Non-small cell lung cancer
Item
histologically or cytologically confirmed non-small cell lung cancer (nsclc).
boolean
C0007131 (UMLS CUI [1])
Age
Item
age at least 18 years. no upper age limit.
boolean
C0001779 (UMLS CUI [1])
Tumor Stage
Item
disease stage iiib or iv.
boolean
C1300072 (UMLS CUI [1])
Performance Status
Item
performance status (who) 0-2
boolean
C1518965 (UMLS CUI [1])
Curative Intention
Item
treatment with curative intent is not possible
boolean
C1276305 (UMLS CUI [1])
Prior chemotherapy
Item
no prior chemotherapy for the present disease
boolean
C1514457 (UMLS CUI [1])
Palliative Chemotherapy
Item
planned treatment is palliative chemotherapy
boolean
C4272534 (UMLS CUI [1])
WBC, Platelets
Item
wbc count at least 3.0, platelet count at least 100
boolean
C0023508 (UMLS CUI [1])
C0005821 (UMLS CUI [2])
Bilirubin, ASAT, ALAT
Item
bilirubin < 1.5 * upper reference limit (url), asat and alat < 3 * url (<5 in case of liver metastases)
boolean
C1278039 (UMLS CUI [1])
C0201899 (UMLS CUI [2])
C0201836 (UMLS CUI [3])
Creatinine Clearance
Item
calculated creatinine clearance at least 40 mg/ml
boolean
C0373595 (UMLS CUI [1])
Informed Consent
Item
informed oral and written consent
boolean
C0021430 (UMLS CUI [1])
NSAID Use
Item
regular use of nsaid (except asa at a dose of 50-100 mg daily)
boolean
C0003211 (UMLS CUI [1,1])
C1524063 (UMLS CUI [1,2])
Duodenal ulcer, gastrointestinal bleeding or inflammatory bowel disease
Item
active duodenal ulcer, ongoing gastrointestinal bleeding or inflammatory bowel disease
boolean
C0013295 (UMLS CUI [1])
C0017181 (UMLS CUI [2])
C0021390 (UMLS CUI [3])
Heart failure or Liver disease
Item
serious heart failure or serious liver disease
boolean
C0018801 (UMLS CUI [1])
C0023895 (UMLS CUI [2])
Hypersensitivity to sulfonamides
Item
hypersensitivity to sulfonamides
boolean
C0020517 (UMLS CUI [1,1])
C0038760 (UMLS CUI [1,2])
Pregnancy
Item
pregnancy
boolean
C0032961 (UMLS CUI [1])
Lactation
Item
lactation
boolean
C0006147 (UMLS CUI [1])