Age
Item
the subject is 60 years old or older.
boolean
C0001779 (UMLS CUI [1])
Mild cognitive disorder; criteria; Fulfill
Item
the subject meets the petersen criteria for amnestic mci.
boolean
C1270972 (UMLS CUI [1,1])
C0243161 (UMLS CUI [1,2])
C1550543 (UMLS CUI [1,3])
Modified Hachinski Ischemic Scale-NACC Version Questionnaire
Item
the subject has a score of less than or equal to 4 on the modified hachinski ischemic scale.
boolean
C3826978 (UMLS CUI [1])
mini-mental status exam score (___/30)
Item
the subject has a mmse score of 24-30.
boolean
C2225229 (UMLS CUI [1])
MRI without contrast; visit for screening exam | Mild cognitive disorder; Amnestic Disorder; Structural brain disorders; Exclude
Item
the subject has a non-contrast mri examination as part of the screening visit that excludes amci arising from structural causes.
boolean
C0202670 (UMLS CUI [1,1])
C2097637 (UMLS CUI [1,2])
C1270972 (UMLS CUI [2,1])
C0002625 (UMLS CUI [2,2])
C0851391 (UMLS CUI [2,3])
C0332196 (UMLS CUI [2,4])
Informed Consent
Item
the subject and/or the subject's legally acceptable representative, if applicable, in accordance with local regulations, has signed and dated an informed consent.
boolean
C0021430 (UMLS CUI [1])
nervous system disorder; Significant | Mild cognitive disorder; Amnestic Disorder; Other | Parkinson Disease | Huntington Disease | Hydrocephalus, Normal Pressure | Brain Neoplasms | Supranuclear paralysis | Epilepsy | Hematoma, Subdural | Multiple Sclerosis | Craniocerebral Trauma; Neurologic Deficits; Persistent | Structural brain abnormalities
Item
the subject has any significant neurologic disease other than suspected amci; such as parkinson's disease, huntington's disease, normal pressure hydrocephalus, brain tumor, supranuclear palsy, seizure disorder, subdural hematoma, multiple sclerosis, or history of significant head trauma followed by persistent neurologic deficits, or known structural brain abnormalities.
boolean
C0027765 (UMLS CUI [1,1])
C0750502 (UMLS CUI [1,2])
C1270972 (UMLS CUI [2,1])
C0002625 (UMLS CUI [2,2])
C0205394 (UMLS CUI [2,3])
C0030567 (UMLS CUI [3])
C0020179 (UMLS CUI [4])
C0020258 (UMLS CUI [5])
C0006118 (UMLS CUI [6])
C0270920 (UMLS CUI [7])
C0014544 (UMLS CUI [8])
C0018946 (UMLS CUI [9])
C0026769 (UMLS CUI [10])
C0018674 (UMLS CUI [11,1])
C0521654 (UMLS CUI [11,2])
C0205322 (UMLS CUI [11,3])
C1866933 (UMLS CUI [12])
Aneurysm clip | Heart Valve Prosthesis | Implants; Metals | Fragment of (qualifier value); Metals | Pacemakers | Magnetic Resonance Imaging; risk factors
Item
the subject has one or more aneurysm clips, artificial heart valves, metal implants, embedded metal fragments or pacemakers that would pose a risk during an mri.
boolean
C0179977 (UMLS CUI [1])
C0018825 (UMLS CUI [2])
C0021102 (UMLS CUI [3,1])
C0025552 (UMLS CUI [3,2])
C0332255 (UMLS CUI [4,1])
C0025552 (UMLS CUI [4,2])
C0810633 (UMLS CUI [5])
C0024485 (UMLS CUI [6,1])
C0035648 (UMLS CUI [6,2])
Major Depressive Disorder | Bipolar Disorder | DSM-IV; Past Year
Item
the subject has major depression, bipolar disorder, as described in the dsm-iv within the past year.
boolean
C1269683 (UMLS CUI [1])
C0005586 (UMLS CUI [2])
C0220952 (UMLS CUI [3,1])
C4086728 (UMLS CUI [3,2])
Schizophrenia | DSM-IV
Item
the subject has history of schizophrenia (dsm-iv criteria).
boolean
C0036341 (UMLS CUI [1])
C0220952 (UMLS CUI [2])
Psychotic symptom; Time | Agitation; Time | Behavior Disorders; Time | Protocol Compliance
Item
the subject has had, within the prior 3 months, psychotic features, agitation or behavioral problems that could lead to protocol compliance issues.
boolean
C0871189 (UMLS CUI [1,1])
C0040223 (UMLS CUI [1,2])
C0085631 (UMLS CUI [2,1])
C0040223 (UMLS CUI [2,2])
C0004930 (UMLS CUI [3,1])
C0040223 (UMLS CUI [3,2])
C0525058 (UMLS CUI [4])