Age
Item
males and females, 18 to 60 year old, inclusive.
boolean
C0001779 (UMLS CUI [1])
Multiple Sclerosis, Acute Relapsing | Demyelination Episode Quantity | Magnetic resonance imaging of brain abnormal
Item
diagnosis of a relapsing form of multiple sclerosis as determined by revised mcdonald criteria or at least one clinical demyelinating episode with abnormal brain mri study based on champs criteria
boolean
C0393664 (UMLS CUI [1])
C0011304 (UMLS CUI [2,1])
C0332189 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
C1319851 (UMLS CUI [3])
Kurtzke multiple sclerosis rating scale
Item
expanded disability status scale (edss) score less than 6 at entry.
boolean
C0451246 (UMLS CUI [1])
Informed Consent
Item
understand and sign written informed consent prior to any testing under this protocol, including screening tests and evaluations that are not considered part of the subject's routine care.
boolean
C0021430 (UMLS CUI [1])
Adrenal Cortex Hormones | Biological Response Modifiers
Item
treatment with corticosteroids within one month prior to the study. treatment with immunomodulatory drugs within last 3 months prior to the study.
boolean
C0001617 (UMLS CUI [1])
C0005525 (UMLS CUI [2])
Pharmaceutical Preparations Interferon-beta Based
Item
no history of treatment with interferon-beta(ifn-beta) based drugs to exclude the possibility of ifn-beta neutralizing antibodies
boolean
C0013227 (UMLS CUI [1,1])
C0015980 (UMLS CUI [1,2])
C1705938 (UMLS CUI [1,3])
Pregnancy | Pregnancy, Planned | Breast Feeding
Item
any patient who is pregnant, intend to become pregnant, or breastfeeding at any time of the study.
boolean
C0032961 (UMLS CUI [1])
C0032992 (UMLS CUI [2])
C0006147 (UMLS CUI [3])
Heart Diseases | Gastrointestinal Diseases | Liver diseases | Lung diseases | Kidney Diseases | Immunologic Deficiency Syndromes | Medical condition Excludes Beta interferon therapy
Item
history of any significant cardiac, gastrointestinal, hepatic, pulmonary, or renal disease; immune deficiency; or other medical conditions that would preclude ifn-beta therapy.
boolean
C0018799 (UMLS CUI [1])
C0017178 (UMLS CUI [2])
C0023895 (UMLS CUI [3])
C0024115 (UMLS CUI [4])
C0022658 (UMLS CUI [5])
C0021051 (UMLS CUI [6])
C3843040 (UMLS CUI [7,1])
C0332196 (UMLS CUI [7,2])
C0854622 (UMLS CUI [7,3])
Multiple Sclerosis, Primary Progressive | Secondary Progressive Multiple Sclerosis Relapse Lacking
Item
primary progressive multiple sclerosis patients or patients with secondary progressive multiple sclerosis with lack of recent clinical relapses for more than 2 years
boolean
C0751964 (UMLS CUI [1])
C0751965 (UMLS CUI [2,1])
C0035020 (UMLS CUI [2,2])
C0332268 (UMLS CUI [2,3])