Advanced breast cancer | Breast cancer recurrent
Item
advanced or recurrent breast cancer
boolean
C3495917 (UMLS CUI [1])
C0278493 (UMLS CUI [2])
Resistant to Chemotherapy Anthracycline based | Resistant to Chemotherapy Taxane based | Chemotherapy Continue Difficult | Adverse effects Unacceptable
Item
resistant against anthracycline-based and taxane-based chemotherapy or difficult to continue the chemotherapy due to intolerable side effect(s)
boolean
C0332325 (UMLS CUI [1,1])
C0392920 (UMLS CUI [1,2])
C0282564 (UMLS CUI [1,3])
C1705938 (UMLS CUI [1,4])
C0332325 (UMLS CUI [2,1])
C0392920 (UMLS CUI [2,2])
C0215136 (UMLS CUI [2,3])
C1705938 (UMLS CUI [2,4])
C0392920 (UMLS CUI [3,1])
C0549178 (UMLS CUI [3,2])
C0332218 (UMLS CUI [3,3])
C0879626 (UMLS CUI [4,1])
C1883420 (UMLS CUI [4,2])
Resistant to trastuzumab | Trastuzumab Continue Difficult | HER2/Neu Positive Adverse effects Unacceptable
Item
resistant against trastuzumab or difficult to continue it due to intolerable side effect(s) when her-2 is positive
boolean
C0332325 (UMLS CUI [1,1])
C0728747 (UMLS CUI [1,2])
C0728747 (UMLS CUI [2,1])
C0549178 (UMLS CUI [2,2])
C0332218 (UMLS CUI [2,3])
C2348909 (UMLS CUI [3,1])
C0879626 (UMLS CUI [3,2])
C1883420 (UMLS CUI [3,3])
ECOG performance status
Item
ecog performance status 0-2
boolean
C1520224 (UMLS CUI [1])
Life Expectancy
Item
life expectancy > 3 months
boolean
C0023671 (UMLS CUI [1])
HLA-A*2402
Item
hla-a*2402
boolean
C1098634 (UMLS CUI [1])
Laboratory Results
Item
laboratory values as follows
boolean
C1254595 (UMLS CUI [1])
Absolute neutrophil count
Item
2000/mm3<wbc<15000/mm3
boolean
C0948762 (UMLS CUI [1])
Platelet Count measurement
Item
platelet count>100000/mm3
boolean
C0032181 (UMLS CUI [1])
Serum total bilirubin measurement
Item
bilirubin < 3.0mg/dl
boolean
C1278039 (UMLS CUI [1])
Aspartate aminotransferase measurement
Item
asparate transaminase < 150iu/l
boolean
C0201899 (UMLS CUI [1])
Alanine aminotransferase measurement
Item
alanine transaminase < 150iu/l
boolean
C0201836 (UMLS CUI [1])
Creatinine measurement, serum
Item
creatinine < 3.0mg/dl
boolean
C0201976 (UMLS CUI [1])
Informed Consent
Item
able and willing to give valid written informed consent
boolean
C0021430 (UMLS CUI [1])
Pregnancy | Childbearing Potential Contraceptive methods Refused | Childbearing Potential Contraceptive methods Unable
Item
pregnancy(woman of childbearing potential:refusal or inability to use effective means of contraception)
boolean
C0032961 (UMLS CUI [1])
C3831118 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
C1705116 (UMLS CUI [2,3])
C3831118 (UMLS CUI [3,1])
C0700589 (UMLS CUI [3,2])
C1299582 (UMLS CUI [3,3])
Breast Feeding
Item
breastfeeding
boolean
C0006147 (UMLS CUI [1])
Communicable Disease | Communicable Disease Uncontrolled
Item
active or uncontrolled infection
boolean
C0009450 (UMLS CUI [1])
C0009450 (UMLS CUI [2,1])
C0205318 (UMLS CUI [2,2])
Steroids | Immunosuppressive Agents
Item
concurrent treatment with steroids or immunosuppressing agent
boolean
C0038317 (UMLS CUI [1])
C0021081 (UMLS CUI [2])
Chemotherapy | Therapeutic radiology procedure | Immunotherapy
Item
prior chemotherapy,radiation therapy, or immunotherapy within 4 weeks
boolean
C0392920 (UMLS CUI [1])
C1522449 (UMLS CUI [2])
C0021083 (UMLS CUI [3])
Metastatic malignant neoplasm to brain Uncontrolled | Spinal metastases Uncontrolled
Item
uncontrolled brain and/or intraspinal
boolean
C0220650 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0684550 (UMLS CUI [2,1])
C0205318 (UMLS CUI [2,2])
Study Subject Participation Status Inappropriate
Item
decision of unsuitableness by principal investigator or physician-in-charge
boolean
C2348568 (UMLS CUI [1,1])
C1548788 (UMLS CUI [1,2])