Adenocarcinoma of the prostate metastatic | Adenocarcinoma of prostate unresectable
Item
histologically or cytologically confirmed adenocarcinoma of the prostate which is metastatic and/or unresectable
boolean
C0862636 (UMLS CUI [1])
C0007112 (UMLS CUI [2,1])
C1519810 (UMLS CUI [2,2])
Hormone refractory prostate cancer Progressive | Raised prostate specific antigen Quantity
Item
hormone refractory prostate cancer defined as progressive based by documented 2 increase psa values over a previous reference value.
boolean
C1328504 (UMLS CUI [1,1])
C0205329 (UMLS CUI [1,2])
C0178415 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
ECOG performance status
Item
ecog status 0-2
boolean
C1520224 (UMLS CUI [1])
Hematologic function | Liver function | Renal function
Item
adequate hematological functions, liver and renal functions
boolean
C0221130 (UMLS CUI [1])
C0232741 (UMLS CUI [2])
C0232804 (UMLS CUI [3])
Hypersensitivity Docetaxel | Hypersensitivity Taxane
Item
known hypersensitivity to docetaxel or taxane therapy
boolean
C0020517 (UMLS CUI [1,1])
C0246415 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0215136 (UMLS CUI [2,2])
CNS metastases | Metastatic Malignant Neoplasm to the Leptomeninges
Item
documented central nervous system or leptomeningeal metastasis at time of study entry
boolean
C0686377 (UMLS CUI [1])
C1704231 (UMLS CUI [2])
Prior Chemotherapy | Bone-seeking Radioisotope | Therapeutic radiology procedure Bone Marrow Percentage
Item
had prior treatment with chemotherapy, bone seeking radionucleides in past 6 weeks prior to enrollment, or radiotherapy involving more than 25% of marrow producing area.
boolean
C1514457 (UMLS CUI [1])
C2985504 (UMLS CUI [2])
C1522449 (UMLS CUI [3,1])
C0005953 (UMLS CUI [3,2])
C0439165 (UMLS CUI [3,3])
Secondary malignant neoplasm of bone Painful | Secondary malignant neoplasm of bone Destruction | Therapeutic radiology procedure Required | Diphosphonates Required | Bone-seeking Radioisotope Required
Item
evidence of painful and/or destructive bone metastases for which radiation therapy, biophosphonates or boneseeking radionucleides are necessary.
boolean
C0153690 (UMLS CUI [1,1])
C0030193 (UMLS CUI [1,2])
C0153690 (UMLS CUI [2,1])
C1948029 (UMLS CUI [2,2])
C1522449 (UMLS CUI [3,1])
C1514873 (UMLS CUI [3,2])
C0012544 (UMLS CUI [4,1])
C1514873 (UMLS CUI [4,2])
C2985504 (UMLS CUI [5,1])
C1514873 (UMLS CUI [5,2])
Drugs, Non-Prescription
Item
have received treatment in the last 30 day with a drug which has not received regulatory approval for any indication at the time of study entry.
boolean
C0013231 (UMLS CUI [1])