Age
Item
age greater than 18 years
boolean
C0001779 (UMLS CUI [1])
Chronic heart failure | Cardiac ejection fraction Echocardiography | Cardiac ejection fraction Nuclear Stress Test | Cardiac ejection fraction Cardiac Catheterization
Item
diagnosis of chronic heart failure with an ejection fraction less than or equal to 45% per either an echocardiogram, nuclear cardiolyte stress test, or cardiac catheterization performed within the past 6 months.
boolean
C0264716 (UMLS CUI [1])
C0232174 (UMLS CUI [2,1])
C0013516 (UMLS CUI [2,2])
C0232174 (UMLS CUI [3,1])
C2825165 (UMLS CUI [3,2])
C0232174 (UMLS CUI [4,1])
C0018795 (UMLS CUI [4,2])
New York Heart Association Classification
Item
new york heart association functional class iii
boolean
C1275491 (UMLS CUI [1])
Therapeutic procedure Optimal Heart failure | Angiotensin-Converting Enzyme Inhibitors | Adrenergic beta-1 Receptor Antagonists | Rationale Variation | Intolerance | Medical contraindication | Patient Preference
Item
must be on optimal heart failure therapy according to aha/acc heart failure guidelines, including treatment with acei and beta-blocker therapy, or have documented rationale for variation, including intolerance, contraindication, patient preference, or personal physician's judgment
boolean
C0087111 (UMLS CUI [1,1])
C2698651 (UMLS CUI [1,2])
C0018801 (UMLS CUI [1,3])
C0003015 (UMLS CUI [2])
C0304516 (UMLS CUI [3])
C2699007 (UMLS CUI [4,1])
C0205419 (UMLS CUI [4,2])
C1744706 (UMLS CUI [5])
C1301624 (UMLS CUI [6])
C0376409 (UMLS CUI [7])
Comorbidity Interferes with Exercise testing | Behavior problem Interferes with Exercise testing | Comorbidity Preventing Completion of clinical trial | Behavior problem Preventing Completion of clinical trial
Item
comorbid disease or behavioral or other limitations that: 1) interfere with performing exercise test, or 2) prevent completion of 12 week study
boolean
C0009488 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0015260 (UMLS CUI [1,3])
C0233514 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C0015260 (UMLS CUI [2,3])
C0009488 (UMLS CUI [3,1])
C1292733 (UMLS CUI [3,2])
C2732579 (UMLS CUI [3,3])
C0233514 (UMLS CUI [4,1])
C1292733 (UMLS CUI [4,2])
C2732579 (UMLS CUI [4,3])
Pregnancy | Pregnancy, Planned
Item
currently pregnant or intent to become pregnant in the next 12 weeks or currently breastfeeding.
boolean
C0032961 (UMLS CUI [1])
C0032992 (UMLS CUI [2])
Cardiovascular event Major | Cardiovascular procedures Major
Item
major cardiovascular event or cardiovascular procedure within the prior 6 weeks
boolean
C1320716 (UMLS CUI [1,1])
C0205164 (UMLS CUI [1,2])
C0189573 (UMLS CUI [2,1])
C0205164 (UMLS CUI [2,2])
Chronic Obstructive Airway Disease | Reactive airway disease
Item
history of chronic obstructive pulmonary disease or reactive airway disease
boolean
C0024117 (UMLS CUI [1])
C3714497 (UMLS CUI [2])
Hypersensitivity Sildenafil
Item
known hypersensitivity to sildenafil
boolean
C0020517 (UMLS CUI [1,1])
C0529793 (UMLS CUI [1,2])
Cytochrome P450 3A4 Inhibitor | Ritonavir | Ketoconazole | Itraconazole
Item
current use of medications known to be a potent inhibitor of cyp3a4 (e.g., ritonavir, ketoconazole, itraconazole)
boolean
C3830624 (UMLS CUI [1])
C0292818 (UMLS CUI [2])
C0022625 (UMLS CUI [3])
C0064113 (UMLS CUI [4])
Organic nitrates | Isosorbide Dinitrate | Nitroglycerin Sublingual Product
Item
current or recent (within 6 months) use of organic nitrate medications (e.g. isosorbide dinitrate, sublingual nitroglycerin)
boolean
C3654024 (UMLS CUI [1])
C0022252 (UMLS CUI [2])
C3466369 (UMLS CUI [3])
Pulmonary Veno-Occlusive Disease | Nonarteritic anterior ischemic optic neuropathy
Item
known diagnosis of pulmonary veno-occlusive disease or non-arteritic anterior ischemic optic neuropathy
boolean
C0034091 (UMLS CUI [1])
C1852242 (UMLS CUI [2])