Indication Cardiac Resynchronization Therapy | Indication CRT-D System
Item
study participant with an approved indication for a crt or crt-d system.
boolean
C3146298 (UMLS CUI [1,1])
C1167956 (UMLS CUI [1,2])
C3146298 (UMLS CUI [2,1])
C1736558 (UMLS CUI [2,2])
Heart failure New York Heart Association Classification | Unresponsive to Pharmacotherapy
Item
1. new york heart association (nyha) class ii, iii, or iv heart failure unresponsive to drug therapy.
boolean
C0018801 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
C0205269 (UMLS CUI [2,1])
C0013216 (UMLS CUI [2,2])
Cardiac ejection fraction
Item
2. ef < 35%.
boolean
C0232174 (UMLS CUI [1])
QRS duration
Item
3. qrs width > 120 ms.
boolean
C0429025 (UMLS CUI [1])
Therapeutic procedure Optimal | Angiotensin-Converting Enzyme Inhibitors | Angiotensin II receptor antagonist | Adrenergic beta-1 Receptor Antagonists | Diuretics
Item
study participant receiving optimal medical therapy including ace inhibitor or angiotensin receptor blocker (arb), beta-blocker, and diuretic.
boolean
C0087111 (UMLS CUI [1,1])
C2698651 (UMLS CUI [1,2])
C0003015 (UMLS CUI [2])
C0521942 (UMLS CUI [3])
C0304516 (UMLS CUI [4])
C0012798 (UMLS CUI [5])
Congestive decompensation Events
Item
study participants with a history of significant congestive decompensation events within the last 12 months.
boolean
C1394786 (UMLS CUI [1,1])
C0441471 (UMLS CUI [1,2])
Heart failure New York Heart Association Classification
Item
nyha class i heart failure.
boolean
C0018801 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
Comorbidity Limiting Life Expectancy | Malignant Neoplasms
Item
co morbidities (e.g., cancer), which may limit lifespan < 6 months.
boolean
C0009488 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0023671 (UMLS CUI [1,3])
C0006826 (UMLS CUI [2])
Severe aortic stenosis Valve area
Item
severe aortic stenosis (valve area < 1.0 cm2).
boolean
C3806272 (UMLS CUI [1,1])
C0428817 (UMLS CUI [1,2])
Cardiac Surgery procedures | Intervention cardiac | Coronary Artery Bypass Surgery | Valve Operative Surgical Procedures | Angioplasty | Arthrectomy
Item
study participants that received cardiac surgery or intervention (i.e. coronary artery bypass grafting (cabg), valve surgery, angioplasty, arthrectomy) within the preceding 90 days.
boolean
C0018821 (UMLS CUI [1])
C0184661 (UMLS CUI [2,1])
C0018787 (UMLS CUI [2,2])
C0010055 (UMLS CUI [3])
C1186983 (UMLS CUI [4,1])
C0543467 (UMLS CUI [4,2])
C0162577 (UMLS CUI [5])
C0185244 (UMLS CUI [6])
Moderate chronic obstructive pulmonary disease | Severe chronic obstructive pulmonary disease | Patient need for Oxygen Therapy chronic | Hospitalization Chronic Obstructive Airway Disease Flare-up
Item
study participants with moderate to severe chronic obstructive pulmonary disease (copd), defined as needing chronic oxygen therapy or recent hospitalization (within 30 days) for copd flare up.
boolean
C0730605 (UMLS CUI [1])
C0730607 (UMLS CUI [2])
C0686904 (UMLS CUI [3,1])
C0184633 (UMLS CUI [3,2])
C0205191 (UMLS CUI [3,3])
C0019993 (UMLS CUI [4,1])
C0024117 (UMLS CUI [4,2])
C3830105 (UMLS CUI [4,3])
Pregnancy
Item
concurrent pregnancy.
boolean
C0032961 (UMLS CUI [1])
Primary pulmonary hypertension
Item
study participants with primary pulmonary hypertension.
boolean
C0152171 (UMLS CUI [1])
Infusion procedures Continuous Heart failure | Infusion procedures Intermittent Heart failure
Item
study participants on continuous or intermittent infusion therapy for heart failure.
boolean
C0574032 (UMLS CUI [1,1])
C0549178 (UMLS CUI [1,2])
C0018801 (UMLS CUI [1,3])
C0574032 (UMLS CUI [2,1])
C0205267 (UMLS CUI [2,2])
C0018801 (UMLS CUI [2,3])