Age
Item
subjects must be male or female between the ages of 18 and 64, inclusive, at the time of signing consent.
boolean
C0001779 (UMLS CUI [1])
Major Depressive Disorder Principal diagnosis
Item
subjects must have a primary diagnosis of major depressive disorder (mdd) by dsm-iv criteria (296.xx) as determined by the mini international neuropsychiatric interview (m.i.n.i.).
boolean
C1269683 (UMLS CUI [1,1])
C0332137 (UMLS CUI [1,2])
Major Depressive Disorder Patient motivation Therapeutic procedure
Item
mdd must be the condition that was chiefly responsible for motivating the subject to seek treatment.
boolean
C1269683 (UMLS CUI [1,1])
C0679856 (UMLS CUI [1,2])
C0087111 (UMLS CUI [1,3])
Hamilton Depression Rating Scale 17 Item Clinical Classification
Item
subjects must have a 17-item hamilton depression scale (ham-d-17) total score of > 22 at the screening visit.
boolean
C3639712 (UMLS CUI [1])
Hamilton Depression Rating Scale 17 Item Clinical Classification
Item
subjects who have a ham-d-17 total score < 18 at visit 2 will be discontinued from the study.
boolean
C3639712 (UMLS CUI [1])
Absence Sleeplessness Relationship Major Depressive Disorder
Item
all subjects who do not meet dsm-iv criteria (307.42) for insomnia related to a major depressive disorder.
boolean
C0332197 (UMLS CUI [1,1])
C0917801 (UMLS CUI [1,2])
C0439849 (UMLS CUI [1,3])
C1269683 (UMLS CUI [1,4])
Time for rest and sleep Hour Quantity | Frequency per week Duration
Item
subjects with less than a total sleep time < 6.5 hours at least three times per week over the past month.
boolean
C1822180 (UMLS CUI [1,1])
C0439227 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C0439603 (UMLS CUI [2,1])
C0332174 (UMLS CUI [2,2])
C0449238 (UMLS CUI [2,3])