Age | Pregnancy Absent | Ethnicity Any
Item
1. the volunteer (male or non-pregnant female, any ethnicity) must be > 18 years of age.
boolean
C0001779 (UMLS CUI [1])
C0032961 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0015031 (UMLS CUI [3,1])
C1552551 (UMLS CUI [3,2])
Atherosclerosis Absent | Carotid Artery Disease Absent | Peripheral Arterial Disease Absent | Coronary Artery Disease Absent
Item
2. the volunteer has no history of a physician diagnosis of atherosclerosis such as carotid, peripheral, or coronary artery disease (cad).
boolean
C0004153 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0007273 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C1704436 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
C1956346 (UMLS CUI [4,1])
C0332197 (UMLS CUI [4,2])
Pulmonary Embolism Absent | Myocardial Infarction Absent | Cerebrovascular accident Absent
Item
3. the volunteer has no history of a physician diagnosis of pulmonary embolism (pe), mi, or stroke.
boolean
C0034065 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0027051 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0038454 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
Informed Consent
Item
4. the volunteer must sign a written informed consent, prior to the procedure, using a form that is approved by the local institutional review board.
boolean
C0021430 (UMLS CUI [1])
Diabetes Mellitus
Item
1. a diagnosis if diabetes mellitus.
boolean
C0011849 (UMLS CUI [1])
Pharmaceutical Preparations Limitation ignored | Supplements Limitation ignored | Food Limitation ignored
Item
2. the limitations for specific medications, supplements and food items are exceeded as follows:
boolean
C0013227 (UMLS CUI [1,1])
C0449295 (UMLS CUI [1,2])
C1554079 (UMLS CUI [1,3])
C0242295 (UMLS CUI [2,1])
C0449295 (UMLS CUI [2,2])
C1554079 (UMLS CUI [2,3])
C0016452 (UMLS CUI [3,1])
C0449295 (UMLS CUI [3,2])
C1554079 (UMLS CUI [3,3])
Pharmaceutical Preparations Dose Quantity Frequency | Supplements Dose Quantity Frequency
Item
more than 1 normal dose of the following medications and/or supplements once a week during the 3 months prior to enrollment:
boolean
C0013227 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C0439603 (UMLS CUI [1,4])
C0242295 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
C0439603 (UMLS CUI [2,4])
Aspirin | Ibuprofen | Fish oil Extract
Item
aspirin • ibuprofen • fish-oil extracts
boolean
C0004057 (UMLS CUI [1])
C0020740 (UMLS CUI [2])
C0556145 (UMLS CUI [3,1])
C1705851 (UMLS CUI [3,2])
Antioxidants | Vitamins
Item
antioxidants • vitamins
boolean
C0003402 (UMLS CUI [1])
C0042890 (UMLS CUI [2])
Serving Normal Quantity Weekly
Item
more than 1 normal serving per week in the 3 months prior to enrollment:
boolean
C1519269 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C0332174 (UMLS CUI [1,4])
Grape juice | Tea | Wine
Item
other grape juices • tea • wine
boolean
C0452455 (UMLS CUI [1])
C0039400 (UMLS CUI [2])
C0043188 (UMLS CUI [3])
Beer | Alcoholic drinks | Grapes
Item
beer • alcoholic drinks • grapes
boolean
C0004922 (UMLS CUI [1])
C0001967 (UMLS CUI [2])
C0018208 (UMLS CUI [3])
Serving Combination Quantity per day
Item
more than 5 servings per day in any combination in the 7 days (1 weeks prior to enrollment:
boolean
C1519269 (UMLS CUI [1,1])
C0205195 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C0439505 (UMLS CUI [1,4])
Juice Except for Grape juice | Garlic | Broccoli
Item
non-grape juices • garlic • broccoli
boolean
C1268568 (UMLS CUI [1,1])
C0332300 (UMLS CUI [1,2])
C0452455 (UMLS CUI [1,3])
C0993630 (UMLS CUI [2])
C0330499 (UMLS CUI [3])
Apple | Berries Type Any | Onions
Item
apples • any type of berries • onions volunteer is pregnant or lactating at the time of enrollment.
boolean
C1095830 (UMLS CUI [1])
C0005135 (UMLS CUI [2,1])
C0332307 (UMLS CUI [2,2])
C1552551 (UMLS CUI [2,3])
C0029035 (UMLS CUI [3])
Exclusion Secondary
Item
secondary exclusions:
boolean
C2828389 (UMLS CUI [1,1])
C0175668 (UMLS CUI [1,2])
Use Excessive Resulting in Patient withdrawn from trial
Item
1. use of any of the above listed items during the 12 week course of study treatment will be documented and excess use 3 times or more will result in an administrative withdrawal of the volunteer from the study prior to the measurement of the next monthly platelet aggregation laboratory values (although those values will be measured for exploratory evaluation and the participant will remain under treatment until the end of the 12 week period).
boolean
C1524063 (UMLS CUI [1,1])
C0442802 (UMLS CUI [1,2])
C0332294 (UMLS CUI [1,3])
C0422727 (UMLS CUI [1,4])
Fruit Juices Regular | Fruit Serving Quantity per day | Vegetables Serving Quantity per day
Item
2. routine consumption of fruit juices, or of >5 servings per day of referenced fruits or vegetables, will result in administrative withdrawal of the participant from the study's primary aim.
boolean
C0452453 (UMLS CUI [1,1])
C0205272 (UMLS CUI [1,2])
C0016767 (UMLS CUI [2,1])
C1519269 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
C0439505 (UMLS CUI [2,4])
C0042440 (UMLS CUI [3,1])
C1519269 (UMLS CUI [3,2])
C1265611 (UMLS CUI [3,3])
C0439505 (UMLS CUI [3,4])
POMEGRANATE JUICE | POMEGRANATE JUICE Similar
Item
3. although it is unlikely the use of pgj or look alike/ taste alike (placebo) beverage will harm the pregnant or lactating woman, the dietary restrictions placed on the participant for the duration of the study may conflict with dietary recommendations for pregnant or lactating women. women of child bearing potential, therefore, will meet a secondary exclusion if they become pregnant.
boolean
C1327962 (UMLS CUI [1])
C1327962 (UMLS CUI [2,1])
C2348205 (UMLS CUI [2,2])