Non-Small Cell Lung Carcinoma Advanced Local Unresectable TNM clinical staging
Item
histologically or cytologically confirmed, unresectable locally advanced (stage iiia/iiib) nsclc
boolean
C0007131 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C0205276 (UMLS CUI [1,3])
C1519810 (UMLS CUI [1,4])
C3258246 (UMLS CUI [1,5])
Non-Small Cell Lung Carcinoma Therapeutic procedure Absent
Item
no previous therapy for nsclc is allowed
boolean
C0007131 (UMLS CUI [1,1])
C0087111 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
Age
Item
age >18 years
boolean
C0001779 (UMLS CUI [1])
Measurable Disease 2-Dimensional
Item
bidimensionally measurable disease
boolean
C1513041 (UMLS CUI [1,1])
C1705052 (UMLS CUI [1,2])
WHO performance status scale
Item
performance status (who) 0-2
boolean
C1298650 (UMLS CUI [1])
Pleural effusion Absent
Item
absence of pleural effusion
boolean
C0032227 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Liver function | Serum total bilirubin measurement | Aspartate aminotransferase measurement | Alanine aminotransferase measurement | Secondary malignant neoplasm of liver Absent | Secondary malignant neoplasm of liver Present | Renal function | Creatinine measurement, serum | Bone Marrow function | Neutrophil count | Platelet Count measurement
Item
adequate liver (serum bilirubin < 1.5 times the upper normal limit (unl); ast and alt < 2.5 times the unl in the absence of demonstrable liver metastases, or < 5 times the unl in the presence of liver metastases); adequate renal function (serum creatinine < 1.5 times the unl); and bone marrow (neutrophils ≥ 1.5x 109 /l, and platelets ≥ 100x 109 /l) function
boolean
C0232741 (UMLS CUI [1])
C1278039 (UMLS CUI [2])
C0201899 (UMLS CUI [3])
C0201836 (UMLS CUI [4])
C0494165 (UMLS CUI [5,1])
C0332197 (UMLS CUI [5,2])
C0494165 (UMLS CUI [6,1])
C0150312 (UMLS CUI [6,2])
C0232804 (UMLS CUI [7])
C0201976 (UMLS CUI [8])
C0005953 (UMLS CUI [9,1])
C0031843 (UMLS CUI [9,2])
C0200633 (UMLS CUI [10])
C0032181 (UMLS CUI [11])
Life Expectancy
Item
life expectancy of more than 3 months
boolean
C0023671 (UMLS CUI [1])
Informed Consent
Item
written informed consent
boolean
C0021430 (UMLS CUI [1])
Communicable Disease
Item
active infection
boolean
C0009450 (UMLS CUI [1])
Heart Disease | Angina, Unstable | Congestive heart failure | Myocardial Infarction | Ventricular arrhythmia
Item
history of significant cardiac disease (unstable angina, congestive heart failure, myocardial infarction within the previous 6 months, ventricular arrhythmias)
boolean
C0018799 (UMLS CUI [1])
C0002965 (UMLS CUI [2])
C0018802 (UMLS CUI [3])
C0027051 (UMLS CUI [4])
C0085612 (UMLS CUI [5])
Malnutrition | Weight decreased Percentage | Body Weight
Item
malnutrition (loss of ≥ 20% of the original body weight)
boolean
C0162429 (UMLS CUI [1])
C1262477 (UMLS CUI [2,1])
C0439165 (UMLS CUI [2,2])
C0005910 (UMLS CUI [3])
performance status
Item
performance status: 3-4
boolean
C1518965 (UMLS CUI [1])
Sensory neuropathy CTCAE Grades | Motor neuropathy CTCAE Grades
Item
sensor or motor neuropathy > grade i
boolean
C0151313 (UMLS CUI [1,1])
C1516728 (UMLS CUI [1,2])
C0235025 (UMLS CUI [2,1])
C1516728 (UMLS CUI [2,2])
Second Primary Cancers | Skin carcinoma
Item
second primary malignancy, except for non-melanoma skin cancer
boolean
C0751623 (UMLS CUI [1])
C0699893 (UMLS CUI [2])
Mental disorder Protocol Compliance Excluded | Social situation Protocol Compliance Excluded
Item
psychiatric illness or social situation that would preclude study compliance
boolean
C0004936 (UMLS CUI [1,1])
C0525058 (UMLS CUI [1,2])
C2828389 (UMLS CUI [1,3])
C0748872 (UMLS CUI [2,1])
C0525058 (UMLS CUI [2,2])
C2828389 (UMLS CUI [2,3])
Pregnancy | Breast Feeding
Item
pregnant or lactating women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])