Age
Item
1. age at diagnosis at 1 to 18 years.
boolean
C0001779 (UMLS CUI [1])
Induction Therapy
Item
2. the start of induction therapy within a time interval of study recruitment phase.
boolean
C0600558 (UMLS CUI [1])
Acute lymphocytic leukemia | Bone marrow tumor cells Analysis morphological | Bone marrow tumor cells Cytochemical test | Bone marrow tumor cells Immunologic analysis
Item
3. the diagnosis of all is to be proved by the morphological, cytochemical, and immunological analysis of tumor cells in bone marrow.
boolean
C0023449 (UMLS CUI [1])
C0238805 (UMLS CUI [2,1])
C0002778 (UMLS CUI [2,2])
C0543482 (UMLS CUI [2,3])
C0238805 (UMLS CUI [3,1])
C0201825 (UMLS CUI [3,2])
C0238805 (UMLS CUI [4,1])
C3516449 (UMLS CUI [4,2])
Informed Consent Parent | Informed Consent Guardian
Item
4. informed consent of the parents (guardians) of the patient to be treated in one of the clinics included in this multicenter study.
boolean
C0021430 (UMLS CUI [1,1])
C0030551 (UMLS CUI [1,2])
C0021430 (UMLS CUI [2,1])
C1274041 (UMLS CUI [2,2])
Acute lymphocytic leukemia Second malignancy
Item
1. all is a second malignant tumor;
boolean
C0023449 (UMLS CUI [1,1])
C0085183 (UMLS CUI [1,2])
Recurrent disease | Acute lymphocytic leukemia Misdiagnosis | Acute lymphocytic leukemia Treated Inadequate
Item
2. the disease is a relapse of previously misdiagnosed and, therefore, inadequately treated all;
boolean
C0277556 (UMLS CUI [1])
C0023449 (UMLS CUI [2,1])
C0679838 (UMLS CUI [2,2])
C0023449 (UMLS CUI [3,1])
C1522326 (UMLS CUI [3,2])
C0205412 (UMLS CUI [3,3])
Comorbidity Severe Preventing Chemotherapy Regimen | Multiple system malformation syndrome | Heart Diseases | Metabolic Diseases
Item
3. there is severe concomitant disease, which significantly impedes chemotherapy protocol (such as multiple malformations, heart diseases, metabolic disorders, etc.);
boolean
C0009488 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C1292733 (UMLS CUI [1,3])
C0392920 (UMLS CUI [1,4])
C0265198 (UMLS CUI [2])
C0018799 (UMLS CUI [3])
C0025517 (UMLS CUI [4])
Cytostatic chemotherapy | Data Basic Lacking | Acute lymphocytic leukemia Differential Diagnosis Unsuccessful | Acute Myelocytic Leukemia Differential Diagnosis Unsuccessful | Risk Group Stratification Unsuccessful
Item
4. there is a lack of important basic data needed for the exact adherence to the cytostatic therapy according to a specific protocol of chemotherapy (differential diagnosis of acute lymphoblastic/myeloid leukemia is not possible, stratification according to risk group is not possible);
boolean
C2609342 (UMLS CUI [1])
C1511726 (UMLS CUI [2,1])
C1527178 (UMLS CUI [2,2])
C0332268 (UMLS CUI [2,3])
C0023449 (UMLS CUI [3,1])
C0011906 (UMLS CUI [3,2])
C1272705 (UMLS CUI [3,3])
C0023467 (UMLS CUI [4,1])
C0011906 (UMLS CUI [4,2])
C1272705 (UMLS CUI [4,3])
C0035647 (UMLS CUI [5,1])
C0441833 (UMLS CUI [5,2])
C1514983 (UMLS CUI [5,3])
C1272705 (UMLS CUI [5,4])
Cytotoxic agent
Item
5. the patient was treated before for a long time with cytotoxic drugs;
boolean
C0304497 (UMLS CUI [1])
Therapeutic procedure Protocol Deviation | Therapeutic procedure Deviation Independent of Adverse effects | Therapeutic procedure Deviation Independent of Disease complication
Item
6. there were deviations in the treatment not covered by the protocol and/or not due to side effects of treatment and/or complications of the disease
boolean
C0087111 (UMLS CUI [1,1])
C1705236 (UMLS CUI [1,2])
C0087111 (UMLS CUI [2,1])
C0205419 (UMLS CUI [2,2])
C0332291 (UMLS CUI [2,3])
C0879626 (UMLS CUI [2,4])
C0087111 (UMLS CUI [3,1])
C0205419 (UMLS CUI [3,2])
C0332291 (UMLS CUI [3,3])
C0544688 (UMLS CUI [3,4])