histologically confirmed nsclc (up to and including stage ii) for patients undergoing vats lobectomy. for patients undergoing wedge resection for undiagnosed pulmonary nodule or metastasis from crc, a malignant diagnosis may be confirmed post-operatively.

scheduled for lung resection surgery (lobectomy or wedge resection) involving only one lobe of the lung

willing to give consent and comply with evaluation and treatment schedule

at least 18 years of age

active bacterial infection or fungal infection

systemic administration (intravenous or oral) of steroids (within 30 days prior to study procedure)

chemotherapy or radiation therapy for lung cancer may not be performed for 30 days prior to the procedure

scheduled concurrent surgical procedure other than wedge resection or lobectomy (central venous access - e.g. port placement, mediastinoscopy with lymph node sampling, and vats lymphadenectomy are allowed);

prior history of vats or open lung surgery