Essential Hypertension Mild | Essential Hypertension Moderate | Sitting diastolic blood pressure | Difference Sitting diastolic blood pressure Measurement
Item
mild to moderate essential hypertension : sitting diastolic blood pressure measured at placebo visit and baseline are 90~109mmhg inclusive and the difference between sitting diastolic blood pressures measured at placebo visit and baseline(day0) is under 7mmhg.
boolean
C0085580 (UMLS CUI [1,1])
C2945599 (UMLS CUI [1,2])
C0085580 (UMLS CUI [2,1])
C0205081 (UMLS CUI [2,2])
C1319894 (UMLS CUI [3])
C1705242 (UMLS CUI [4,1])
C1319894 (UMLS CUI [4,2])
C0242485 (UMLS CUI [4,3])
Informed Consent
Item
subjects who agree to participate in this sudy and give written informed consent
boolean
C0021430 (UMLS CUI [1])
Protocol Compliance
Item
subjects considered to understand the study, be cooperative, and able to be followed-up until the end of the study
boolean
C0525058 (UMLS CUI [1])
Sitting diastolic blood pressure | Hypertension, severe | Sitting systolic blood pressure | Secondary hypertension
Item
the sitting dbp is less than 89mmhg or more than 110mmhg or severe hypertensive patient with sitting systolic blood pressure over 200mmhg patients with secondary hypertension
boolean
C1319894 (UMLS CUI [1])
C4013784 (UMLS CUI [2])
C1319893 (UMLS CUI [3])
C0155616 (UMLS CUI [4])
Kidney Disease Severe | Serum creatinine raised | Gastrointestinal Disease Severe | Hematological Disease Severe | Liver disease Severe | Aspartate aminotransferase increased | Alanine aminotransferase increased | Disease Severe Affecting Drug absorption | Disease Severe Affecting Drug disposition | Disease Severe Affecting Drug metabolism | Disease Severe Affecting Drug elimination
Item
patients with severe renal(creatinine more 1.5 times than upper limit of normal), gastrointestinal, hematological or hepatic(ast, alt more 2 twice more than upper limit of normal)disease etc. which might affect absorption, disposition, metabolism or excretion of the drug
boolean
C0022658 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0700225 (UMLS CUI [2])
C0017178 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
C0018939 (UMLS CUI [4,1])
C0205082 (UMLS CUI [4,2])
C0023895 (UMLS CUI [5,1])
C0205082 (UMLS CUI [5,2])
C0151904 (UMLS CUI [6])
C0151905 (UMLS CUI [7])
C0012634 (UMLS CUI [8,1])
C0205082 (UMLS CUI [8,2])
C0392760 (UMLS CUI [8,3])
C0678745 (UMLS CUI [8,4])
C0012634 (UMLS CUI [9,1])
C0205082 (UMLS CUI [9,2])
C0392760 (UMLS CUI [9,3])
C0678755 (UMLS CUI [9,4])
C0012634 (UMLS CUI [10,1])
C0205082 (UMLS CUI [10,2])
C0392760 (UMLS CUI [10,3])
C0683140 (UMLS CUI [10,4])
C0012634 (UMLS CUI [11,1])
C0205082 (UMLS CUI [11,2])
C0392760 (UMLS CUI [11,3])
C0683141 (UMLS CUI [11,4])
Hypotension, Orthostatic
Item
patients with postural hypotension
boolean
C0020651 (UMLS CUI [1])
Insulin-Dependent Diabetes Mellitus Severe | Diabetic - poor control | Hemoglobin A1c measurement | Oral hypoglycemic Therapy change | Insulin regime
Item
patients with sever insulin dependent diabetes mellitus or uncontrolled diabetes mellitus(hba1c>9%, regimen change of oral hypoglycemic agents within 12weeks, treated insulin before screening)
boolean
C0011854 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0421258 (UMLS CUI [2])
C0474680 (UMLS CUI [3])
C0359086 (UMLS CUI [4,1])
C3665894 (UMLS CUI [4,2])
C0557978 (UMLS CUI [5])
Myocardial Infarction | Coronary Artery Disease Severe | Heart failure | Valvular defects
Item
patients with a history of myocardial infarction, severe coronary artery disease or clinically significant heart failure or valvular defect in last 6 months
boolean
C0027051 (UMLS CUI [1])
C1956346 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
C0018801 (UMLS CUI [3])
C2748945 (UMLS CUI [4])
Tuberculosis, Pulmonary | Autoimmune Disease | Connective Tissue Disease
Item
patients with consumptive disease, autoimmune disease, connective tissue disease
boolean
C0041327 (UMLS CUI [1])
C0004364 (UMLS CUI [2])
C0009782 (UMLS CUI [3])
Hepatitis B | Hepatitis C | Hepatitis B carrier | Hepatitis C carrier
Item
patients with a history of type b or c hepatitis(include carrier)
boolean
C0019163 (UMLS CUI [1])
C0019196 (UMLS CUI [2])
C0262505 (UMLS CUI [3])
C0400920 (UMLS CUI [4])
HIV Infection | Hepatitis
Item
patients with hiv or hepatitis
boolean
C0019693 (UMLS CUI [1])
C0019158 (UMLS CUI [2])
Laboratory test result abnormal
Item
patients with clinically significant laboratory abnormality
boolean
C0438215 (UMLS CUI [1])
Pharmaceutical Preparations Affecting Blood Pressure | Therapeutic procedure Influence Blood Pressure
Item
patients receiving any drugs known to affect blood pressure or medical treatments that can influence the blood pressure
boolean
C0013227 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0005823 (UMLS CUI [1,3])
C0087111 (UMLS CUI [2,1])
C4054723 (UMLS CUI [2,2])
C0005823 (UMLS CUI [2,3])
Allergy to angiotensin II receptor antagonist | Medical contraindication Angiotensin II receptor antagonist
Item
patients with allergy or contraindication to any angiotensin ii receptor antagonists
boolean
C2585204 (UMLS CUI [1])
C1301624 (UMLS CUI [2,1])
C0521942 (UMLS CUI [2,2])
Childbearing Potential Hysterectomy Absent | Childbearing Potential Postmenopausal state Absent
Item
female of childbearing potential who does not undergo hysterectomy or is not post-menopausal
boolean
C3831118 (UMLS CUI [1,1])
C0020699 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
C3831118 (UMLS CUI [2,1])
C0232970 (UMLS CUI [2,2])
C0332197 (UMLS CUI [2,3])
Substance Use Disorders
Item
patients judged to have a history of alcohol or drug abuse by the investigator
boolean
C0038586 (UMLS CUI [1])
Study Subject Participation Status | Other Reason Study Subject Participation Status Inappropriate
Item
patients participated other clinical trial 12 weeks before screening patients judged to be inappropriate for this study by the investigator with other reasons
boolean
C2348568 (UMLS CUI [1])
C3840932 (UMLS CUI [2,1])
C2348568 (UMLS CUI [2,2])
C1548788 (UMLS CUI [2,3])