Breast Carcinoma TNM Breast tumor staging | Chemotherapy Neoadjuvant Planned
Item
stage iia-iiic breast cancer patients plan to receive neoadjuvant chemotherapy
boolean
C0678222 (UMLS CUI [1,1])
C0474926 (UMLS CUI [1,2])
C0392920 (UMLS CUI [2,1])
C0600558 (UMLS CUI [2,2])
C1301732 (UMLS CUI [2,3])
Tissue specimen Available Immunohistochemistry
Item
patients have enough tissue sample to do ihc test for subtype classification
boolean
C1292533 (UMLS CUI [1,1])
C0470187 (UMLS CUI [1,2])
C0021044 (UMLS CUI [1,3])
Measurable lesion Quantity
Item
patients have at least one measurable lesion according to recist1.1
boolean
C1513041 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
Karnofsky Performance Status
Item
kps≥80
boolean
C0206065 (UMLS CUI [1])
Prior Therapy Absent Breast Carcinoma
Item
no prior treatment for breast cancer
boolean
C1514463 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0678222 (UMLS CUI [1,3])
Bone Marrow function | Neutrophil count | Platelet Count measurement | Renal function | Creatinine measurement, serum | Creatinine clearance measurement | Liver function | Serum total bilirubin measurement | Alanine aminotransferase measurement | Aspartate aminotransferase measurement | Alkaline phosphatase measurement | Cardiac function ECG | Cardiac function Thoracic Radiography
Item
adequate bone marrow (neutrophil count ≥1500 ml and platelet count ≥100,000 ml), renal (serum creatinine <1.5 times the upper limit of normal [uln] or a creatinine clearance of ≥60 ml/minute), hepatic (total bilirubin ≤1.5 uln; alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase ≤2.5 uln), and cardiac function (assessed by electrocardiogram or thoracic radiography) were required.
boolean
C0005953 (UMLS CUI [1,1])
C0031843 (UMLS CUI [1,2])
C0200633 (UMLS CUI [2])
C0032181 (UMLS CUI [3])
C0232804 (UMLS CUI [4])
C0201976 (UMLS CUI [5])
C0373595 (UMLS CUI [6])
C0232741 (UMLS CUI [7])
C1278039 (UMLS CUI [8])
C0201836 (UMLS CUI [9])
C0201899 (UMLS CUI [10])
C0201850 (UMLS CUI [11])
C0232164 (UMLS CUI [12,1])
C0013798 (UMLS CUI [12,2])
C0232164 (UMLS CUI [13,1])
C3665494 (UMLS CUI [13,2])
Pregnancy | Breast Feeding | Childbearing Potential Contraceptive methods Absent
Item
fertile women were excluded if pregnant or lactating or if they were not using adequate contraception.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C3831118 (UMLS CUI [3,1])
C0700589 (UMLS CUI [3,2])
C0332197 (UMLS CUI [3,3])
Prior Chemotherapy Breast Carcinoma
Item
previous chemotherapy for breast cancer.
boolean
C1514457 (UMLS CUI [1,1])
C0678222 (UMLS CUI [1,2])
Illness Serious | Congestive heart failure | Angina Pectoris | Uncontrolled hypertension | Cardiac Arrhythmia Uncontrolled | Nervous system disorder | Mental disorders | Communicable Disease Serious Uncontrolled | AIDS | Organ Allograft | Gastrointestinal Disease Severe | Cancer Other | Exception Carcinoma in situ of uterine cervix | Exception Skin carcinoma | Exception Malignant Neoplasm Disease Free
Item
history of other serious illness (e.g. congestive heart failure, angina pectoris, uncontrolled hypertension or arrhythmia, clinically significant neurologic or psychiatric disorders, uncontrolled serious infection, aids), had an organ allograft, severe gastrointestinal disorder, or other neoplasias (except for in situ cervical cancer, non-melanoma skin cancer, or previous diagnosis of cancer with no evidence of disease for >10 years).
boolean
C0221423 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C0018802 (UMLS CUI [2])
C0002962 (UMLS CUI [3])
C1868885 (UMLS CUI [4])
C0003811 (UMLS CUI [5,1])
C0205318 (UMLS CUI [5,2])
C0027765 (UMLS CUI [6])
C0004936 (UMLS CUI [7])
C0009450 (UMLS CUI [8,1])
C0205404 (UMLS CUI [8,2])
C0205318 (UMLS CUI [8,3])
C0001175 (UMLS CUI [9])
C0178784 (UMLS CUI [10,1])
C0040739 (UMLS CUI [10,2])
C0017178 (UMLS CUI [11,1])
C0205082 (UMLS CUI [11,2])
C1707251 (UMLS CUI [12])
C1705847 (UMLS CUI [13,1])
C0851140 (UMLS CUI [13,2])
C1705847 (UMLS CUI [14,1])
C0699893 (UMLS CUI [14,2])
C1705847 (UMLS CUI [15,1])
C0006826 (UMLS CUI [15,2])
C0012634 (UMLS CUI [15,3])
C0332296 (UMLS CUI [15,4])