Age
Item
male or female patients 18-65 years of age, inclusive.
boolean
C0001779 (UMLS CUI [1])
Single major depressive episode Duration | Major Depressive Disorder Recurrent Duration
Item
a diagnosis of mdd, single episode or recurrent, according to dsm-iv-tr (296.2/296.3) with a current major depressive episode of less than two year's duration with a minimum duration of at least 4 weeks.
boolean
C0024517 (UMLS CUI [1,1])
C0449238 (UMLS CUI [1,2])
C1269683 (UMLS CUI [2,1])
C2945760 (UMLS CUI [2,2])
C0449238 (UMLS CUI [2,3])
Hamilton rating scale for depression
Item
ham-d score ≥ 22.
boolean
C0451203 (UMLS CUI [1])
Depressed mood Hamilton rating scale for depression
Item
ham-d item 1 (depressed mood) score ≥ 2.
boolean
C0344315 (UMLS CUI [1,1])
C0451203 (UMLS CUI [1,2])
Informed Consent
Item
patients must be able to provide written informed consent to participate before beginning any trial related activities.
boolean
C0021430 (UMLS CUI [1])
Able to speak English Language | Able to read English Language | Comprehension English Language | Protocol Compliance
Item
patients must be able to speak, read and understand english and possess the ability to respond to questions and follow simple instructions.
boolean
C0564215 (UMLS CUI [1,1])
C0376245 (UMLS CUI [1,2])
C0586740 (UMLS CUI [2,1])
C0376245 (UMLS CUI [2,2])
C0233733 (UMLS CUI [3,1])
C0376245 (UMLS CUI [3,2])
C0525058 (UMLS CUI [4])
Axis I diagnosis | Post-Traumatic Stress Disorder | Eating Disorders | Obsessive-Compulsive Disorder | Generalized Anxiety Disorder | Phobia, Social | Simple phobia
Item
a current (or within 6 months prior to the screening visit) axis i disorder of post traumatic stress disorder, eating disorder, obsessive compulsive disorder (generalized anxiety disorder, social phobia or simple phobia will be allowed).
boolean
C0270287 (UMLS CUI [1])
C0038436 (UMLS CUI [2])
C0013473 (UMLS CUI [3])
C0028768 (UMLS CUI [4])
C0270549 (UMLS CUI [5])
C0031572 (UMLS CUI [6])
C0236801 (UMLS CUI [7])
Schizophrenia | Schizoaffective Disorder | Bipolar I disorder | Bipolar II disorder | hypomanic; episode | Manic episode
Item
a history of schizophrenia, schizoaffective disorder or bipolar i or ii disorder (with a history of hypomanic or manic episodes).
boolean
C0036341 (UMLS CUI [1])
C0036337 (UMLS CUI [2])
C0853193 (UMLS CUI [3])
C0236788 (UMLS CUI [4])
C1396834 (UMLS CUI [5])
C0349208 (UMLS CUI [6])
Substance Use Disorders | Substance Dependence
Item
dsm-iv-tr criteria for substance abuse (alcohol or drugs) within 3 months prior to screening visit or substance dependence within 6 months prior to the screening visit.
boolean
C0038586 (UMLS CUI [1])
C0038580 (UMLS CUI [2])
Major Depressive Disorder Catatonic phenomena | Major Depressive Disorder Onset Postpartum | Major Depressive Disorder Seasonal pattern
Item
criteria for any of the following dsm-iv-tr mdd specifiers: [a] with catatonic features; [b] with postpartum onset; [c] with seasonal pattern.
boolean
C1269683 (UMLS CUI [1,1])
C0856959 (UMLS CUI [1,2])
C1269683 (UMLS CUI [2,1])
C0332162 (UMLS CUI [2,2])
C0086839 (UMLS CUI [2,3])
C1269683 (UMLS CUI [3,1])
C0085159 (UMLS CUI [3,2])