Participation Pulmonary arterial hypertension Placebo controlled study | Pulmonary arterial hypertension Placebo controlled study Discontinued | Worsening Clinical Due to Placebo | Worsening Clinical Due to Tadalafil Dosage
Item
must have participated and discontinued in the previous pah placebo controlled study due to clinical worsening on placebo or tadalafil 2.5 mg, 10mg, or 20 mg
boolean
C0679823 (UMLS CUI [1,1])
C2973725 (UMLS CUI [1,2])
C0599724 (UMLS CUI [1,3])
C2973725 (UMLS CUI [2,1])
C0599724 (UMLS CUI [2,2])
C1444662 (UMLS CUI [2,3])
C0332271 (UMLS CUI [3,1])
C0205210 (UMLS CUI [3,2])
C0678226 (UMLS CUI [3,3])
C1696465 (UMLS CUI [3,4])
C0332271 (UMLS CUI [4,1])
C0205210 (UMLS CUI [4,2])
C0678226 (UMLS CUI [4,3])
C1176316 (UMLS CUI [4,4])
C0178602 (UMLS CUI [4,5])
Pulmonary arterial hypertension Clinical Trial Complete | Worsening Clinical Absent | Worsening Clinical Due to Placebo | Worsening Clinical Due to Tadalafil Dosage
Item
must have completed week 16 of the previous pah study and had either no clinical worsening or became clinically worse at the week 16 visit on placebo or tadalafil 2.5 mg, 10mg, or 20 mg
boolean
C2973725 (UMLS CUI [1,1])
C0008976 (UMLS CUI [1,2])
C0205197 (UMLS CUI [1,3])
C0332271 (UMLS CUI [2,1])
C0205210 (UMLS CUI [2,2])
C0332197 (UMLS CUI [2,3])
C0332271 (UMLS CUI [3,1])
C0205210 (UMLS CUI [3,2])
C0678226 (UMLS CUI [3,3])
C1696465 (UMLS CUI [3,4])
C0332271 (UMLS CUI [4,1])
C0205210 (UMLS CUI [4,2])
C0678226 (UMLS CUI [4,3])
C1176316 (UMLS CUI [4,4])
C0178602 (UMLS CUI [4,5])
Gender Urine pregnancy test negative | Gender Contraceptive methods Type Quantity
Item
females who have a negative urine pregnancy test and are willing to use 2 types of birth control
boolean
C0079399 (UMLS CUI [1,1])
C0430057 (UMLS CUI [1,2])
C0079399 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
C0332307 (UMLS CUI [2,3])
C1265611 (UMLS CUI [2,4])
Age
Item
be 12 years or older (country specific regulations apply) with parental approval
boolean
C0001779 (UMLS CUI [1])
Participation Placebo controlled study | Worsening Clinical Due to Tadalafil Dosage
Item
participated in the placebo controlled study and had clinical worsening on 40 mg tadalafil
boolean
C0679823 (UMLS CUI [1,1])
C0599724 (UMLS CUI [1,2])
C0332271 (UMLS CUI [2,1])
C0205210 (UMLS CUI [2,2])
C0678226 (UMLS CUI [2,3])
C1176316 (UMLS CUI [2,4])
C0178602 (UMLS CUI [2,5])
Heart Disease Left sided
Item
have left-sided heart disease
boolean
C0018799 (UMLS CUI [1,1])
C0443246 (UMLS CUI [1,2])
Musculoskeletal Disease Limiting Able to Get Around
Item
have a musculoskeletal disorder that limits being able to get around
boolean
C0026857 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C3831759 (UMLS CUI [1,3])
Nitrates
Item
nitrate use
boolean
C0028125 (UMLS CUI [1])
systemic therapy
Item
certain current systemic treatments
boolean
C1515119 (UMLS CUI [1])