Non-Small Cell Lung Carcinoma Squamous TNM clinical staging | Malignant Effusion | Local Therapy | Recurrent disease
Item
histologically- or cytologically-confirmed diagnosis of squamous nsclc stage iiib with malignant effusion (fluid cytology demonstrating malignant cells required), stage iv, or recurrent disease after definitive local therapy
boolean
C0007131 (UMLS CUI [1,1])
C1182670 (UMLS CUI [1,2])
C3258246 (UMLS CUI [1,3])
C0080032 (UMLS CUI [2])
C1517925 (UMLS CUI [3])
C0277556 (UMLS CUI [4])
First line treatment | Cisplatin | gemcitabine
Item
candidate for primary treatment with cisplatin and gemcitabine
boolean
C1708063 (UMLS CUI [1])
C0008838 (UMLS CUI [2])
C0045093 (UMLS CUI [3])
Measurable Disease
Item
presence of measurable disease by recist
boolean
C1513041 (UMLS CUI [1])
Organ function | ECOG performance status
Item
adequate organ function as defined by the following criteria: ecog performance status of 0 or 1
boolean
C0678852 (UMLS CUI [1])
C1520224 (UMLS CUI [2])
Systemic therapy Non-Small Cell Lung Carcinoma TNM clinical staging | Malignant Effusion | Non-Small Cell Lung Carcinoma TNM clinical staging
Item
prior systemic treatment for stage iiib (with malignant effusion) or stage iv nsclc.
boolean
C1515119 (UMLS CUI [1,1])
C0007131 (UMLS CUI [1,2])
C3258246 (UMLS CUI [1,3])
C0080032 (UMLS CUI [2])
C0007131 (UMLS CUI [3,1])
C3258246 (UMLS CUI [3,2])
Lesion of lung Quantity | Cavitation | Lesion Blood Vessel Major CT | Lesion Blood Vessel Major MRI
Item
one or more lung lesions with cavitation, or any lesion invading or abutting a major blood vessel as assessed by ct or mri.
boolean
C0577916 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0578537 (UMLS CUI [2])
C0221198 (UMLS CUI [3,1])
C0005847 (UMLS CUI [3,2])
C0205164 (UMLS CUI [3,3])
C0040405 (UMLS CUI [3,4])
C0221198 (UMLS CUI [4,1])
C0005847 (UMLS CUI [4,2])
C0205164 (UMLS CUI [4,3])
C0024485 (UMLS CUI [4,4])
Hemoptysis Amount Duration | Hemoptysis Grade
Item
history of hemoptysis > ½ tsp (2.5 ml) of blood per day for a day or more within 1 week of study treatment, or grade 3 or 4 hemoptysis within 4 weeks of study treatment
boolean
C0019079 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0449238 (UMLS CUI [1,3])
C0019079 (UMLS CUI [2,1])
C0441800 (UMLS CUI [2,2])
Hemorrhage CTCAE Grades
Item
nci ctcae grade 3 hemorrhage from any cause within 4 weeks of study treatment
boolean
C0019080 (UMLS CUI [1,1])
C1516728 (UMLS CUI [1,2])
Uncontrolled hypertension Pre-existing | Blood pressure finding Quantity
Item
preexisting uncontrolled hypertension as documented by 2 baseline blood pressure readings taken at least 1 hour apart.
boolean
C1868885 (UMLS CUI [1,1])
C2347662 (UMLS CUI [1,2])
C1271104 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
Metastatic malignant neoplasm to brain Untreated
Item
untreated brain metastases.
boolean
C0220650 (UMLS CUI [1,1])
C0332155 (UMLS CUI [1,2])
Anticoagulation Therapy Patient need for | Aspirin Regular U/day | NSAID Regular | Platelet Inhibitors Regular
Item
need for therapeutic anticoagulation, regular use of aspirin (> 325 mg/day), nsaid or other medications known to inhibit platelet function.
boolean
C0003281 (UMLS CUI [1,1])
C0686904 (UMLS CUI [1,2])
C0004057 (UMLS CUI [2,1])
C0205272 (UMLS CUI [2,2])
C0456683 (UMLS CUI [2,3])
C0003211 (UMLS CUI [3,1])
C0205272 (UMLS CUI [3,2])
C0032188 (UMLS CUI [4,1])
C0205272 (UMLS CUI [4,2])