Adult onset Rheumatoid Arthritis Duration
Item
subjects must have a diagnosis of adult-onset ra of at least 6 months but not longer than 15 years in duration as defined by the 1987 american college of rheumatology classification criteria.
boolean
C1853562 (UMLS CUI [1,1])
C0003873 (UMLS CUI [1,2])
C0449238 (UMLS CUI [1,3])
Rheumatoid Arthritis
Item
subjects must have active ra disease as defined by:
boolean
C0003873 (UMLS CUI [1])
Tender joint count | Swollen joint count
Item
at least 9 tender joints and 9 swollen joints
boolean
C0451530 (UMLS CUI [1])
C0451521 (UMLS CUI [2])
Erythrocyte sedimentation rate measurement | C-reactive protein measurement
Item
esr of 30 mm/hour or crp of 1.5 mg/dl
boolean
C1176468 (UMLS CUI [1])
C0201657 (UMLS CUI [2])
Methotrexate Dose Stable U/week
Item
subjects must have received treatment with mtx for at least 6 months prior to the start of study drug administration. the dose of mtx must have remain fixed for at least 2 months prior to the study and the dose of mtx should be within 6 to 8 mg/week.
boolean
C0025677 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
C0560588 (UMLS CUI [1,4])
Arthritis Other
Item
patients who have a diagnosis of any other inflammatory arthritis
boolean
C0003864 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Arthritis Secondary Noninflammatory | Osteoarthritis | Fibromyalgia
Item
patients who have a secondary, non-inflammatory type of arthritis (eg, osteoarthritis, fibromyalgia)
boolean
C0003864 (UMLS CUI [1,1])
C0175668 (UMLS CUI [1,2])
C0442743 (UMLS CUI [1,3])
C0029408 (UMLS CUI [2])
C0016053 (UMLS CUI [3])
Demyelinating disease of central nervous system | Convulsive disorder Central Nervous System | Multiple Sclerosis | Epilepsy
Item
patients who currently have, or who have a history of, a demyelinating or convulsive disease of the central nervous system (eg, multiple sclerosis, epilepsy)
boolean
C0011302 (UMLS CUI [1])
C0234972 (UMLS CUI [2,1])
C3714787 (UMLS CUI [2,2])
C0026769 (UMLS CUI [3])
C0014544 (UMLS CUI [4])
Congestive heart failure New York Heart Association Classification
Item
patients who have nyha (new york heart association) class iii or iv congestive heart failure
boolean
C0018802 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
Tuberculosis
Item
patients who currently have, or who have a history of, tuberculosis
boolean
C0041296 (UMLS CUI [1])
High risk of Communicable Disease | Communicable Disease | Chronic infectious disease | Communicable Disease Serious
Item
patients who have a high risk of infection (with a current infectious disease, a chronic infectious disease, a history of serious infectious disease)
boolean
C0332167 (UMLS CUI [1,1])
C0009450 (UMLS CUI [1,2])
C0009450 (UMLS CUI [2])
C0151317 (UMLS CUI [3])
C0009450 (UMLS CUI [4,1])
C0205404 (UMLS CUI [4,2])
Malignant Neoplasms
Item
patients who currently have, or who have a history of, malignancy
boolean
C0006826 (UMLS CUI [1])
Breast Feeding | Pregnancy | Childbearing Potential
Item
female patients who are breastfeeding or pregnant, who are of childbearing potential
boolean
C0006147 (UMLS CUI [1])
C0032961 (UMLS CUI [2])
C3831118 (UMLS CUI [3])
Anti-TNF alpha drug Quantity | Anti-TNF alpha drug Quantity Unresponsive to Treatment
Item
patients who previously received treatment with 2 or more anti-tnfα drugs or who previously failed to respond to treatment with 1 or more aint-tnfα drugs.
boolean
C1562242 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C1562242 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
C0205269 (UMLS CUI [2,3])