Criteria for neuromyelitis optica
Item
criteria for neuromyelitis optical
boolean
C0027873 (UMLS CUI [1,1])
C0243161 (UMLS CUI [1,2])
Optic neuritis
Item
optic neuritis
boolean
C0029134 (UMLS CUI [1])
Acute myelitis
Item
acute myelitis
boolean
C0014059 (UMLS CUI [1])
Supportive criteria
Item
at least two of three supportive criteria:
boolean
C1521721 (UMLS CUI [1,1])
C0243161 (UMLS CUI [1,2])
Spinal MRI lesion
Item
contiguous spinal cord mri lesion extending over >= 3 vertebral segments
boolean
C0024485 (UMLS CUI [1,1])
C0221198 (UMLS CUI [1,2])
C0521329 (UMLS CUI [1,3])
Brain MRI for multiple sclerosis
Item
brain mri not meeting diagnostic criteria for multiple sclerosis
boolean
C0412675 (UMLS CUI [1,1])
C0026769 (UMLS CUI [1,2])
NMO-IgG Status
Item
nmo-igg seropositive status
boolean
C0027873 (UMLS CUI [1,1])
C0020852 (UMLS CUI [1,2])
Multiple Sclerosis Criteria
Item
criteria for multiple sclerosis:
boolean
C0026769 (UMLS CUI [1,1])
C0243161 (UMLS CUI [1,2])
Attacks or lesion
Item
two or more attacks; objective clinical evidence of two or more lesions, or
boolean
C0014544 (UMLS CUI [1])
C0026769 (UMLS CUI [2,1])
C0221198 (UMLS CUI [2,2])
MRI for MS, CSF
Item
two or more attacks; objective clinical evidence of one lesion, dissemination in space, demonstrated by: mri or two or more mri-detected lesions consistent with ms plus positive csf or wait further clinical attack implicating a different site, or
boolean
C0026769 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
C0007806 (UMLS CUI [2])
Lesion: Dissemination in time
Item
one attack; objective clinical evidence of two or more lesions, dissemination in time, demonstrated by: mri or second clinical attack, or
boolean
C0205221 (UMLS CUI [1,1])
C0040223 (UMLS CUI [1,2])
C0221198 (UMLS CUI [1,3])
Lesion: Dissemination in space
Item
one attack; objective clinical evidence of one lesion (monosymptomatic presentation; clinically isolated syndrome), dissemination in space, demonstrated by: mri or two or more mri-detected lesions consistent with ms plus positive csf and dissemination in time, demonstrated by: mri or second clinical attack, or
boolean
C0205221 (UMLS CUI [1,1])
C1883067 (UMLS CUI [1,2])
C0221198 (UMLS CUI [1,3])
Disease progression
Item
insidious neurological progression suggestive of ms, one year of disease progression (retrospectively or prospectively determined) and two of the following:
boolean
C0242656 (UMLS CUI [1])
Brain MRI
Item
1. positive brain mri (nine t2 lesions or four or more t2 lesions with positive vep)
boolean
C0412675 (UMLS CUI [1])
Spinal Cord MRI
Item
2. positive spinal cord mri (two focal t2 lesions)
boolean
C2454646 (UMLS CUI [1])
CSF
Item
3. positive csf
boolean
C0007806 (UMLS CUI [1])
Age
Item
> 65 yrs old
boolean
C0001779 (UMLS CUI [1])
Organ function
Item
heavy damage of heart, lung, liver, renal function
boolean
C0678852 (UMLS CUI [1])
Late neuromyelitis optica or EDSS
Item
late neuromyelitis optical or edss > 6.0
boolean
C0027873 (UMLS CUI [1,1])
C0205087 (UMLS CUI [1,2])
C0451246 (UMLS CUI [2])
Hypertension and diabetes mellitus
Item
serious hypertension and diabetes
boolean
C0020538 (UMLS CUI [1])
C0011849 (UMLS CUI [2])
Mental disorder or depression
Item
serious mental disorders and depression
boolean
C0004936 (UMLS CUI [1])
C0011581 (UMLS CUI [2])
Hypersensitivity to atorvastatin, β-interferon, epo, immunoglobulin
Item
allergic to drug: atorvastatin, β-interferon, epo, immunoglobulin
boolean
C0020517 (UMLS CUI [1,1])
C0286651 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0015980 (UMLS CUI [2,2])
C0020517 (UMLS CUI [3,1])
C0014822 (UMLS CUI [3,2])
C0020517 (UMLS CUI [4,1])
C0021027 (UMLS CUI [4,2])