Non-Small Cell Lung Carcinoma TNM clinical staging | Non-small cell lung cancer recurrent
Item
histologically documented non-small cell lung cancer, stages 3b, 4 or recurrent
boolean
C0007131 (UMLS CUI [1,1])
C3258246 (UMLS CUI [1,2])
C0278517 (UMLS CUI [2])
Pleural Effusion, Malignant
Item
pleural effusion cytologically proven to be malignant
boolean
C0080032 (UMLS CUI [1])
Prior Chemotherapy Quantity Non-Small Cell Lung Carcinoma | Adjuvant Chemotherapy Post Excision | Chemoradiotherapy
Item
0 or 1 prior chemotherapy regimens for non-small cell lung cancer (adjuvant chemotherapy post resection, or concurrent chemo-radiation therapy counts as one regimen regardless of number of agents used.)
boolean
C1514457 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0007131 (UMLS CUI [1,3])
C0085533 (UMLS CUI [2,1])
C0687676 (UMLS CUI [2,2])
C0728940 (UMLS CUI [2,3])
C0436307 (UMLS CUI [3])
Chemotherapy Planned Non-Small Cell Lung Carcinoma | Cisplatin | Carboplatin | docetaxel | Paclitaxel | pemetrexed | gemcitabine | vinorelbine | Angiogenesis Inhibitors | bevacizumab | Tyrosine Kinase Inhibitors Excluded | Growth Factor Receptor Inhibitors Excluded
Item
planning to start chemotherapy for non-small cell lung cancer (treatment regimen at discretion of treating physician but must include one or more of the following agents:cisplatin,carboplatin,docetaxel,paclitaxel, pemetrexed,gemcitabine,vinorelbine) patients may receive anti-angiogenesis agents (bevacizumab) in addition to chemotherapy, but patients treated solely with tyrosine kinase inhibitors or growth-factor receptor blockers are not eligible.
boolean
C0392920 (UMLS CUI [1,1])
C1301732 (UMLS CUI [1,2])
C0007131 (UMLS CUI [1,3])
C0008838 (UMLS CUI [2])
C0079083 (UMLS CUI [3])
C0246415 (UMLS CUI [4])
C0144576 (UMLS CUI [5])
C0210657 (UMLS CUI [6])
C0045093 (UMLS CUI [7])
C0078257 (UMLS CUI [8])
C0596087 (UMLS CUI [9])
C0796392 (UMLS CUI [10])
C2757011 (UMLS CUI [11,1])
C0332196 (UMLS CUI [11,2])
C0206454 (UMLS CUI [12,1])
C0243077 (UMLS CUI [12,2])
C0332196 (UMLS CUI [12,3])
Prior radiation therapy
Item
prior radiation therapy is permitted.
boolean
C0279134 (UMLS CUI [1])
Performance status
Item
performance status 0,1,2
boolean
C1518965 (UMLS CUI [1])
Creatinine measurement, serum | Estimation of creatinine clearance by Cockcroft-Gault formula
Item
serum creatinine less than 2.0 or estimated creatinine clearance over 30cc/min by calcroft/gault equation
boolean
C0201976 (UMLS CUI [1])
C2711451 (UMLS CUI [2])
Life Expectancy
Item
estimated life expectancy over 3 months
boolean
C0023671 (UMLS CUI [1])
Informed Consent
Item
signed informed consent
boolean
C0021430 (UMLS CUI [1])
Age
Item
age greater than 18 years
boolean
C0001779 (UMLS CUI [1])
Indication Zometa | Secondary malignant neoplasm of bone Osteolytic | Hypercalcemia
Item
patients who have clinical indication for zometa treatment such as lytic bone metastases or hypercalcemia can be included
boolean
C3146298 (UMLS CUI [1,1])
C0939788 (UMLS CUI [1,2])
C0153690 (UMLS CUI [2,1])
C0302846 (UMLS CUI [2,2])
C0020437 (UMLS CUI [3])
Pregnancy | Breast Feeding
Item
pregnant or lactating
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Comorbidity Preventing Protocol Compliance | Mental disorders Preventing Protocol Compliance
Item
patient with concurrent medical or psychiatric illness which would, in the opinion of the investigator, prevent compliance with the study
boolean
C0009488 (UMLS CUI [1,1])
C1292733 (UMLS CUI [1,2])
C0525058 (UMLS CUI [1,3])
C0004936 (UMLS CUI [2,1])
C1292733 (UMLS CUI [2,2])
C0525058 (UMLS CUI [2,3])
Procedure Any | Exception Thoracentesis Drainage Effusion | Thoracentesis Quantity | Chest tube placement Excluded | Exclusion Catheter Transthoracic Permanent | Pleurodesis Excluded | Thoracoscopy Excluded
Item
patients who undergo any procedure other than thoracentesis for drainage of effusion.patients may have had more than one thoracentesis prior to study. patients who have large bore chest tube placement, permanent transthoracic catheter (pleurex), medical pleurodesis or thoracoscopy are excluded.
boolean
C0184661 (UMLS CUI [1,1])
C1552551 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0189477 (UMLS CUI [2,2])
C0013103 (UMLS CUI [2,3])
C0013687 (UMLS CUI [2,4])
C0189477 (UMLS CUI [3,1])
C1265611 (UMLS CUI [3,2])
C0742344 (UMLS CUI [4,1])
C0332196 (UMLS CUI [4,2])
C2828389 (UMLS CUI [5,1])
C0085590 (UMLS CUI [5,2])
C4049694 (UMLS CUI [5,3])
C0205355 (UMLS CUI [5,4])
C0189557 (UMLS CUI [6,1])
C0332196 (UMLS CUI [6,2])
C0039989 (UMLS CUI [7,1])
C0332196 (UMLS CUI [7,2])
Tooth problem | Infection of tooth | Maxilla infection | Infection Mandible | Dental trauma | Trauma Fixture dental | Necrosis of bone of jaw | Exposed bone of oral vestibule | Healing Slow Post Dental Procedure
Item
current active dental problems including infection of the teeth or jawbone (maxilla or mandibular);dental or fixture trauma, or a current or prior diagnosis of osteonecrosis of the jaw (onj), of exposed bone in the mouth, or of slow healing after dental procedures.
boolean
C0576962 (UMLS CUI [1])
C0877046 (UMLS CUI [2])
C1400602 (UMLS CUI [3])
C3714514 (UMLS CUI [4,1])
C0024687 (UMLS CUI [4,2])
C1301685 (UMLS CUI [5])
C3714660 (UMLS CUI [6,1])
C3879289 (UMLS CUI [6,2])
C2711248 (UMLS CUI [7])
C2013525 (UMLS CUI [8])
C0043240 (UMLS CUI [9,1])
C0439834 (UMLS CUI [9,2])
C0687676 (UMLS CUI [9,3])
C0011331 (UMLS CUI [9,4])
Dental surgical procedure | Jaw Surgery | Dental surgical procedure Planned | Jaw Surgery Planned | Tooth Extraction | Jaw Extraction | Dental Implant | Jaw implant
Item
recent (within 6 weeks)or planned dental or jaw surgery (e.g.extraction, implants).
boolean
C0204324 (UMLS CUI [1])
C0407713 (UMLS CUI [2])
C0204324 (UMLS CUI [3,1])
C1301732 (UMLS CUI [3,2])
C0407713 (UMLS CUI [4,1])
C1301732 (UMLS CUI [4,2])
C0040440 (UMLS CUI [5])
C0022359 (UMLS CUI [6,1])
C0185115 (UMLS CUI [6,2])
C0011370 (UMLS CUI [7])
C0441366 (UMLS CUI [8])