Chronic Hepatitis C
Item
patients diagnosed with chronic hepatitis c
boolean
C0524910 (UMLS CUI [1])
Interferon-therapy, viral load, HCV genotype
Item
among interferon-naïve patients, only patients with high viral load and hcv genotype other than 1
boolean
C0279030 (UMLS CUI [1])
C1261478 (UMLS CUI [2])
C1148363 (UMLS CUI [3])
Nonresponder to Interferon-therapy, viral load, HCV genotype
Item
among prior nonresponders or relapsers to interferon monotherapy, (1) patients with high viral load and hcv genotype other than 1; and (2) patients with low viral load of all genotypes (including genotype 1)
boolean
C3844724 (UMLS CUI [1,1])
C0279030 (UMLS CUI [1,2])
C1261478 (UMLS CUI [2])
C1148363 (UMLS CUI [3])
HCV Genotype 1 and viral load
Item
patients infected with hcv genotype 1 with high viral load, regardless of whether treatment-naïve or previous nonresponders/relapsers
boolean
C3532919 (UMLS CUI [1,1])
C1261478 (UMLS CUI [1,2])
Interferon therapy and viral load
Item
interferon-naïve patients with low viral load
boolean
C0279030 (UMLS CUI [1,1])
C1261478 (UMLS CUI [1,2])
ID.6
Item
patients with a history of hypersensitivity to test drugs or other interferon preparations
boolean
Hypersensitivity to biological products
Item
patients with a history of hypersensitivity to biological products, such as vaccines
boolean
C0020517 (UMLS CUI [1,1])
C0005522 (UMLS CUI [1,2])
Shosaikoto
Item
patients being treated with shosaikoto
boolean
C1138004 (UMLS CUI [1])
Autoimmune hepatitis
Item
patients with autoimmune hepatitis
boolean
C0241910 (UMLS CUI [1])
Gynaecological status
Item
pregnant women, women who may be pregnant, and nursing mothers
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C3831118 (UMLS CUI [3])
Hypersensitivity to nucleoside analogs
Item
patients with a history of hypersensitivity to any component of this drug or other nucleoside analogs (aciclovir, ganciclovir, vidarabine, etc.)
boolean
C0020517 (UMLS CUI [1,1])
C1579410 (UMLS CUI [1,2])
Uncontrolled cardiac disease
Item
patients with difficult-to-control cardiac disease (eg, myocardial infarction, cardiac failure, arrhythmia)
boolean
C0018799 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Hemoglobinopathies
Item
patients with hemoglobinopathies (eg, thalassemia, sickle-cell anemia)
boolean
C0019045 (UMLS CUI [1])
Cronic renal failure or Creatinine clearance
Item
patients with chronic renal failure or renal function disorder with creatinine clearance of <=50 ml/min
boolean
C0022661 (UMLS CUI [1])
C0373595 (UMLS CUI [2])
Severe psychiatric condition
Item
patients with or a history of severe psychiatric condition such as severe depression, suicidal ideation or suicide attempt
boolean
C4046029 (UMLS CUI [1])
Liver function
Item
patients with serious hepatic dysfunction
boolean
C0232741 (UMLS CUI [1])
Autoimmune hepatitis
Item
patients with autoimmune hepatitis
boolean
C0241910 (UMLS CUI [1])