Philadelphia chromosome positive chronic myelogenous leukemia Chronic phase | Response Suboptimal | imatinib Dosage | Hematologic Response Less Than Complete Hematologic Response | Cytogenetic Response Less Than Cytogenetic Partial Response | Cytogenetic Partial Response | Cytogenetic Response Less Than Molecular Major Response | Cytogenetic Complete Response
Item
chronic phase ph^+ chronic myeloid leukemia (cml) demonstrating only a suboptimal response, defined as a hematologic response that is less than a complete hematologic response after at least 3 months of monotherapy with imatinib, 400 mg; a cytogenic response (cgr) that is less than a partial cgr (pcgr) after at least 6 months of monotherapy with imatinib, 400 mg; a pcgr after at least 12 months of monotherapy with imatinib, 400 mg; or less than a major molecular response with a complete cgr after at least 18 months of monotherapy with imatinib, 400 mg.
boolean
C0279543 (UMLS CUI [1,1])
C0457343 (UMLS CUI [1,2])
C1704632 (UMLS CUI [2,1])
C2984009 (UMLS CUI [2,2])
C0935989 (UMLS CUI [3,1])
C0178602 (UMLS CUI [3,2])
C4054793 (UMLS CUI [4,1])
C0439092 (UMLS CUI [4,2])
C4050175 (UMLS CUI [4,3])
C4055168 (UMLS CUI [5,1])
C0439092 (UMLS CUI [5,2])
C4055169 (UMLS CUI [5,3])
C4055169 (UMLS CUI [6])
C4055168 (UMLS CUI [7,1])
C0439092 (UMLS CUI [7,2])
C4049637 (UMLS CUI [7,3])
C4050364 (UMLS CUI [8])
Gender Both
Item
either gender
boolean
C0079399 (UMLS CUI [1,1])
C1706086 (UMLS CUI [1,2])
Age
Item
age of 18 years or older
boolean
C0001779 (UMLS CUI [1])
Accelerated phase chronic myologenic leukemia | Leukemia, blastic crisis (CML)
Item
previous diagnosis of accelerated phase or blast crisis cml
boolean
C0919870 (UMLS CUI [1])
C0687162 (UMLS CUI [2])
Cardiovascular Disease Uncontrolled | Cardiovascular Disease Significant
Item
uncontrolled or significant cardiovascular disease
boolean
C0007222 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0007222 (UMLS CUI [2,1])
C0750502 (UMLS CUI [2,2])
Blood Coagulation Disorder | CML Relationship Absent
Item
history of significant bleeding disorder unrelated to cml
boolean
C0005779 (UMLS CUI [1])
C0023473 (UMLS CUI [2,1])
C0439849 (UMLS CUI [2,2])
C0332197 (UMLS CUI [2,3])
Malignant Neoplasms
Item
concurrent malignancies
boolean
C0006826 (UMLS CUI [1])
intolerance to imatinib Dosage
Item
intolerance of imatinib, 400 mg
boolean
C1744706 (UMLS CUI [1,1])
C0935989 (UMLS CUI [1,2])
C0178602 (UMLS CUI [1,3])
imatinib Dosage
Item
prior treatment with imatinib at a dose higher than 400 mg
boolean
C0935989 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
Stem cell transplant CML | HIGH DOSE CHEMOTHEARPY CML
Item
prior stem cell transplantation and/or high-dose chemotherapy for cml
boolean
C1504389 (UMLS CUI [1,1])
C0023473 (UMLS CUI [1,2])
C0149710 (UMLS CUI [2,1])
C0023473 (UMLS CUI [2,2])