Atrial Fibrillation | Treatment required for rate control
Item
have a diagnosis of atrial fibrillation in need of treatment for rate control
boolean
C0004238 (UMLS CUI [1])
C0332121 (UMLS CUI [2,1])
C0489879 (UMLS CUI [2,2])
Abstinence Anti-Arrhythmia Agents | Abstinence Pharmaceutical Preparations AV node Blocking | Exception Esmolol
Item
be able and willing to abstain from any antiarrhythmics, including atrioventricular (av) nodal blocking agents (except for esmolol per protocol), from no later than 8:00 p.m. on the day prior to dosing until completion of the last dose period assessment
boolean
C3843422 (UMLS CUI [1,1])
C0003195 (UMLS CUI [1,2])
C3843422 (UMLS CUI [2,1])
C0013227 (UMLS CUI [2,2])
C0004247 (UMLS CUI [2,3])
C0332206 (UMLS CUI [2,4])
C1705847 (UMLS CUI [3,1])
C0116569 (UMLS CUI [3,2])
Abstinence Food Containing Xanthine | Abstinence Food Containing Chocolate | Abstinence Beverages Containing Xanthine | Abstinence Beverages Containing Chocolate | Abstinence Pharmaceutical Preparations Containing Xanthine | Abstinence Pharmaceutical Preparations Containing Chocolate
Item
be able and willing to abstain from xanthine- or chocolate-containing foods, beverages, and medications
boolean
C3843422 (UMLS CUI [1,1])
C0016452 (UMLS CUI [1,2])
C0332256 (UMLS CUI [1,3])
C0043314 (UMLS CUI [1,4])
C3843422 (UMLS CUI [2,1])
C0016452 (UMLS CUI [2,2])
C0332256 (UMLS CUI [2,3])
C0008299 (UMLS CUI [2,4])
C3843422 (UMLS CUI [3,1])
C0005329 (UMLS CUI [3,2])
C0332256 (UMLS CUI [3,3])
C0043314 (UMLS CUI [3,4])
C3843422 (UMLS CUI [4,1])
C0005329 (UMLS CUI [4,2])
C0332256 (UMLS CUI [4,3])
C0008299 (UMLS CUI [4,4])
C3843422 (UMLS CUI [5,1])
C0013227 (UMLS CUI [5,2])
C0332256 (UMLS CUI [5,3])
C0043314 (UMLS CUI [5,4])
C3843422 (UMLS CUI [6,1])
C0013227 (UMLS CUI [6,2])
C0332256 (UMLS CUI [6,3])
C0008299 (UMLS CUI [6,4])
Postmenopausal state | Female Sterilization | Childbearing Potential Breast Feeding Absent | Childbearing Potential Pregnancy test negative | Childbearing Potential Planned Pregnancy Absent | Contraceptive methods
Item
females must be post-menopausal or sterilized; or if of childbearing potential, must not be breastfeeding and must have a negative pregnancy test at screening and no intention of becoming pregnant during the course of the study. males and females must be using adequate contraception during the study.
boolean
C0232970 (UMLS CUI [1])
C0015787 (UMLS CUI [2])
C3831118 (UMLS CUI [3,1])
C0006147 (UMLS CUI [3,2])
C0332197 (UMLS CUI [3,3])
C3831118 (UMLS CUI [4,1])
C0427780 (UMLS CUI [4,2])
C3831118 (UMLS CUI [5,1])
C0032992 (UMLS CUI [5,2])
C0332197 (UMLS CUI [5,3])
C0700589 (UMLS CUI [6])
Accessory cardiac pathway
Item
have a known accessory pathway
boolean
C1963785 (UMLS CUI [1])
Myocardial Ischemia | Acute Coronary Syndrome
Item
have active myocardial ischemia or recent acute coronary syndrome
boolean
C0151744 (UMLS CUI [1])
C0948089 (UMLS CUI [2])
Heart failure | Bradycardia | Second degree atrioventricular block | Complete atrioventricular block | Shock, Cardiogenic
Item
have acute or overt heart failure, bradycardia, heart block greater than first degree, or cardiogenic shock
boolean
C0018801 (UMLS CUI [1])
C0428977 (UMLS CUI [2])
C0264906 (UMLS CUI [3])
C0151517 (UMLS CUI [4])
C0036980 (UMLS CUI [5])
Esmolol allergy | Aminophylline allergy | Hypersensitivity Esmolol Constituents | Hypersensitivity Aminophylline Constituents | Medical contraindication Esmolol | Medical contraindication Aminophylline | Medical contraindication Esmolol Constituents | Medical contraindication Aminophylline Constituents
Item
have allergies or contraindications to treatment with esmolol or aminophylline, or any of their constituents
boolean
C0570888 (UMLS CUI [1])
C0571074 (UMLS CUI [2])
C0020517 (UMLS CUI [3,1])
C0116569 (UMLS CUI [3,2])
C0729650 (UMLS CUI [3,3])
C0020517 (UMLS CUI [4,1])
C0002575 (UMLS CUI [4,2])
C0729650 (UMLS CUI [4,3])
C1301624 (UMLS CUI [5,1])
C0116569 (UMLS CUI [5,2])
C1301624 (UMLS CUI [6,1])
C0002575 (UMLS CUI [6,2])
C1301624 (UMLS CUI [7,1])
C0116569 (UMLS CUI [7,2])
C0729650 (UMLS CUI [7,3])
C1301624 (UMLS CUI [8,1])
C0002575 (UMLS CUI [8,2])
C0729650 (UMLS CUI [8,3])
Lying systolic blood pressure
Item
have a supine cuff systolic blood pressure < 90 mm hg
boolean
C1319895 (UMLS CUI [1])
Theophylline | Aminophylline | Trental
Item
be undergoing treatment with theophylline/aminophylline preparations, trental®
boolean
C0039771 (UMLS CUI [1])
C0002575 (UMLS CUI [2])
C0699487 (UMLS CUI [3])
Pentoxifylline | Carbamazepine
Item
(pentoxifylline), or carbamazepine
boolean
C0030899 (UMLS CUI [1])
C0006949 (UMLS CUI [2])
Therapeutic procedure Asthma | Therapeutic procedure Reactive airway disease
Item
have asthma or other reactive airways disease currently on-treatment
boolean
C0087111 (UMLS CUI [1,1])
C0004096 (UMLS CUI [1,2])
C0087111 (UMLS CUI [2,1])
C3714497 (UMLS CUI [2,2])
Pancreatic Disease | Pancreatic Disease chronic | Serum amylase raised | Serum lipase raised
Item
have a history of an active or chronic pancreatic disease or clinically significant increased levels of serum amylase or lipase
boolean
C0030286 (UMLS CUI [1])
C0030286 (UMLS CUI [2,1])
C0205191 (UMLS CUI [2,2])
C0476327 (UMLS CUI [3])
C3670924 (UMLS CUI [4])