Criteria Fulfill
Item
patient must either:
boolean
C0243161 (UMLS CUI [1,1])
C1550543 (UMLS CUI [1,2])
Pulmonary arterial hypertension
Item
meet the pah diagnostic criteria at screening (based on a documented history of diagnosis as outlined in the american college of chest physicians [accp] 2004 evidence-based clinical practices guidelines)15; or
boolean
C2973725 (UMLS CUI [1])
Pulmonary arterial pressure elevated | Pulmonary arterial hypertension Suspected | Clinical referral Catheterization of right heart
Item
have elevated pulmonary pressure with a suspected pah diagnosis based on a clinical referral at screening for a rhc.
boolean
C3670875 (UMLS CUI [1])
C2973725 (UMLS CUI [2,1])
C0332147 (UMLS CUI [2,2])
C1545725 (UMLS CUI [3,1])
C0189896 (UMLS CUI [3,2])
Pulmonary arterial hypertension | Pulmonary artery mean pressure
Item
patient must have pah as defined by a mean pulmonary artery pressure (pap) > 25 mmhg.
boolean
C2973725 (UMLS CUI [1])
C0428645 (UMLS CUI [2])
Symptoms Pulmonary Hypertension | WHO Pulmonary arterial hypertension Class Functional
Item
patient must have symptoms of pulmonary hypertension (ph) according to the world health organization (who) functional classification of pulmonary hypertension class ii through iv.
boolean
C1457887 (UMLS CUI [1,1])
C0020542 (UMLS CUI [1,2])
C0043237 (UMLS CUI [2,1])
C2973725 (UMLS CUI [2,2])
C0456387 (UMLS CUI [2,3])
C0205245 (UMLS CUI [2,4])
Venous access Swan-Ganz Catheterization | Access Arterial Swan-Ganz Catheterization | Arterial Line
Item
patient must consent to, be able to tolerate, and have adequate venous and arterial access for swan-ganz catheterization (sgc) and an arterial line.
boolean
C3164222 (UMLS CUI [1,1])
C0007438 (UMLS CUI [1,2])
C0444454 (UMLS CUI [2,1])
C0221464 (UMLS CUI [2,2])
C0007438 (UMLS CUI [2,3])
C0003835 (UMLS CUI [3])
Shunt right-left intracardiac Doppler Echocardiography
Item
clinically significant right-to-left intracardiac shunts based on doppler echocardiography with bubble study.
boolean
C0489644 (UMLS CUI [1,1])
C0013520 (UMLS CUI [1,2])
Pulmonary Veno-Occlusive Disease | Aortic Valve Stenosis | Mitral Valve Stenosis
Item
history of pulmonary veno-occlusive disease or clinically significant aortic or mitral stenosis.
boolean
C0034091 (UMLS CUI [1])
C0003507 (UMLS CUI [2])
C0026269 (UMLS CUI [3])
Sustained ventricular tachycardia | Ventricular Fibrillation | Cardiac Arrest | Atrial Fibrillation
Item
history of sustained ventricular tachycardia (vt-s) or ventricular fibrillation (vf) and cardiac arrest, or presence of atrial fibrillation.
boolean
C0750197 (UMLS CUI [1])
C0042510 (UMLS CUI [2])
C0018790 (UMLS CUI [3])
C0004238 (UMLS CUI [4])
Heart Disease
Item
active cardiac disease meeting the following criteria:
boolean
C0018799 (UMLS CUI [1])
Increased pulmonary arterial wedge pressure
Item
patient with elevated pulmonary capillary wedge pressures (pcwps) > 25 mmhg.
boolean
C0520850 (UMLS CUI [1])
Myocardial Infarction | Percutaneous Coronary Intervention
Item
patient with a history of myocardial infarction or coronary intervention within the last 60 days.
boolean
C0027051 (UMLS CUI [1])
C1532338 (UMLS CUI [2])
Artificial cardiac pacemaker | Cardiac defibrillator | Biventricular pacemaker insertion
Item
patient with a history of pacemaker, cardiac defibrillator, or biventricular pacemaker insertion within 4 weeks of baseline.
boolean
C0030163 (UMLS CUI [1])
C1391956 (UMLS CUI [2])
C3805138 (UMLS CUI [3])
Nitrates therapy Withdrawal Unsuccessful
Item
patient who cannot be withdrawn from nitrate therapy.
boolean
C0028125 (UMLS CUI [1,1])
C0039798 (UMLS CUI [1,2])
C2349954 (UMLS CUI [1,3])
C1272705 (UMLS CUI [1,4])