Age | ECOG performance status
Item
patients who were≥ 65 years of age and they had an easten cooperative oncology group (ecog) performance status (ps) of 0-2, or the patients who were < 65 years of age and they had an ecog ps 2
boolean
C0001779 (UMLS CUI [1])
C1520224 (UMLS CUI [2])
Non-small cell carcinoma
Item
histologically confirmed non-small cell carcinoma
boolean
C1266002 (UMLS CUI [1])
Disease TNM clinical staging
Item
stages iiib-iv disease
boolean
C0012634 (UMLS CUI [1,1])
C3258246 (UMLS CUI [1,2])
Parameters Hematologic | Hemoglobin measurement | Absolute neutrophil count | Platelet Count measurement | Renal function | Creatinine measurement, serum | Liver function | Serum total bilirubin measurement | Transaminase Assay
Item
adequate hematologic parameters (hemoglobin concentration of at least 9.0 g/dl, absolute neutrophil count ≥1,500/mm3, and platelet count ≥100,000/mm3), renal function (serum creatinine ≤1.5 mg/dl), and liver function (total bilirubin ≤1.5 mg/dl and serum transaminase level less than twice the upper limit of normal)
boolean
C0449381 (UMLS CUI [1,1])
C0205488 (UMLS CUI [1,2])
C0518015 (UMLS CUI [2])
C0948762 (UMLS CUI [3])
C0032181 (UMLS CUI [4])
C0232804 (UMLS CUI [5])
C0201976 (UMLS CUI [6])
C0232741 (UMLS CUI [7])
C1278039 (UMLS CUI [8])
C0919834 (UMLS CUI [9])
Measurable lesion 2-Dimensional Quantity
Item
at least one bi-dimensionally measurable lesion, according to the response evaluation criteria in solid tumors (recist) version 1.1
boolean
C1513041 (UMLS CUI [1,1])
C1705052 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
Communicable Disease
Item
active infection
boolean
C0009450 (UMLS CUI [1])
Prior Chemotherapy Disease | Prior radiation therapy Disease | Operative Surgical Procedures Previous Disease
Item
prior chemotherapy, radiotherapy or surgery for their disease,
boolean
C1514457 (UMLS CUI [1,1])
C0012634 (UMLS CUI [1,2])
C0279134 (UMLS CUI [2,1])
C0012634 (UMLS CUI [2,2])
C0543467 (UMLS CUI [3,1])
C0205156 (UMLS CUI [3,2])
C0012634 (UMLS CUI [3,3])
Myocardial Infarction
Item
a history of myocardial infarction in the last 3 months before entry to the study
boolean
C0027051 (UMLS CUI [1])
Congestive heart failure Uncontrolled | Uncontrolled hypertension
Item
uncontrolled congestive heart failure or hypertension
boolean
C0018802 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C1868885 (UMLS CUI [2])
Diabetic - poor control | Pregnancy | Breast Feeding | Second Primary Cancers | Exception Carcinoma in situ of uterine cervix | Exception Skin carcinoma
Item
uncontrolled diabetes mellitus, pregnancy, lactation or a prior second primary cancer except for cervix cancer in situ or skin cancer
boolean
C0421258 (UMLS CUI [1])
C0032961 (UMLS CUI [2])
C0006147 (UMLS CUI [3])
C0751623 (UMLS CUI [4])
C1705847 (UMLS CUI [5,1])
C0851140 (UMLS CUI [5,2])
C1705847 (UMLS CUI [6,1])
C0699893 (UMLS CUI [6,2])
Informed Consent
Item
all the patients provided written informed consent before they entered the study
boolean
C0021430 (UMLS CUI [1])