Exclusion criteria
Other lymphoma
boolean
CNS involvement
boolean
Pregnancy
boolean
e.g. uncontrolled arterial hypertension, heart failure (NYHA III-IV), uncontrolled diabetes mellitus, pulmonary fibrosis, uncontrolled hyperlipoproteinaemia
boolean
Myocardial infarction within the last 6 months
boolean
Active uncontrolled infections
boolean
Vaccination
boolean
Mental status
boolean
CD20 negativity
boolean
Except: adequately treated nonmelanoma skin cancer, curatively treated in-situ cancer of the Cervix, DCIS of the breast, or other solid tumors curatively treated with no evidence of disease for >3 years, or prostate cancer with a life expectancy of more than 2 years
boolean
Any agents must have been stoppped at least 2 weeks prior to day 1 of GOAL treatment and all treatment-related adverse events must have returned to Grade 1.
boolean
exposition to Obinutuzumab or Pixantrone
boolean
hypersensitivity to medicinal products
boolean
Concurrent participation in non-treatment studies is not excluded.
boolean
Medical or psychological conditions
boolean