Mantle cell lymphoma
Item
histologically confirmed mantle cell lymphoma
boolean
C0334634 (UMLS CUI [1])
Disease untreated
Item
previously untreated disease
boolean
C0012634 (UMLS CUI [1,1])
C0332155 (UMLS CUI [1,2])
Measurable Disease | Evaluable Disease
Item
measurable or evaluable disease
boolean
C1513041 (UMLS CUI [1])
C1516986 (UMLS CUI [2])
Exclusion Central Nervous System Involvement
Item
no cns involvement
boolean
C2828389 (UMLS CUI [1,1])
C4050309 (UMLS CUI [1,2])
Client Characteristics
Item
patient characteristics:
boolean
C0815172 (UMLS CUI [1])
ECOG performance status
Item
ecog performance status 0-2
boolean
C1520224 (UMLS CUI [1])
Life Expectancy
Item
life expectancy > 6 months
boolean
C0023671 (UMLS CUI [1])
Serum total bilirubin measurement
Item
bilirubin < 3 mg/dl
boolean
C1278039 (UMLS CUI [1])
Aspartate aminotransferase measurement | Alanine aminotransferase measurement | Exception Etiology Lymphomatous nodal involvement
Item
sgot and sgpt < 2.5 times upper limit of normal (unless due to lymphomatous involvement)
boolean
C0201899 (UMLS CUI [1])
C0201836 (UMLS CUI [2])
C1705847 (UMLS CUI [3,1])
C0015127 (UMLS CUI [3,2])
C0441949 (UMLS CUI [3,3])
Creatinine measurement, serum
Item
serum creatinine < 1.5 mg/dl
boolean
C0201976 (UMLS CUI [1])
Pregnancy Absent | Breast Feeding Absent
Item
not pregnant or nursing
boolean
C0032961 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0006147 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Pregnancy test negative
Item
negative pregnancy test
boolean
C0427780 (UMLS CUI [1])
Fertility Contraceptive methods
Item
fertile patients must use effective contraception
boolean
C0015895 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Exclusion Heart failure New York Heart Association Classification
Item
no grade 3-4 cardiac failure
boolean
C2828389 (UMLS CUI [1,1])
C0018801 (UMLS CUI [1,2])
C1275491 (UMLS CUI [1,3])
Left ventricular ejection fraction
Item
lvef ≥ 50%
boolean
C0428772 (UMLS CUI [1])
Exclusion Criteria | HIV Infection | Acquired Immunodeficiency Syndrome
Item
no known history of hiv or aids
boolean
C0680251 (UMLS CUI [1])
C0019693 (UMLS CUI [2])
C0001175 (UMLS CUI [3])
Exclusion Criteria | Hepatitis | Hepatitis B
Item
no hepatitis or hepatitis b virus infection
boolean
C0680251 (UMLS CUI [1])
C0019158 (UMLS CUI [2])
C0019163 (UMLS CUI [3])
Exclusion Cancer Other | Exception Carcinoma in situ of uterine cervix | Exception Basal cell carcinoma
Item
no other concurrent active malignancy, except carcinoma in situ of the cervix and basal cell carcinoma of the skin
boolean
C2828389 (UMLS CUI [1,1])
C1707251 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0851140 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0007117 (UMLS CUI [3,2])
Exclusion Criteria | Mental condition Preventing Protocol Compliance | Condition Familial Preventing Protocol Compliance | Sociological Factors Preventing Protocol Compliance | Geographic Factors Preventing Protocol Compliance
Item
no psychological, familial, sociological, or geographical conditions that would prohibit treatment and/or medical follow-up required to comply with study protocol
boolean
C0680251 (UMLS CUI [1])
C3840291 (UMLS CUI [2,1])
C1292733 (UMLS CUI [2,2])
C0525058 (UMLS CUI [2,3])
C0348080 (UMLS CUI [3,1])
C0241888 (UMLS CUI [3,2])
C1292733 (UMLS CUI [3,3])
C0525058 (UMLS CUI [3,4])
C3850138 (UMLS CUI [4,1])
C1292733 (UMLS CUI [4,2])
C0525058 (UMLS CUI [4,3])
C0017444 (UMLS CUI [5,1])
C1292733 (UMLS CUI [5,2])
C0525058 (UMLS CUI [5,3])
Therapeutic procedure
Item
prior concurrent therapy:
boolean
C0087111 (UMLS CUI [1])
Exclusion Criteria | Chemotherapy Lymphoma | Immunotherapy Lymphoma | Therapeutic radiology procedure Lymphoma
Item
no prior chemotherapy, immunotherapy, or radiotherapy for this lymphoma
boolean
C0680251 (UMLS CUI [1])
C0392920 (UMLS CUI [2,1])
C0024299 (UMLS CUI [2,2])
C0021083 (UMLS CUI [3,1])
C0024299 (UMLS CUI [3,2])
C1522449 (UMLS CUI [4,1])
C0024299 (UMLS CUI [4,2])