Gastrointestinal Neoplasm Solid | Chemotherapy Quantity
Item
(phase 1) patients with any solid/gi tumor who have had no more than 1 previous chemotherapy for greater than 3 months prior to enrollment
boolean
C0017185 (UMLS CUI [1,1])
C0205208 (UMLS CUI [1,2])
C0392920 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
Colorectal Carcinoma Advanced Local | Colorectal cancer metastatic | Systemic therapy Absent
Item
(phase 2) patients with locally advanced or metastatic colorectal cancer (crc) previously untreated with any systemic therapy.
boolean
C0009402 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C0205276 (UMLS CUI [1,3])
C0948380 (UMLS CUI [2])
C1515119 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
Chemotherapy, Adjuvant | Therapeutic radiology procedure
Item
patients treated with adjuvant chemotherapy (with radiation) will be eligible if last treatment was > 12 months prior to enrollment,
boolean
C0085533 (UMLS CUI [1])
C1522449 (UMLS CUI [2])
Measurable Disease | Hypertensive disease Controlled by Pharmaceutical Preparations
Item
patients must have measurable disease by recist and if any history of hypertension, it must be controlled with medication.
boolean
C1513041 (UMLS CUI [1])
C0020538 (UMLS CUI [2,1])
C0332298 (UMLS CUI [2,2])
C0013227 (UMLS CUI [2,3])
Systemic therapy Colorectal Carcinoma Advanced
Item
prior system therapy for advanced crc (ph 2 portion only)
boolean
C1515119 (UMLS CUI [1,1])
C0009402 (UMLS CUI [1,2])
C0205179 (UMLS CUI [1,3])
Angiogenesis Inhibitors | bevacizumab | Vascular Endothelial Growth Factor Inhibitors
Item
prior treatment with anti-angiogenesis agent such as bevacizumab or vegf inhibitors.
boolean
C0596087 (UMLS CUI [1])
C0796392 (UMLS CUI [2])
C2267120 (UMLS CUI [3])
Therapeutic radiology procedure Bone Marrow Percentage | Therapeutic radiology procedure Whole-Pelvis Percentage
Item
prior irradiation of greater than 25% of bone marrow (whole pelvis = 25%)
boolean
C1522449 (UMLS CUI [1,1])
C0005953 (UMLS CUI [1,2])
C0439165 (UMLS CUI [1,3])
C1522449 (UMLS CUI [2,1])
C3827467 (UMLS CUI [2,2])
C0439165 (UMLS CUI [2,3])
Therapeutic radiology procedure | major surgery | Investigational New Drugs | Palliative course of radiotherapy Metastatic Lesion Non-Target | Minor Surgical Procedures Completed | Interventional procedure Recovered
Item
prior radiation, major surgery, or investigational agent within 4 weeks of study entry except palliative radiotherapy to non-target, metastatic lesions. minor surgeries should be completed > 2 weeks of enrollment and be fully recovered from any procedure.
boolean
C1522449 (UMLS CUI [1])
C0679637 (UMLS CUI [2])
C0013230 (UMLS CUI [3])
C0475092 (UMLS CUI [4,1])
C1513183 (UMLS CUI [4,2])
C1518389 (UMLS CUI [4,3])
C0038904 (UMLS CUI [5,1])
C0205197 (UMLS CUI [5,2])
C0184661 (UMLS CUI [6,1])
C0521108 (UMLS CUI [6,2])