Breast cancer recurrent | Breast Carcinoma TNM clinical staging
Item
histologically proven dx of recurrent or metastatic breast cancer
boolean
C0278493 (UMLS CUI [1])
C0678222 (UMLS CUI [2,1])
C3258246 (UMLS CUI [2,2])
Chemotherapy Regimen Quantity Breast cancer recurrent | Chemotherapy Regimen Quantity Breast Carcinoma TNM clinical staging | Adjuvant Chemotherapy Completed | Recurrent disease | Anthracyclines | taxane
Item
must have received at least 1 but not more than 3 prior chemotherapy regimens for recurrent or metastatic breast cancer. patients who relapse within 12 months of completing adjuvant chemotherapy can only have had up to 2 prior regimens for metastatic disease. patients who relapse within 12 months of completing adjuvant chemotherapy containing an anthracycline and a taxane, do not require prior chemotherapy for metastatic disease.
boolean
C0392920 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0278493 (UMLS CUI [1,3])
C0392920 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
C0678222 (UMLS CUI [2,3])
C3258246 (UMLS CUI [2,4])
C0085533 (UMLS CUI [3,1])
C0205197 (UMLS CUI [3,2])
C0277556 (UMLS CUI [4])
C0282564 (UMLS CUI [5])
C0215136 (UMLS CUI [6])
Measurable Disease Linear
Item
unidimensionally measurable dz (by recist)
boolean
C1513041 (UMLS CUI [1,1])
C0205132 (UMLS CUI [1,2])
Age
Item
at least 18 yrs of age
boolean
C0001779 (UMLS CUI [1])
SWOG performance status
Item
swog ps 0-2
boolean
C1519429 (UMLS CUI [1,1])
C1518965 (UMLS CUI [1,2])
Absolute neutrophil count | Platelet Count measurement | Hemoglobin measurement
Item
agc greater than or equal to 1.5; platelets greater than or equal to 100,000; hgb greater than or equal to 8.0
boolean
C0948762 (UMLS CUI [1])
C0032181 (UMLS CUI [2])
C0518015 (UMLS CUI [3])
Serum total bilirubin measurement | Aspartate aminotransferase measurement | Alanine aminotransferase measurement | Alkaline phosphatase measurement
Item
total bilirubin less than or equal to 2 x uln; sgot and/or sgpt and alk phos up to 2.5 x uln
boolean
C1278039 (UMLS CUI [1])
C0201899 (UMLS CUI [2])
C0201836 (UMLS CUI [3])
C0201850 (UMLS CUI [4])
Creatinine measurement, serum
Item
creatinine less than or equal to 2.0
boolean
C0201976 (UMLS CUI [1])
Toxic effect Secondary to Therapeutic procedure | Patient Recovered
Item
fully recovered from acute toxicities secondary to prior tx
boolean
C0600688 (UMLS CUI [1,1])
C0175668 (UMLS CUI [1,2])
C0087111 (UMLS CUI [1,3])
C0030705 (UMLS CUI [2,1])
C0521108 (UMLS CUI [2,2])
Informed Consent
Item
signed informed consent (including hipaa authorization)
boolean
C0021430 (UMLS CUI [1])
Peripheral Neuropathy CTCAE Grades
Item
peripheral neuropathy grade 0-1
boolean
C0031117 (UMLS CUI [1,1])
C1516728 (UMLS CUI [1,2])
gemcitabine | oxaliplatin | Cisplatin Completed | Carboplatin Completed
Item
prior tx with gemcitabine or oxaliplatin. prior tx with cisplatin or carboplatin allowed if completed >12 mos prior to enrollment.
boolean
C0045093 (UMLS CUI [1])
C0069717 (UMLS CUI [2])
C0008838 (UMLS CUI [3,1])
C0205197 (UMLS CUI [3,2])
C0079083 (UMLS CUI [4,1])
C0205197 (UMLS CUI [4,2])
Condition Excludes Therapeutic procedure
Item
underlying medical, psychiatric, or social conditions that would preclude patient from receiving tx
boolean
C0348080 (UMLS CUI [1,1])
C0332196 (UMLS CUI [1,2])
C0087111 (UMLS CUI [1,3])
Peripheral Neuropathy CTCAE Grades
Item
peripheral neuropathy greater than or equal to gr 2
boolean
C0031117 (UMLS CUI [1,1])
C1516728 (UMLS CUI [1,2])