Primary central nervous system lymphoma
Item
histologically confirmed newly diagnosed primary cns lymphoma (pcnsl)
boolean
C0280803 (UMLS CUI [1])
Disease untreated
Item
previously untreated disease
boolean
C0012634 (UMLS CUI [1,1])
C0332155 (UMLS CUI [1,2])
Diffuse Large B-Cell Lymphoma
Item
diffuse large b-cell lymphoma histology
boolean
C0079744 (UMLS CUI [1])
Methotrexate Dose
Item
must be clinically eligible to receive standard 3 g/m² methotrexate if outside trial
boolean
C0025677 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
Effusion Absent | Edema Absent
Item
no clinically significant effusions or edema
boolean
C0013687 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0013604 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Client Characteristics
Item
patient characteristics:
boolean
C0815172 (UMLS CUI [1])
ECOG performance status
Item
ecog performance status 0-3
boolean
C1520224 (UMLS CUI [1])
Neutrophil count
Item
neutrophils ≥ 1 x 10^9/l
boolean
C0200633 (UMLS CUI [1])
Platelet Count measurement
Item
platelet count ≥ 100 x 10^9/l
boolean
C0032181 (UMLS CUI [1])
Serum total bilirubin measurement
Item
bilirubin < 1.5 times upper limit of normal
boolean
C1278039 (UMLS CUI [1])
Glomerular Filtration Rate EDTA Method
Item
glomerular filtration rate (initially measured by edta/isotope method) ≥ 50 ml/min
boolean
C0017654 (UMLS CUI [1,1])
C0013618 (UMLS CUI [1,2])
C0025663 (UMLS CUI [1,3])
Pregnancy Absent | Breast Feeding Absent
Item
not pregnant or nursing
boolean
C0032961 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0006147 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Pregnancy test negative
Item
negative pregnancy test
boolean
C0427780 (UMLS CUI [1])
Fertility Contraceptive methods
Item
fertile patients must use effective contraception during and for 6 months after completion of study therapy
boolean
C0015895 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
HIV Seropositivity
Item
hiv positivity
boolean
C0019699 (UMLS CUI [1])
Dementia | Neurological Dysfunction | Primary central nervous system lymphoma Uninvolved
Item
dementia or neurological dysfunction not considered to be due to the pcnsl
boolean
C0497327 (UMLS CUI [1])
C1709219 (UMLS CUI [2])
C0280803 (UMLS CUI [3,1])
C0205429 (UMLS CUI [3,2])
Medical condition Serious | Medical condition Uncontrolled
Item
other serious or uncontrolled medical conditions
boolean
C3843040 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C3843040 (UMLS CUI [2,1])
C0205318 (UMLS CUI [2,2])
Cancer Other | Exception Skin carcinoma Treated | Exception Carcinoma in Situ Treated
Item
prior malignancy, except adequately treated nonmelanoma skin cancer or carcinoma in situ
boolean
C1707251 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0699893 (UMLS CUI [2,2])
C1522326 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C0007099 (UMLS CUI [3,2])
C1522326 (UMLS CUI [3,3])
Therapeutic procedure
Item
prior concurrent therapy:
boolean
C0087111 (UMLS CUI [1])
Cytotoxic Chemotherapy
Item
no prior cytotoxic chemotherapy
boolean
C0677881 (UMLS CUI [1])
Prophylactic antibiotic
Item
no concurrent prophylactic antibiotics
boolean
C0362063 (UMLS CUI [1])
co-trimoxazole
Item
no concurrent co-trimoxazole
boolean
C0041044 (UMLS CUI [1])