Acute lymphocytic leukemia
Item
diagnosis of acute lymphoblastic leukemia
boolean
C0023449 (UMLS CUI [1])
Study Subject Participation Status
Item
enrolled on cog-aall0434 (cohort #1 only) or cog-aall0232 (cohorts #1 and #2)
boolean
C2348568 (UMLS CUI [1])
Methotrexate High dose | Methotrexate Dose Increasing
Item
patients must have received either high-dose methotrexate or escalating-dose methotrexate during interim maintenance.
boolean
C0025677 (UMLS CUI [1,1])
C0444956 (UMLS CUI [1,2])
C0025677 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0442808 (UMLS CUI [2,3])
CNS3 Disease Excluded
Item
no cns-3 disease
boolean
C3899748 (UMLS CUI [1,1])
C0012634 (UMLS CUI [1,2])
C2828389 (UMLS CUI [1,3])
Study Subject Participation Status | Recurrent Malignant Neoplasm Absent | Secondary Malignant Neoplasm Absent
Item
patients must enroll within 8-24 months after completion of therapy on cog-aall0232 and no evidence of relapsed or secondary malignancy
boolean
C2348568 (UMLS CUI [1])
C1458156 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C3266877 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
Neurodevelopmental Disorders Excluded
Item
no known significant neurodevelopmental disability unrelated to cancer diagnosis including, but not limited to, any of the following:
boolean
C1535926 (UMLS CUI [1,1])
C2828389 (UMLS CUI [1,2])
Down Syndrome Excluded
Item
down syndrome
boolean
C0013080 (UMLS CUI [1,1])
C2828389 (UMLS CUI [1,2])
Fragile X Syndrome Excluded
Item
fragile x mental retardation
boolean
C0016667 (UMLS CUI [1,1])
C2828389 (UMLS CUI [1,2])
Autistic Disorder Excluded
Item
autism
boolean
C0004352 (UMLS CUI [1,1])
C2828389 (UMLS CUI [1,2])
Pervasive Development Disorder Excluded
Item
pervasive developmental disability
boolean
C0524528 (UMLS CUI [1,1])
C2828389 (UMLS CUI [1,2])
Epilepsy Excluded
Item
seizure disorder
boolean
C0014544 (UMLS CUI [1,1])
C2828389 (UMLS CUI [1,2])
Attention deficit hyperactivity disorder | Learning Disability Specific | Dyslexia
Item
attention-deficit hyperactivity disorder or specific learning disability (e.g., dyslexia) allowed
boolean
C1263846 (UMLS CUI [1])
C0751265 (UMLS CUI [2,1])
C0205369 (UMLS CUI [2,2])
C0476254 (UMLS CUI [3])
Hypesthesia Excluded | Visual Impairment uncorrected Pre-existing Exclusion | Deafness Excluded
Item
no sensory impairment (e.g., pre-existing uncorrectable vision impairment or deafness)
boolean
C0020580 (UMLS CUI [1,1])
C2828389 (UMLS CUI [1,2])
C3665347 (UMLS CUI [2,1])
C4072785 (UMLS CUI [2,2])
C2347662 (UMLS CUI [2,3])
C2828389 (UMLS CUI [2,4])
C0011053 (UMLS CUI [3,1])
C2828389 (UMLS CUI [3,2])
Therapeutic radiology procedure cranial Exclusion
Item
no cranial radiation therapy
boolean
C1522449 (UMLS CUI [1,1])
C0037303 (UMLS CUI [1,2])
C2828389 (UMLS CUI [1,3])