUI [2,1])
C0006141 (UMLS CUI [2,2])
C0205266 (UMLS CUI [2,3])
Inclusion criteria Control Group | Gender | High risk of Breast Carcinoma | Lifetime Risk Percentage Breast Carcinoma
Item
eligibility criteria for controls controls will be women determined to be at high risk of developing breast cancer (i.e., lifetime risk ≥20%).30
boolean
C1512693 (UMLS CUI [1,1])
C0009932 (UMLS CUI [1,2])
C0079399 (UMLS CUI [2])
C0332167 (UMLS CUI [3,1])
C0678222 (UMLS CUI [3,2])
C1517878 (UMLS CUI [4,1])
C0439165 (UMLS CUI [4,2])
C0678222 (UMLS CUI [4,3])
Criteria Fulfill
Item
in addition, they must meet the following criteria:
boolean
C0243161 (UMLS CUI [1,1])
C1550543 (UMLS CUI [1,2])
Magnetic resonance imaging of breast
Item
1. undergoing breast mri screening at one of the three study sites;
boolean
C0344104 (UMLS CUI [1])
Age
Item
2. <70 years old at time of mri; and
boolean
C0001779 (UMLS CUI [1])
Magnetic resonance imaging of breast Negative
Item
3. negative breast mri screen.
boolean
C0344104 (UMLS CUI [1,1])
C1513916 (UMLS CUI [1,2])
Exclusion Criteria Study Subject | Exclusion Criteria Control Group
Item
for either cases or controls:
boolean
C0680251 (UMLS CUI [1,1])
C0681850 (UMLS CUI [1,2])
C0680251 (UMLS CUI [2,1])
C0009932 (UMLS CUI [2,2])
Lacking Able to speak English Language | Lacking Able to read English Language
Item
1. unable to speak and read english;
boolean
C0332268 (UMLS CUI [1,1])
C0564215 (UMLS CUI [1,2])
C0376245 (UMLS CUI [1,3])
C0332268 (UMLS CUI [2,1])
C0586740 (UMLS CUI [2,2])
C0376245 (UMLS CUI [2,3])
Prophylactic Mastectomy
Item
2. history of prophylactic mastectomy;
boolean
C2191320 (UMLS CUI [1])
Breast implants
Item
3. history of pre-pectoral breast implants in either breast (sub-pectoral are acceptable);
boolean
C0179412 (UMLS CUI [1])
Reduction mammaplasty
Item
4. history of breast reduction surgery;
boolean
C0191922 (UMLS CUI [1])
Pharmaceutical Preparations Hormonal | Tamoxifen | Nolvadex | Raloxifene | Evista | Aromatase Inhibitors | anastrozole | Arimidex | letrozole | Femara | exemestane | Aromasin | Hormone Therapy Postmenopausal | Fertility Agents Hormonal
Item
5. currently taking, or in the previous 3 months: hormonal medication such as tamoxifen (nolvadex), raloxifene (evista), aromatase inhibitors (anastrozole/arimidex, letrozole/femara, and/or exemestane/aromasin); and/or other postmenopausal hormonal therapy (pht) medication; and/or hormonal medication for fertility treatment;
boolean
C0013227 (UMLS CUI [1,1])
C0458083 (UMLS CUI [1,2])
C0039286 (UMLS CUI [2])
C0919390 (UMLS CUI [3])
C0244404 (UMLS CUI [4])
C0720318 (UMLS CUI [5])
C0593802 (UMLS CUI [6])
C0290883 (UMLS CUI [7])
C0878174 (UMLS CUI [8])
C0246421 (UMLS CUI [9])
C0701348 (UMLS CUI [10])
C0851344 (UMLS CUI [11])
C0876723 (UMLS CUI [12])
C0279025 (UMLS CUI [13,1])
C0232970 (UMLS CUI [13,2])
C0015896 (UMLS CUI [14,1])
C0458083 (UMLS CUI [14,2])
Pregnancy | Breast Feeding
Item
6. currently, or in the preceding 6 months, pregnant or breast feeding; and
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Malignant Neoplasms Previous | DCIS | Exception Skin carcinoma | Exception Carcinoma in situ of uterine cervix
Item
7. history of previous cancer, including ductal carcinoma in situ (dcis) (nonmelanoma skin cancer and cervical cancer in situ are acceptable).
boolean
C0006826 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
C0007124 (UMLS CUI [2])
C1705847 (UMLS CUI [3,1])
C0699893 (UMLS CUI [3,2])
C1705847 (UMLS CUI [4,1])
C0851140 (UMLS CUI [4,2])