Schizophrenia disease length
Item
must have a clinical diagnosis of schizophrenia for at least 1 year prior to screening
boolean
C0036341 (UMLS CUI [1,1])
C0872146 (UMLS CUI [1,2])
Antipsychotic Agents | Antipsychotic Agents Change Expected | Symptoms persistent | Adverse effects continuing
Item
had been receiving treatment with antipsychotics, but is judged to be a candidate for changing antipsychotic on the basis of either persistent symptoms or continuing side effects
boolean
C0040615 (UMLS CUI [1])
C0040615 (UMLS CUI [2,1])
C0392747 (UMLS CUI [2,2])
C1517001 (UMLS CUI [2,3])
C1457887 (UMLS CUI [3,1])
C0205322 (UMLS CUI [3,2])
C0879626 (UMLS CUI [4,1])
C0549178 (UMLS CUI [4,2])
Paliperidone ER | Atypical antipsychotic Quantity
Item
treating physician has determined, before the patient enters the study, that starting paliperidone extended release (er) or another of at least two possible atypical antipsychotics (aaps) is an appropriate treatment for the patient
boolean
C0753678 (UMLS CUI [1,1])
C1707968 (UMLS CUI [1,2])
C1276996 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
Outpatient Probably
Item
likely to be managed as outpatient
boolean
C0029921 (UMLS CUI [1,1])
C0750492 (UMLS CUI [1,2])
Informed Consent Pharmacogenomic Analysis
Item
must have signed the informed consent form for dna pharmacogenomic
boolean
C0021430 (UMLS CUI [1,1])
C4084975 (UMLS CUI [1,2])
Mental Retardation | Dementia | Bipolar Disorder | Schizoaffective Disorder | Schizophreniform Disorders | Mental disorders | Nervous system disorder Worsening
Item
have mental retardation, dementia, bipolar, schizoaffective disorder, schizophreniform disease, other diagnostic and statistical manual of mental disorders, 4th edition (dsm-iv) psychiatric disorders or deteriorating neurological illnesses as determined by clinical evaluation
boolean
C0025362 (UMLS CUI [1])
C0497327 (UMLS CUI [2])
C0005586 (UMLS CUI [3])
C0036337 (UMLS CUI [4])
C0036358 (UMLS CUI [5])
C0004936 (UMLS CUI [6])
C0027765 (UMLS CUI [7,1])
C0332271 (UMLS CUI [7,2])
Treatment-resistant schizophrenia | Atypical antipsychotic Quantity failed | Clozapine | Hospitalization Quantity
Item
established treatment-resistant schizophrenia, defined as those who have had treatment failures with adequate trials of two second generation atypicals, previous treatment with clozapine, or 4 or more hospitalizations in the last 12 months
boolean
C3544321 (UMLS CUI [1])
C1276996 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
C0231175 (UMLS CUI [2,3])
C0009079 (UMLS CUI [3])
C0019993 (UMLS CUI [4,1])
C1265611 (UMLS CUI [4,2])
Violence | At risk for suicide Immediate | At risk Self-harming behaviors | At risk of harming others | At risk Causing Damage Property
Item
history of recent violence or at immediate risk of suicide, or harming self or others, or of causing damage to property, in the judgment of the investigator
boolean
C0042693 (UMLS CUI [1])
C0563664 (UMLS CUI [2,1])
C0205253 (UMLS CUI [2,2])
C1444641 (UMLS CUI [3,1])
C3280486 (UMLS CUI [3,2])
C1271966 (UMLS CUI [4])
C1444641 (UMLS CUI [5,1])
C0678227 (UMLS CUI [5,2])
C1883709 (UMLS CUI [5,3])
C0871161 (UMLS CUI [5,4])
Lacking Able to swallow Oral medication
Item
patients who are unable to swallow the medication whole
boolean
C0332268 (UMLS CUI [1,1])
C2712086 (UMLS CUI [1,2])
C0175795 (UMLS CUI [1,3])
Medical History At risk Torsades de Pointes | Medical History At risk Sudden death | Circumstances At risk Torsades de Pointes | Circumstances At risk Sudden death | Prolonged QTc interval Due to Drug use | Bradycardia | Hypokalemia | Hypomagnesemia | Congenital long QT syndrome
Item
history or circumstances that may increase the risk of occurrence of torsade de pointes and/or sudden death in association with the use of drugs that prolong the qtc interval, including bradycardia, hypokalemia or hypomagnesemia, concomitant use of drugs that prolong the qtc interval, or presence of congenital long qt syndrome
boolean
C0262926 (UMLS CUI [1,1])
C1444641 (UMLS CUI [1,2])
C0040479 (UMLS CUI [1,3])
C0262926 (UMLS CUI [2,1])
C1444641 (UMLS CUI [2,2])
C0011071 (UMLS CUI [2,3])
C0680082 (UMLS CUI [3,1])
C1444641 (UMLS CUI [3,2])
C0040479 (UMLS CUI [3,3])
C0680082 (UMLS CUI [4,1])
C1444641 (UMLS CUI [4,2])
C0011071 (UMLS CUI [4,3])
C1560305 (UMLS CUI [5,1])
C0678226 (UMLS CUI [5,2])
C0242510 (UMLS CUI [5,3])
C0428977 (UMLS CUI [6])
C0020621 (UMLS CUI [7])
C0151723 (UMLS CUI [8])
C1141890 (UMLS CUI [9])
Pregnancy Urine pregnancy test | Pregnancy, Planned | Breast Feeding
Item
pregnant (as confirmed by urine pregnancy test performed at baseline), planning to become pregnant, or breast-feeding.
boolean
C0032961 (UMLS CUI [1,1])
C0430056 (UMLS CUI [1,2])
C0032992 (UMLS CUI [2])
C0006147 (UMLS CUI [3])