Mantle cell lymphoma | Immunophenotyping | Cell positive for CD5 antigen | CD23 Antigen Negative | Cell positive for CD19 antigen | Cell positive for CD20 antigen | Cyclin D1 Positive | CD10 antigen Negative
Item
histologically confirmed diagnosis of mantle cell non-hodgkin's lymphoma with characteristic immunophenotypic profiles: cd5(+),cd23(-), cd19(+) or cd20(+), cyclin d1(+), and cd10(-)
boolean
C0334634 (UMLS CUI [1])
C0079611 (UMLS CUI [2])
C0882892 (UMLS CUI [3])
C0123242 (UMLS CUI [4,1])
C1513916 (UMLS CUI [4,2])
C0882808 (UMLS CUI [5])
C0882818 (UMLS CUI [6])
C0174680 (UMLS CUI [7,1])
C1514241 (UMLS CUI [7,2])
C0025250 (UMLS CUI [8,1])
C1513916 (UMLS CUI [8,2])
Chemotherapy | Persistent Disease | Recurrent disease
Item
patient has persistent / recurrent disease after standard chemotherapy
boolean
C0392920 (UMLS CUI [1])
C2983415 (UMLS CUI [2])
C0277556 (UMLS CUI [3])
Pharmaceutical Preparations | Investigational New Drugs
Item
patient has not received either standard or investigational drugs within the last 3 weeks
boolean
C0013227 (UMLS CUI [1])
C0013230 (UMLS CUI [2])
Tumor tissue Frozen Available | Prior Therapy Completed | Biopsy second
Item
available frozen tumor tissue obtained since completion of last prior therapy (rebiopsy if needed)
boolean
C0475358 (UMLS CUI [1,1])
C0016701 (UMLS CUI [1,2])
C0470187 (UMLS CUI [1,3])
C1514463 (UMLS CUI [2,1])
C0205197 (UMLS CUI [2,2])
C0005558 (UMLS CUI [3,1])
C0205436 (UMLS CUI [3,2])
Measurable Disease | Tumor Mass Size Linear
Item
patient has measurable disease as defined by a tumor mass > 1.5 cm in one dimension
boolean
C1513041 (UMLS CUI [1])
C3273930 (UMLS CUI [2,1])
C0475440 (UMLS CUI [2,2])
C0205132 (UMLS CUI [2,3])
Age
Item
age > 18 years
boolean
C0001779 (UMLS CUI [1])
Absolute neutrophil count
Item
absolute granulocyte count > 1000 cells/mm3
boolean
C0948762 (UMLS CUI [1])
Platelet Count measurement
Item
platelet count > 50,000 cells/mm3
boolean
C0032181 (UMLS CUI [1])
Creatinine measurement, serum
Item
creatinine < 2.0 x uln
boolean
C0201976 (UMLS CUI [1])
Serum total bilirubin measurement
Item
total bilirubin < 2.0 x uln
boolean
C1278039 (UMLS CUI [1])
Karnofsky Performance Status
Item
patient has kps > 50%
boolean
C0206065 (UMLS CUI [1])
Fertility Contraceptive methods
Item
patient agrees to use birth control if of reproductive potential
boolean
C0015895 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Lymphoma CNS involvement
Item
known central nervous system (cns) involvement by lymphoma
boolean
C0024299 (UMLS CUI [1,1])
C0449389 (UMLS CUI [1,2])
HIV
Item
known hiv disease
boolean
C0019682 (UMLS CUI [1])
Peripheral Neuropathy | CTCAE Grades
Item
known peripheral neuropathy > grade 2
boolean
C0031117 (UMLS CUI [1])
C1516728 (UMLS CUI [2])
Pregnancy | Breast Feeding
Item
patient is pregnant or nursing
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
major surgery
Item
patient has had major surgery within the last 3 weeks
boolean
C0679637 (UMLS CUI [1])
Investigational New Drugs
Item
patient is receiving other investigational drugs
boolean
C0013230 (UMLS CUI [1])