synchronous or metachronous colorectal metastases
Item
synchronous or metachronous colorectal metastases
boolean
C0009404 (UMLS CUI [1,1])
C0027627 (UMLS CUI [1,2])
C0439580 (UMLS CUI [1,3])
C1334703 (UMLS CUI [1,4])
resectable liver metastases
Item
technically resectable liver metastases
boolean
C0494165 (UMLS CUI [1,1])
C1514888 (UMLS CUI [1,2])
metastasis
Item
four or fewer metastases
boolean
C0027627 (UMLS CUI [1])
no tumors in porta hepatis
Item
no tumors in porta hepatis
boolean
C0227498 (UMLS CUI [1,1])
C1269955 (UMLS CUI [1,2])
Partial hepatectomy
Item
resection of no more than 70% of liver needed
boolean
C0193398 (UMLS CUI [1])
medically suitable candidate for major liver resection
Item
medically suitable candidate for major liver resection
boolean
C0193398 (UMLS CUI [1,1])
C0332149 (UMLS CUI [1,2])
FDG-Positron Emission Tomography | Metastatic Neoplasm | Liver
Item
fdg-pet scan without metastatic disease outside the liver
boolean
C3641247 (UMLS CUI [1])
C2939420 (UMLS CUI [2])
C0023884 (UMLS CUI [3])
near-obstructing or obstructing colon lesions
Item
near-obstructing or obstructing colon lesions in patients in whom combined resection is planned (as delay for preoperative chemotherapy would be medially impossible)
boolean
C0235328 (UMLS CUI [1,1])
C0742597 (UMLS CUI [1,2])
prior therapy, folfox, cetuximab
Item
treatment with folfox or cetuximab within 12 months
boolean
C1514463 (UMLS CUI [1])
C0392943 (UMLS CUI [2])
C0995188 (UMLS CUI [3])
prior therapy irinotecan
Item
treatment with irinotecan within 12 months
boolean
C1514463 (UMLS CUI [1,1])
C0123931 (UMLS CUI [1,2])
alt, ast, bilirubin
Item
abnormal liver function (alt or ast > 5x uln, bilirubin > 3x uln)
boolean
C0201836 (UMLS CUI [1,1])
C0201899 (UMLS CUI [1,2])
C1278039 (UMLS CUI [1,3])
bmi
Item
body mass index >/= 35 kg/m² (as the risk for steatohepatitis is increased)
boolean
C1305855 (UMLS CUI [1])
creatinine
Item
renal insufficiency (cr > 2.5mg/dl)
boolean
C0201976 (UMLS CUI [1])
interstitial lung disease
Item
interstitial lung disease (because cetuximab has been rarely associated with development of interstitial lung disease)
boolean
C0206062 (UMLS CUI [1])
ecog
Item
ecog performance score >/= 3
boolean
C1520224 (UMLS CUI [1])
informed consent
Item
patients unable to give informed consent
boolean
C0021430 (UMLS CUI [1])
pregnancy
Item
pregnant patient (as cetuximab is a class c drug)
boolean
C0032961 (UMLS CUI [1])
peripheral neuropathy
Item
peripheral neuropathy >/= grade ii (as oxaliplatin causes neuropathy to worsen)
boolean
C0031117 (UMLS CUI [1])