Major Depressive Disorder
Item
major depression diagnosed by psychiatrist
boolean
C1269683 (UMLS CUI [1])
Single major depressive episode | Recurrent major depressive episodes
Item
dsm iv tr: 296.2x single depressive episode or 296.3x recurrent depressive episode
boolean
C0024517 (UMLS CUI [1])
C0154409 (UMLS CUI [2])
Hamilton rating scale for depression
Item
hamd-17 score ≥ 22
boolean
C0451203 (UMLS CUI [1])
Depression, psychotic | Bipolar Disorder | Obsessive-Compulsive Disorder | Anxiety Disorders | Personality Disorders | Substance Use Disorders | Schizoaffective Disorder | Schizophrenia
Item
psychotic depression, bipolar disorder, obsessive compulsive disorder, anxiety disorder, personality disorder, drug or alcohol abuse, schizoaffective disorders, schizophrenia
boolean
C0743072 (UMLS CUI [1])
C0005586 (UMLS CUI [2])
C0028768 (UMLS CUI [3])
C0003469 (UMLS CUI [4])
C0031212 (UMLS CUI [5])
C0038586 (UMLS CUI [6])
C0036337 (UMLS CUI [7])
C0036341 (UMLS CUI [8])
Axis I diagnosis | Exception Depressive disorder
Item
all dsm iv tr axis-i disorders except depression
boolean
C0270287 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0011581 (UMLS CUI [2,2])
Axis II diagnosis
Item
all dsm iv tr axis-ii disorders without exception
boolean
C0270288 (UMLS CUI [1])
Antidepressive Agents Quantity Unsuccessful
Item
unsuccessful treatment with more than 2 antidepressant medications
boolean
C0003289 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C1272705 (UMLS CUI [1,3])
Psychotropic Drugs | Mood Stabilizers
Item
concomitant use of psychotropic drugs, including mood stabilizers
boolean
C0033978 (UMLS CUI [1])
C4020582 (UMLS CUI [2])
Suicidal behavior Risk Immediate
Item
immediate risk of suicidal behaviour
boolean
C1760428 (UMLS CUI [1,1])
C0035647 (UMLS CUI [1,2])
C0205253 (UMLS CUI [1,3])
Pregnancy | Breast Feeding | Pregnancy, Planned | Gender Postmenopausal state Absent | Gender Female Sterilization Absent | Gender Contraceptive methods Lacking
Item
women who are pregnant, breast feeding or planning to become pregnant during the course of study, women who are not post-menopausal, surgically sterilized or using an effective method of contraception
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0032992 (UMLS CUI [3])
C0079399 (UMLS CUI [4,1])
C0232970 (UMLS CUI [4,2])
C0332197 (UMLS CUI [4,3])
C0079399 (UMLS CUI [5,1])
C0015787 (UMLS CUI [5,2])
C0332197 (UMLS CUI [5,3])
C0079399 (UMLS CUI [6,1])
C0700589 (UMLS CUI [6,2])
C0332268 (UMLS CUI [6,3])
Cardiovascular Diseases | Angina Pectoris | Myocardial Infarction | Cerebrovascular accident | Congestive heart failure | Uncontrolled hypertension | Peripheral arterial insufficiency | Claudication Symptomatic | Peripheral arterial embolism
Item
any history of cardiovascular disease (e.g. angina, heart attack, stroke, congestive heart failure), uncontrolled high blood pressure, documented peripheral arterial insufficiency and symptomatic, clinically significant claudication, or a history of peripheral arterial embolism
boolean
C0007222 (UMLS CUI [1])
C0002962 (UMLS CUI [2])
C0027051 (UMLS CUI [3])
C0038454 (UMLS CUI [4])
C0018802 (UMLS CUI [5])
C1868885 (UMLS CUI [6])
C0281943 (UMLS CUI [7])
C1456822 (UMLS CUI [8,1])
C0231220 (UMLS CUI [8,2])
C0564750 (UMLS CUI [9])
Coronary heart disease | Heart Diseases
Item
history of coronary heart disease (chd) or any other heart disease
boolean
C0010068 (UMLS CUI [1])
C0018799 (UMLS CUI [2])
Ulceration Upper Gastrointestinal Tract | Ulceration Lower Gastrointestinal Tract | UPPER GASTROINTESTINAL PERFORATION | Gastrointestinal perforation Lower Tract | Obstruction Upper Gastrointestinal Tract | Obstruction Lower Gastrointestinal Tract
Item
history of upper or lower gastrointestinal (gi) ulceration, perforation and/or obstruction
boolean
C3887532 (UMLS CUI [1,1])
C3203348 (UMLS CUI [1,2])
C3887532 (UMLS CUI [2,1])
C0226875 (UMLS CUI [2,2])
C0749862 (UMLS CUI [3])
C0151664 (UMLS CUI [4,1])
C0226875 (UMLS CUI [4,2])
C0028778 (UMLS CUI [5,1])
C3203348 (UMLS CUI [5,2])
C0028778 (UMLS CUI [6,1])
C0226875 (UMLS CUI [6,2])
Upper gastrointestinal hemorrhage | Lower gastrointestinal hemorrhage
Item
history of upper or lower gi bleeding within the previous year
boolean
C0041909 (UMLS CUI [1])
C0024050 (UMLS CUI [2])
Inflammatory Bowel Diseases
Item
history of inflammatory bowel disease
boolean
C0021390 (UMLS CUI [1])
Clinical Trial Eligibility Criteria Study Protocol
Item
other protocol-defined inclusion/exclusion criteria may apply
boolean
C1516637 (UMLS CUI [1,1])
C2348563 (UMLS CUI [1,2])