Age | Percutaneous Coronary Intervention
Item
1. patients older than age 18 to undergo pci
boolean
C0001779 (UMLS CUI [1])
C1532338 (UMLS CUI [2])
clopidogrel | Pretreatment Percutaneous Coronary Intervention
Item
2. pretreatment at least 6 hours before pci with clopidogrel according to the pci guidelines.
boolean
C0070166 (UMLS CUI [1])
C3539076 (UMLS CUI [2,1])
C1532338 (UMLS CUI [2,2])
Informed Consent | Informed Consent Patient Representative
Item
3. informed, written consent by the patient or her/his legally-authorized representative for participation in the study.
boolean
C0021430 (UMLS CUI [1])
C0021430 (UMLS CUI [2,1])
C0030701 (UMLS CUI [2,2])
ST segment elevation myocardial infarction
Item
1. recent st-elevation myocardial infarction within the last 48 hours.
boolean
C1536220 (UMLS CUI [1])
chronic total occlusion of coronary artery Treatment required for
Item
2. chronic coronary artery occlusion to be treated
boolean
C1955779 (UMLS CUI [1,1])
C0332121 (UMLS CUI [1,2])
Malignant Neoplasms | Comorbidity | Liver disease Severe | Kidney Disease Severe | Pancreatic Disease Severe | Life Expectancy | Protocol Compliance Unable
Item
3. malignancies or other comorbid conditions (for example severe liver, renal and pancreatic disease) with life expectancy less than one year or that may result in protocol non-compliance.
boolean
C0006826 (UMLS CUI [1])
C0009488 (UMLS CUI [2])
C0023895 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
C0022658 (UMLS CUI [4,1])
C0205082 (UMLS CUI [4,2])
C0030286 (UMLS CUI [5,1])
C0205082 (UMLS CUI [5,2])
C0023671 (UMLS CUI [6])
C0525058 (UMLS CUI [7,1])
C1299582 (UMLS CUI [7,2])
Hemorrhage | Bleeding tendency | Operative Surgical Procedures
Item
4. active bleeding, bleeding diathesis, recent surgery (< 15 days)
boolean
C0019080 (UMLS CUI [1])
C1458140 (UMLS CUI [2])
C0543467 (UMLS CUI [3])
Gastrointestinal Hemorrhage | Genitourinary tract hemorrhage
Item
5. history of gastrointestinal or genitourinary bleeding within the last 6 weeks
boolean
C0017181 (UMLS CUI [1])
C0919591 (UMLS CUI [2])
Unfractionated Heparin | Heparin, Low-Molecular-Weight
Item
6. treatment with ufh within 6 hours or low-molecular weight heparin within 8 hours before randomization.
boolean
C2825026 (UMLS CUI [1])
C0019139 (UMLS CUI [2])
bivalirudin
Item
7. treatment with bivalirudin within 24 hours beforerandomization.
boolean
C0168273 (UMLS CUI [1])
Uncontrolled hypertension Severe Unresponsive to Treatment
Item
8. severe uncontrolled hypertension >180/110 mmhg unresponsive to therapy
boolean
C1868885 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0205269 (UMLS CUI [1,3])
Hematology finding abnormal | Hemoglobin measurement | Platelet Count measurement
Item
9. relevant hematologic deviations: hemoglobin < 100 g/l or platelet count < 100 x 109
boolean
C0475182 (UMLS CUI [1])
C0518015 (UMLS CUI [2])
C0032181 (UMLS CUI [3])
Glomerular Filtration Rate | Creatinine measurement, serum | Dependence on renal dialysis
Item
10. glomerular filtration rate (gfr) < 30 ml/min or serum creatinine > 30 mg/l or dependence on renal dialysis.
boolean
C0017654 (UMLS CUI [1])
C0201976 (UMLS CUI [2])
C0524376 (UMLS CUI [3])
Hypersensitivity Investigational New Drugs | Aspirin allergy | Hypersensitivity clopidogrel | Hypersensitivity Unfractionated Heparin | Hypersensitivity bivalirudin | Hypersensitivity Stainless Steel | Anaphylaxis Post Exposure to Contrast Media
Item
11. known allergy to the study medications: aspirin, clopidogrel, ufh, bivalirudin; stainless steel; true anaphylaxis after prior exposure to contrast media.
boolean
C0020517 (UMLS CUI [1,1])
C0013230 (UMLS CUI [1,2])
C0004058 (UMLS CUI [2])
C0020517 (UMLS CUI [3,1])
C0070166 (UMLS CUI [3,2])
C0020517 (UMLS CUI [4,1])
C2825026 (UMLS CUI [4,2])
C0020517 (UMLS CUI [5,1])
C0168273 (UMLS CUI [5,2])
C0020517 (UMLS CUI [6,1])
C0038126 (UMLS CUI [6,2])
C0002792 (UMLS CUI [7,1])
C0687676 (UMLS CUI [7,2])
C0332157 (UMLS CUI [7,3])
C0009924 (UMLS CUI [7,4])
Heparin-induced thrombocytopenia
Item
12. known heparin-induced thrombocytopenia
boolean
C0272285 (UMLS CUI [1])