Outpatients | Age
Item
are outpatients, male or female, 30 through 75 years of age
boolean
C0029921 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Major depressive episode | Parkinson Disease
Item
meet diagnostic criteria for major depression episode and a clinical diagnosis of idiopathic parkinson's disease
boolean
C0024517 (UMLS CUI [1])
C0030567 (UMLS CUI [2])
Hamilton Depression Rating Scale 17 Item Clinical Classification | Beck depression inventory | CGI - Severity of Illness
Item
have a clinician-rated 17-item hamilton depression rating scale (hamd17) total score greater than or equal to 15, a beck depression inventory (bdi) total score greater than or equal to 13 and a clinical global impression of severity (cgi-s) score greater than or equal to 3 at both visit 1 and visit 2
boolean
C3639712 (UMLS CUI [1])
C0451022 (UMLS CUI [2])
C3639887 (UMLS CUI [3])
Cognitive function satisfactory
Item
have satisfactory cognitive function
boolean
C0392335 (UMLS CUI [1,1])
C0205410 (UMLS CUI [1,2])
Antiparkinson Agents Dosage Stable
Item
have been held on stable dosage of antiparkinsonian medications for at least 4 weeks immediately prior to visit 1
boolean
C0003405 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
Psychiatric Diagnosis Except Major depressive episode | Personality Disorder Interferes with Protocol Compliance
Item
any current primary psychiatric diagnosis other than major depressive episode, and any personality disorder that could interfere with the compliance with the study protocol
boolean
C0376338 (UMLS CUI [1,1])
C0332300 (UMLS CUI [1,2])
C0024517 (UMLS CUI [1,3])
C0031212 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C0525058 (UMLS CUI [2,3])
Atypical Parkinsonism | Secondary Parkinson Disease | Etiology Pharmaceutical Preparations Feature Parkinson Disease | Etiology Disease Feature Parkinson Disease
Item
atypical or secondary parkinsonism due to drugs or diseases with features of parkinson's disease
boolean
C4302185 (UMLS CUI [1])
C0030569 (UMLS CUI [2])
C0015127 (UMLS CUI [3,1])
C0013227 (UMLS CUI [3,2])
C2348519 (UMLS CUI [3,3])
C0030567 (UMLS CUI [3,4])
C0015127 (UMLS CUI [4,1])
C0012634 (UMLS CUI [4,2])
C2348519 (UMLS CUI [4,3])
C0030567 (UMLS CUI [4,4])
Motor nerve Condition Changing Antiparkinson Agents
Item
motor conditions for which it is to be expected to change the antiparkinsonian treatment during the course of the study
boolean
C0501384 (UMLS CUI [1,1])
C0348080 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
C0003405 (UMLS CUI [1,4])
Laboratory test result abnormal | Illness Serious Unstable
Item
clinically significant laboratory abnormalities or serious, unstable medical illness
boolean
C0438215 (UMLS CUI [1])
C0221423 (UMLS CUI [2,1])
C0205404 (UMLS CUI [2,2])
C0443343 (UMLS CUI [2,3])
Depressive episode Unresponsive to Treatment | Antidepressive Agents | Course Quantity
Item
lack of response of current episode to two or more adequate courses of antidepressant therapy
boolean
C0349217 (UMLS CUI [1,1])
C0205269 (UMLS CUI [1,2])
C0003289 (UMLS CUI [2])
C0750729 (UMLS CUI [3,1])
C1265611 (UMLS CUI [3,2])