Age
Item
women aged > 60 years and men > 55 years
boolean
C0001779 (UMLS CUI [1])
Cardiovascular risk factor Additional Quantity
Item
at least one additional cv risk factor including:
boolean
C0850624 (UMLS CUI [1,1])
C1524062 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
Waist-Hip Ratio | Gender
Item
waist/hip ratio ≥ 0.90 in men and ≥ 0.85 in women;
boolean
C0205682 (UMLS CUI [1])
C0079399 (UMLS CUI [2])
Tobacco use Regular Duration
Item
history of current or recent smoking (regular tobacco use within 5 years)
boolean
C0543414 (UMLS CUI [1,1])
C0205272 (UMLS CUI [1,2])
C0449238 (UMLS CUI [1,3])
Decreased HDL cholesterol
Item
low hdl cholesterol
boolean
C0151691 (UMLS CUI [1])
Dysglycemia
Item
dysglycemia
boolean
C1960636 (UMLS CUI [1])
Renal dysfunction
Item
renal dysfunction
boolean
C3279454 (UMLS CUI [1])
FH: premature coronary heart disease First Degree Relative
Item
family history of premature chd in first degree relatives
boolean
C1277208 (UMLS CUI [1,1])
C1517194 (UMLS CUI [1,2])
Atherothrombosis Cardiovascular Disease
Item
documented clinically manifest atherothrombotic cvd
boolean
C1963943 (UMLS CUI [1,1])
C0007222 (UMLS CUI [1,2])
Indication Statin | Indication Angiotensin II receptor antagonist | Indication Angiotensin-Converting Enzyme Inhibitors | Indication Thiazide Diuretics | Medical contraindication Statin | Medical contraindication Angiotensin II receptor antagonist | Medical contraindication Angiotensin-Converting Enzyme Inhibitors | Medical contraindication Thiazide Diuretics
Item
clear indication or contraindication for statin and/or arb or ace inhibitor and/or thiazide diuretic therapy
boolean
C3146298 (UMLS CUI [1,1])
C0360714 (UMLS CUI [1,2])
C3146298 (UMLS CUI [2,1])
C0521942 (UMLS CUI [2,2])
C3146298 (UMLS CUI [3,1])
C0003015 (UMLS CUI [3,2])
C3146298 (UMLS CUI [4,1])
C0012802 (UMLS CUI [4,2])
C1301624 (UMLS CUI [5,1])
C0360714 (UMLS CUI [5,2])
C1301624 (UMLS CUI [6,1])
C0521942 (UMLS CUI [6,2])
C1301624 (UMLS CUI [7,1])
C0003015 (UMLS CUI [7,2])
C1301624 (UMLS CUI [8,1])
C0012802 (UMLS CUI [8,2])
Hypotension symptomatic
Item
symptomatic hypotension
boolean
C0863113 (UMLS CUI [1])
Chronic liver disease
Item
chronic liver disease
boolean
C0341439 (UMLS CUI [1])
Myositis
Item
inflammatory muscle disease
boolean
C0027121 (UMLS CUI [1])
Renal Insufficiency
Item
renal impairment
boolean
C1565489 (UMLS CUI [1])
Cyclosporine | Condition Resulting in Organ Transplantation | Condition Requirement Cyclosporine
Item
concurrent treatment with cyclosporine or a condition likely to result in organ transplantation and the need for cyclosporine
boolean
C0010592 (UMLS CUI [1])
C0348080 (UMLS CUI [2,1])
C0332294 (UMLS CUI [2,2])
C0029216 (UMLS CUI [2,3])
C0348080 (UMLS CUI [3,1])
C1514873 (UMLS CUI [3,2])
C0010592 (UMLS CUI [3,3])
Statin | Fibrates | Angiotensin II receptor antagonist | Angiotensin-Converting Enzyme Inhibitors | Thiazide Diuretics
Item
concurrent treatment with a statin, fibrate, angiotensin receptor blocker, ace inhibitor, or a thiazide diuretic
boolean
C0360714 (UMLS CUI [1])
C1449704 (UMLS CUI [2])
C0521942 (UMLS CUI [3])
C0003015 (UMLS CUI [4])
C0012802 (UMLS CUI [5])
Illness Serious Interferes with Study Subject Participation Status | Illness Serious Interferes with Clinical Trial Completion
Item
other serious medical illness likely to interfere with study participation or with the ability to complete the trial
boolean
C0221423 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C0521102 (UMLS CUI [1,3])
C2348568 (UMLS CUI [1,4])
C0221423 (UMLS CUI [2,1])
C0205404 (UMLS CUI [2,2])
C0521102 (UMLS CUI [2,3])
C0008976 (UMLS CUI [2,4])
C0205197 (UMLS CUI [2,5])
Mental disorders | Senility | Dementia | Substance Use Disorders | Informed Consent Ability Limited | Protocol Compliance Limited
Item
significant psychiatric illness, senility, dementia, alcohol or substance abuse, which could impair the ability to provide informed consent and to adhere to the trial procedures
boolean
C0004936 (UMLS CUI [1])
C0231337 (UMLS CUI [2])
C0497327 (UMLS CUI [3])
C0038586 (UMLS CUI [4])
C0021430 (UMLS CUI [5,1])
C0085732 (UMLS CUI [5,2])
C0439801 (UMLS CUI [5,3])
C0525058 (UMLS CUI [6,1])
C0439801 (UMLS CUI [6,2])
Pharmacologic Substance Investigational
Item
concurrent use of an experimental pharmacological agent
boolean
C1254351 (UMLS CUI [1,1])
C1517586 (UMLS CUI [1,2])