consenting patients above 21 years who are mildly symptomatic (those in class ii nyha), who have an intermediate likelihood of cad, or asymptomatic patients who are determined to be at intermediate or high risk of coronary events by the framingham (atp iii) criteria

patients with prior documented cad (by angiography), mi, coronary stenting or bypass surgery

patients in class iii or iv nyha

patients with chronic renal impairment to the extent of precluding contrast injection

severe medical disease with limited expectancy of life

contra-indication or allergy to pharmacologic stress agents or contrast agents

patients with unstable cardiac rhythms (including persistent atrial fibrillation) which preclude good ecg gating

weight limitations due to scanner design

pregnant/ lactating women