Diabetes Mellitus, Non-Insulin-Dependent | Oral medication Quantity
Item
type 2 diabetes treated with one or more oral agents
boolean
C0011860 (UMLS CUI [1])
C0175795 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
Fasting blood glucose level Persistent | Hemoglobin A1c measurement
Item
persistent fasting glucose > 140 mg/dl or hba1c > 7%
boolean
C1261430 (UMLS CUI [1,1])
C0205322 (UMLS CUI [1,2])
C0474680 (UMLS CUI [2])
Oral medication Quantity Stable | Oral medication Effective Maximal
Item
stable and maximally effective doses of one or more oral agents for 3 months
boolean
C0175795 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
C0175795 (UMLS CUI [2,1])
C1280519 (UMLS CUI [2,2])
C0205289 (UMLS CUI [2,3])
Diabetic peripheral neuropathy
Item
presence of diabetic peripheral neuropathy
boolean
C0740447 (UMLS CUI [1])
Age
Item
age between 18 and 70 years
boolean
C0001779 (UMLS CUI [1])
Risk factors Absent Neuropathy | Causes Absent Neuropathy
Item
no risk factors or other causes of neuropathy
boolean
C0035648 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0442874 (UMLS CUI [1,3])
C0015127 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0442874 (UMLS CUI [2,3])
Informed Consent | Compliance behavior Medical procedures
Item
willingness and capacity to sign the institutional review board approved consent form and cooperate with the medical procedures for study duration
boolean
C0021430 (UMLS CUI [1])
C1321605 (UMLS CUI [2,1])
C0199171 (UMLS CUI [2,2])
Breast Feeding | Pregnancy
Item
nursing mothers or pregnant women
boolean
C0006147 (UMLS CUI [1])
C0032961 (UMLS CUI [2])
Kidney Transplantation | Pancreas Transplantation | Heart Transplantation
Item
a history of previous kidney, pancreas or cardiac transplantation
boolean
C0022671 (UMLS CUI [1])
C0030275 (UMLS CUI [2])
C0018823 (UMLS CUI [3])
Neuropathy Independent of Diabetes Mellitus | Disease Associated with Neuropathy | Hepatitis C | Kidney Failure, Chronic | Lupus Erythematosus
Item
a past history of neuropathy (independent of diabetes) or with a disease known to be associated with neuropathy (e.g., hepatitis c, end stage renal disease, lupus)
boolean
C0442874 (UMLS CUI [1,1])
C0332291 (UMLS CUI [1,2])
C0011849 (UMLS CUI [1,3])
C0012634 (UMLS CUI [2,1])
C0332281 (UMLS CUI [2,2])
C0442874 (UMLS CUI [2,3])
C0019196 (UMLS CUI [3])
C0022661 (UMLS CUI [4])
C0409974 (UMLS CUI [5])
Amputation of lower limb Part Any | Traumatic acquired absence Lower extremity part Any | Congenital absence Lower Extremity | Deformity of lower limb Severe
Item
amputation of any part of either lower extremity for any reason or traumatic loss of any part of either lower extremity or congenital absence or severe deformity of lower extremity
boolean
C0337308 (UMLS CUI [1,1])
C0449719 (UMLS CUI [1,2])
C1552551 (UMLS CUI [1,3])
C0259766 (UMLS CUI [2,1])
C1268197 (UMLS CUI [2,2])
C1552551 (UMLS CUI [2,3])
C0332907 (UMLS CUI [3,1])
C0023216 (UMLS CUI [3,2])
C1096086 (UMLS CUI [4,1])
C0205082 (UMLS CUI [4,2])
Hemoglobin A1c measurement
Item
hba1c > 10%
boolean
C0474680 (UMLS CUI [1])
Study Subject Participation Status | Investigational New Drugs
Item
participation in an experimental medication trial within 3 months of starting the study.
boolean
C2348568 (UMLS CUI [1])
C0013230 (UMLS CUI [2])
Therapeutic procedure Malignant disease | Exception Basal cell carcinoma | Exception Squamous cell carcinoma
Item
undergoing therapy for malignant disease other than basal- or squamous cell carcinoma
boolean
C0087111 (UMLS CUI [1,1])
C0442867 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0007137 (UMLS CUI [3,2])
Requirement Glucocorticoid therapy Long-term
Item
requiring long-term glucocorticoid therapy
boolean
C1514873 (UMLS CUI [1,1])
C0744425 (UMLS CUI [1,2])
C0443252 (UMLS CUI [1,3])
Protocol Compliance Unable | Protocol Compliance Unwilling
Item
inability or unwillingness to comply with the protocol
boolean
C0525058 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
C0525058 (UMLS CUI [2,1])
C0558080 (UMLS CUI [2,2])