Age
Item
age ≥18 years
boolean
C0001779 (UMLS CUI [1])
Non-Small Cell Lung Carcinoma Advanced Locally TNM clinical staging | Pleural effusion Absent
Item
patients with histologically or cytologically documented diagnosis of locally advanced nsclc stage iib to iiib without pleural effusion
boolean
C0007131 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C1517927 (UMLS CUI [1,3])
C3258246 (UMLS CUI [1,4])
C0032227 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
ECOG performance status
Item
performance status 0-1 on the ecog scale
boolean
C1520224 (UMLS CUI [1])
Weight decreased Percentage Timespan
Item
weight loss ≤10% during the last 6 months
boolean
C1262477 (UMLS CUI [1,1])
C0439165 (UMLS CUI [1,2])
C0872291 (UMLS CUI [1,3])
Pulmonary function FEV1
Item
adequate lung function measured as fev1 ≥1.0
boolean
C0231921 (UMLS CUI [1,1])
C0849974 (UMLS CUI [1,2])
Neutrophil count | Platelet Count measurement
Item
neutrophile count ≥1.5 x 109/l and platelet count ≥100 x 109/l
boolean
C0200633 (UMLS CUI [1])
C0032181 (UMLS CUI [2])
Serum total bilirubin measurement
Item
serum bilirubin ≤1.5 upper limit of normal (uln)
boolean
C1278039 (UMLS CUI [1])
Alanine aminotransferase measurement
Item
alat ≤2 x uln
boolean
C0201836 (UMLS CUI [1])
Protocol Compliance
Item
able to comply with study and follow-up procedures
boolean
C0525058 (UMLS CUI [1])
Females & males of reproductive potential Contraceptive methods
Item
patients with reproductive potential must use effective contraception
boolean
C4034483 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Informed Consent
Item
written (signed) informed consent to participate in the study
boolean
C0021430 (UMLS CUI [1])
Systemic disease Unstable | Communicable Disease | Angina, Unstable | Congestive heart failure | Liver disease Severe | Kidney Disease Severe | Metabolic Disease Severe
Item
any unstable systemic disease (including active infection, unstable angina, congestive heart failure, severe hepatic, renal, or metabolic disease)
boolean
C0442893 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])
C0009450 (UMLS CUI [2])
C0002965 (UMLS CUI [3])
C0018802 (UMLS CUI [4])
C0023895 (UMLS CUI [5,1])
C0205082 (UMLS CUI [5,2])
C0022658 (UMLS CUI [6,1])
C0205082 (UMLS CUI [6,2])
C0025517 (UMLS CUI [7,1])
C0205082 (UMLS CUI [7,2])
Cancer Other | Exception Carcinoma in situ of uterine cervix Treated | Exception Basal cell carcinoma Treated | Exception Squamous cell carcinoma of skin Treated
Item
any other active malignancies within 5 years (except for adequately treated carcinoma in situ of the cervix or basal or squamous cell skin cancer)
boolean
C1707251 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0851140 (UMLS CUI [2,2])
C1522326 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C0007117 (UMLS CUI [3,2])
C1522326 (UMLS CUI [3,3])
C1705847 (UMLS CUI [4,1])
C0553723 (UMLS CUI [4,2])
C1522326 (UMLS CUI [4,3])
Prior Chemotherapy Malignant neoplasm of lung | Chemotherapy Neoadjuvant Malignant neoplasm of lung | Adjuvant Chemotherapy Malignant neoplasm of lung
Item
prior chemotherapy for lung cancer, including neo- and adjuvant chemotherapy
boolean
C1514457 (UMLS CUI [1,1])
C0242379 (UMLS CUI [1,2])
C0392920 (UMLS CUI [2,1])
C0600558 (UMLS CUI [2,2])
C0242379 (UMLS CUI [2,3])
C0085533 (UMLS CUI [3,1])
C0242379 (UMLS CUI [3,2])
Lacking Able to swallow Oral medication | Requirement Intravenous Feeding
Item
inability to take oral medication, or requirement of intravenous alimentation
boolean
C0332268 (UMLS CUI [1,1])
C2712086 (UMLS CUI [1,2])
C0175795 (UMLS CUI [1,3])
C1514873 (UMLS CUI [2,1])
C0021910 (UMLS CUI [2,2])
Peptic Ulcer
Item
active peptic ulcer disease
boolean
C0030920 (UMLS CUI [1])
Breast Feeding
Item
nursing mothers
boolean
C0006147 (UMLS CUI [1])