breast carcinoma histologically confirmed and operable
Item
all patients must have histologically confirmed and newly diagnosed operable breast cancer
boolean
C0678222 (UMLS CUI [1,1])
C0679557 (UMLS CUI [1,2])
C0205188 (UMLS CUI [1,3])
her2 positive
Item
her2 positive (all fish +)
boolean
C1960398 (UMLS CUI [1])
axillary node positive (by pet or cytologically determined node by sonography), tumor size, no prior hormonal, chemotherapy or radiotherapy
Item
axillary node positive (by pet or cytologically determine node by sonography) and/or tumor size > 5 cm -no prior hormonal, chemotherapy or radiotherapy is allowed.
boolean
C0741343 (UMLS CUI [1,1])
C0032743 (UMLS CUI [1,2])
C0010819 (UMLS CUI [1,3])
C2315103 (UMLS CUI [1,4])
C0475440 (UMLS CUI [2])
C1514463 (UMLS CUI [3])
C0877050 (UMLS CUI [4])
C0392920 (UMLS CUI [5])
C1522449 (UMLS CUI [6])
Operation on breast | Core needle biopsy of breast
Item
no breast operation other than biopsy to make diagnosis is allowed.
boolean
C3714726 (UMLS CUI [1])
C0191853 (UMLS CUI [2])
Age | Pregnancy | Gender | ECOG performance status
Item
age: 18-years and older, not pregnant pre-, and postmenopausal women with good performance status (ecog 0-1)
boolean
C0001779 (UMLS CUI [1])
C0032961 (UMLS CUI [2])
C0079399 (UMLS CUI [3])
C1520224 (UMLS CUI [4])
hematopoietic function
Item
adequate hematopoietic function:
boolean
C0541533 (UMLS CUI [1])
absolute granulocyte count
Item
absolute granulocyte count ³1500/mm3,
boolean
C0857490 (UMLS CUI [1])
blood platelet, hemoglobin
Item
platelet ³100,000/mm3, hemoglobin ³ 10 g/mm3
boolean
C0005821 (UMLS CUI [1])
C0019046 (UMLS CUI [2])
creatinine
Item
adequate renal function: serum creatinine £ 1.5 mg/dl
boolean
C0201976 (UMLS CUI [1])
Serum total bilirubin measurement | Aspartate aminotransferase measurement; Alanine aminotransferase measurement | Alkaline phosphatase measurement | Cardiac function
Item
adequate hepatic function: total bilirubin: £ 1.5 mg/dl, ast/alt: £ 2 times normal, alkaline phosphatase: £ 2 times normal-adequate cardiac function:
boolean
C1278039 (UMLS CUI [1])
C0201899 (UMLS CUI [2,1])
C0201836 (UMLS CUI [2,2])
C0201850 (UMLS CUI [3])
C0232164 (UMLS CUI [4])
ekg
Item
1. normal or nonspecific ekg taken within 1 mo of enrollment
boolean
C1623258 (UMLS CUI [1])
lvef by muga or echocardiogram
Item
2. lvef ³ 50% by muga or echocardiogram taken within 1 mo of enrollment
boolean
C0428772 (UMLS CUI [1,1])
C0013516 (UMLS CUI [1,2])
C0521317 (UMLS CUI [1,3])
informed consent, normal mental function
Item
normal mental function to understand and sign the consent
boolean
C0021430 (UMLS CUI [1])
C0004936 (UMLS CUI [2])
Cancer hormonal therapy | Chemotherapy Regimen | Therapeutic radiology procedure | Breast Carcinoma; Prior Therapy
Item
patients who received hormonal, chemotherapy or radiotherapy for breast cancer
boolean
C0877050 (UMLS CUI [1])
C0392920 (UMLS CUI [2])
C1522449 (UMLS CUI [3])
C0678222 (UMLS CUI [4,1])
C1514463 (UMLS CUI [4,2])
Operation on breast; Breast Carcinoma
Item
patients who underwent surgery for breast cancer
boolean
C3714726 (UMLS CUI [1,1])
C0678222 (UMLS CUI [1,2])
Congestive heart failure; Uncompensated | Medical History
Item
patients with a history of uncompensated congestive heart failure
boolean
C0018802 (UMLS CUI [1,1])
C0205433 (UMLS CUI [1,2])
C0262926 (UMLS CUI [2])
Node category finding; Breast Carcinoma
Item
patients with node-negative stage iia (t2n0) breast cancer
boolean
C1272457 (UMLS CUI [1,1])
C0678222 (UMLS CUI [1,2])
Medical History; Malignant Neoplasms | Carcinoma in situ of uterine cervix | Nonmelanoma skin cancer
Item
patients who have history of cancer other than in situ uterine cervix cancer or nonmelanotic skin cancer
boolean
C0262926 (UMLS CUI [1,1])
C0006826 (UMLS CUI [1,2])
C0851140 (UMLS CUI [2])
C3281209 (UMLS CUI [3])