Age
Item
male and female subjects above 50 years of age
boolean
C0001779 (UMLS CUI [1])
Arthralgia Due to Rheumatoid Arthritis
Item
suffering from joint pain which is due to active rheumatoid arthritis
boolean
C0003862 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C0003873 (UMLS CUI [1,3])
Signs Inflammation Joints Quantity | Swelling | Erythema | Temperature elevated Local
Item
obvious signs of inflammation in at least one joint (e.g. swelling, erythema, or local elevated temperature)
boolean
C0311392 (UMLS CUI [1,1])
C0021368 (UMLS CUI [1,2])
C0022417 (UMLS CUI [1,3])
C1265611 (UMLS CUI [1,4])
C0038999 (UMLS CUI [2])
C0041834 (UMLS CUI [3])
C0437737 (UMLS CUI [4,1])
C0205276 (UMLS CUI [4,2])
General status Healthy
Item
otherwise healthy
boolean
C0947124 (UMLS CUI [1,1])
C3898900 (UMLS CUI [1,2])
Informed Consent
Item
informed consent
boolean
C0021430 (UMLS CUI [1])
Age
Item
patients 80 years and older
boolean
C0001779 (UMLS CUI [1])
Cardiovascular Disease | Respiration Disorder | Hepatobiliary disease | CNS disorder
Item
clinically significant disease of the cardiovascular system, respiratory system, hepato-biliary system or central nervous system (cns)
boolean
C0007222 (UMLS CUI [1])
C0035204 (UMLS CUI [2])
C0267792 (UMLS CUI [3])
C0007682 (UMLS CUI [4])
Hepatic Insufficiency Excretory | Renal Insufficiency Excretory
Item
excretory hepatic or renal insufficiency
boolean
C1306571 (UMLS CUI [1,1])
C0221102 (UMLS CUI [1,2])
C1565489 (UMLS CUI [2,1])
C0221102 (UMLS CUI [2,2])
Drug use Regular | Exception Hormone replacement therapy Gender
Item
regular intake of any drug, except for hormone replacement therapy in females
boolean
C0242510 (UMLS CUI [1,1])
C0205272 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0282402 (UMLS CUI [2,2])
C0079399 (UMLS CUI [2,3])
Proteins Heterogenous
Item
previous administration of xenogenous proteins
boolean
C0033684 (UMLS CUI [1,1])
C1512426 (UMLS CUI [1,2])
Anaphylaxis Drug Parenteral Administration
Item
history of anaphylactic reaction to any drug administered by a parenteral pathway
boolean
C0002792 (UMLS CUI [1,1])
C0013227 (UMLS CUI [1,2])
C1518896 (UMLS CUI [1,3])
Study Subject Participation Status | Radiopharmaceuticals
Item
previous participation in a radiopharmaceutical drug trial (unless the effective dose acquired by participation in the current trial will remain below 10 msv)
boolean
C2348568 (UMLS CUI [1])
C0182638 (UMLS CUI [2])
Study Subject Participation Status | Investigational New Drugs
Item
participation in any clinical drug trial within 3 months prior to enrolment
boolean
C2348568 (UMLS CUI [1])
C0013230 (UMLS CUI [2])
Childbearing Potential | Factor out ruling Childbearing Potential | Postmenopausal state | Hysterectomy | Bilateral oophorectomy | Bilateral tubal ligation
Item
women of child-bearing potential (child-bearing potential to be ruled out by one of the following: at least 2 years past menopause, hysterectomy, bilateral oophorectomy, or bilateral tubal ligation)
boolean
C3831118 (UMLS CUI [1])
C1521761 (UMLS CUI [2,1])
C0332196 (UMLS CUI [2,2])
C3831118 (UMLS CUI [2,3])
C0232970 (UMLS CUI [3])
C0020699 (UMLS CUI [4])
C0278321 (UMLS CUI [5])
C0589114 (UMLS CUI [6])
Pharmaceutical Preparations Long-term | Antiphlogistic agent Strong | Analgesics Strong | Methotrexate | Adrenal Cortex Hormones | Immunosuppressive Agents
Item
long term medication with strong antiphlogistic agents/pain killers such as methotrexate, corticoids, or immunosuppressants prior to enrolment
boolean
C0013227 (UMLS CUI [1,1])
C0443252 (UMLS CUI [1,2])
C0304344 (UMLS CUI [2,1])
C0442821 (UMLS CUI [2,2])
C0002771 (UMLS CUI [3,1])
C0442821 (UMLS CUI [3,2])
C0025677 (UMLS CUI [4])
C0001617 (UMLS CUI [5])
C0021081 (UMLS CUI [6])