Chronic Lymphocytic Leukemia
Item
diagnosis of chronic lymphocytic leukemia (cll)
boolean
C0023434 (UMLS CUI [1])
Advanced disease | Progressive Disease | Sign or Symptom Quantity
Item
advanced or progressive disease with ≥ 2 active clinical signs
boolean
C0679246 (UMLS CUI [1])
C1335499 (UMLS CUI [2])
C3540840 (UMLS CUI [3,1])
C1265611 (UMLS CUI [3,2])
Client Characteristics
Item
patient characteristics:
boolean
C0815172 (UMLS CUI [1])
Fertility Contraceptive methods
Item
fertile patients must use adequate contraception
boolean
C0015895 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Exclusion Criteria | Coombs Test Positive | Signs Hemolysis
Item
no positive coomb's test with signs of hemolysis
boolean
C0680251 (UMLS CUI [1])
C0009961 (UMLS CUI [2,1])
C1514241 (UMLS CUI [2,2])
C0311392 (UMLS CUI [3,1])
C0019054 (UMLS CUI [3,2])
Exclusion Communicable Disease
Item
no active infection
boolean
C2828389 (UMLS CUI [1,1])
C0009450 (UMLS CUI [1,2])
Exclusion Disease Severe Uncontrolled
Item
no uncontrolled severe disease
boolean
C2828389 (UMLS CUI [1,1])
C0012634 (UMLS CUI [1,2])
C0205082 (UMLS CUI [1,3])
C0205318 (UMLS CUI [1,4])
Exclusion Criteria | Hypersensitivity Murine-Derived Monoclonal Antibodies | Anaphylaxis Murine-Derived Monoclonal Antibodies | Hypersensitivity Murine protein | Anaphylaxis Murine protein
Item
no known hypersensitivity or anaphylactic reactions to murine antibodies or proteins
boolean
C0680251 (UMLS CUI [1])
C0020517 (UMLS CUI [2,1])
C2916903 (UMLS CUI [2,2])
C0002792 (UMLS CUI [3,1])
C2916903 (UMLS CUI [3,2])
C0020517 (UMLS CUI [4,1])
C1699668 (UMLS CUI [4,2])
C0002792 (UMLS CUI [5,1])
C1699668 (UMLS CUI [5,2])
Exclusion Cancer Other | Exception Malignant Neoplasms Treated
Item
no other malignancies within the past 2 years except for adequately treated malignancies
boolean
C2828389 (UMLS CUI [1,1])
C1707251 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0006826 (UMLS CUI [2,2])
C1522326 (UMLS CUI [2,3])
Exclusion Traumatic injury
Item
no significant traumatic injury within the past 4 weeks
boolean
C2828389 (UMLS CUI [1,1])
C3263723 (UMLS CUI [1,2])
Exclusion Criteria | Medical condition Limiting Protocol Compliance | Mental condition Limiting Protocol Compliance
Item
no coexisting medical or psychological condition that would limit study compliance
boolean
C0680251 (UMLS CUI [1])
C3843040 (UMLS CUI [2,1])
C0439801 (UMLS CUI [2,2])
C0525058 (UMLS CUI [2,3])
C3840291 (UMLS CUI [3,1])
C0439801 (UMLS CUI [3,2])
C0525058 (UMLS CUI [3,3])
Therapeutic procedure
Item
prior concurrent therapy:
boolean
C0087111 (UMLS CUI [1])
ID.13
Item
see disease characteristics
boolean
Exclusion Prior Therapy Chronic Lymphocytic Leukemia
Item
no prior treatment for cll
boolean
C2828389 (UMLS CUI [1,1])
C1514463 (UMLS CUI [1,2])
C0023434 (UMLS CUI [1,3])
Exclusion Major surgery
Item
no major surgery within the past 4 weeks
boolean
C2828389 (UMLS CUI [1,1])
C0679637 (UMLS CUI [1,2])
Exclusion Prior Chemotherapy
Item
no prior chemotherapy
boolean
C2828389 (UMLS CUI [1,1])
C1514457 (UMLS CUI [1,2])