Non-Small Cell Lung Carcinoma
Item
1. histologically/cytologically documented non small cell lung carcinoma.
boolean
C0007131 (UMLS CUI [1])
TNM clinical staging | Indication Operative Surgical Procedures | Indication Therapeutic radiology procedure | Indication Therapeutic radiology procedure In addition to Chemotherapy | Palliative radiotherapy
Item
2. stages iiib and iv disease, not a candidate for definitive treatment with surgery, radiation or radiation plus chemotherapy. (palliative radiotherapy will be allowed).
boolean
C3258246 (UMLS CUI [1])
C3146298 (UMLS CUI [2,1])
C0543467 (UMLS CUI [2,2])
C3146298 (UMLS CUI [3,1])
C1522449 (UMLS CUI [3,2])
C3146298 (UMLS CUI [4,1])
C1522449 (UMLS CUI [4,2])
C0332287 (UMLS CUI [4,3])
C0392920 (UMLS CUI [4,4])
C0475092 (UMLS CUI [5])
Age
Item
3. age ≥ 18, < 75 years.
boolean
C0001779 (UMLS CUI [1])
ECOG performance status
Item
4. ecog performance status 2
boolean
C1520224 (UMLS CUI [1])
Mental disorder Serious
Item
5. no serious concomitant psychiatric illness.
boolean
C0004936 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
Informed Consent
Item
6. informed consent.
boolean
C0021430 (UMLS CUI [1])
Measurable Disease | Evaluable Disease | Physical Examination | X-Ray Computed Tomography | Plain chest X-ray | Ultrasonography | Magnetic Resonance Imaging
Item
7. presence of measurable or evaluable disease on physical examination, ct scan, chest x-ray, ultrasound or mri scan.
boolean
C1513041 (UMLS CUI [1])
C1516986 (UMLS CUI [2])
C0031809 (UMLS CUI [3])
C0040405 (UMLS CUI [4])
C0039985 (UMLS CUI [5])
C0041618 (UMLS CUI [6])
C0024485 (UMLS CUI [7])
Prior Chemotherapy Non-Small Cell Lung Carcinoma
Item
1 ) previous chemotherapy for nsclc.
boolean
C1514457 (UMLS CUI [1,1])
C0007131 (UMLS CUI [1,2])
CNS metastases
Item
2) known cns metastases at time of registration.
boolean
C0686377 (UMLS CUI [1])
Laboratory Results
Item
3) laboratory values obtained <28 days prior to entry
boolean
C1254595 (UMLS CUI [1])
Absolute neutrophil count | Platelet Count measurement | Hemoglobin | Serum total bilirubin measurement | Aspartate aminotransferase measurement | Creatinine measurement, serum
Item
anc <1.5 x 109 /l plt <100 x 109 /l hgb<100 g/l total bili >1.5 x unl (upper normal limit) alk po4 >3 x unl ast >3x unl cr >1.5 x unl.
boolean
C0948762 (UMLS CUI [1])
C0032181 (UMLS CUI [2])
C0019046 (UMLS CUI [3])
C1278039 (UMLS CUI [4])
C0201899 (UMLS CUI [5])
C0201976 (UMLS CUI [6])
Diabetic - poor control | Cardiovascular Disease | Communicable Disease Serious | Disease At risk Study Subject Participation Status
Item
4) uncontrolled diabetes mellitus, cardiovascular disease, active serious infection or other disease which in the opinion of treating physician, would make this protocol unreasonably hazardous for the patient.
boolean
C0421258 (UMLS CUI [1])
C0007222 (UMLS CUI [2])
C0009450 (UMLS CUI [3,1])
C0205404 (UMLS CUI [3,2])
C0012634 (UMLS CUI [4,1])
C1444641 (UMLS CUI [4,2])
C2348568 (UMLS CUI [4,3])
HIV Seropositivity
Item
5) known hiv positive.
boolean
C0019699 (UMLS CUI [1])
Palliative radiotherapy Measurable Disease Area
Item
6) palliative radiotherapy to only area of measurable disease.
boolean
C0475092 (UMLS CUI [1,1])
C1513041 (UMLS CUI [1,2])
C0205146 (UMLS CUI [1,3])
Malignant Neoplasms | Basal cell carcinoma Treated | Squamous cell carcinoma of skin Treated | Carcinoma in Situ Treated
Item
7) prior malignancy, except for adequately treated basal cell or squamous cell skin cancer, adequately treated non invasive carcinomas, or other cancer from which the patient has been disease free for at least five years.
boolean
C0006826 (UMLS CUI [1])
C0007117 (UMLS CUI [2,1])
C1522326 (UMLS CUI [2,2])
C0553723 (UMLS CUI [3,1])
C1522326 (UMLS CUI [3,2])
C0007099 (UMLS CUI [4,1])
C1522326 (UMLS CUI [4,2])
Pregnancy | Breast Feeding | Childbearing Potential Contraceptive methods Unwilling | Female Condoms | Vaginal contraceptive diaphragm | Contraceptives, Oral | Contraceptive injection | Intrauterine Devices | Sexual Abstinence | Female Sterilization
Item
8) pregnant or nursing women. men or women of childbearing potential who are unwilling to employ adequate contraception (condoms, diaphragm, birth control pills, injections, iud, abstinence, surgical sterilization etc).
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C3831118 (UMLS CUI [3,1])
C0700589 (UMLS CUI [3,2])
C0558080 (UMLS CUI [3,3])
C0221829 (UMLS CUI [4])
C0042241 (UMLS CUI [5])
C0009905 (UMLS CUI [6])
C1656586 (UMLS CUI [7])
C0021900 (UMLS CUI [8])
C0036899 (UMLS CUI [9])
C0015787 (UMLS CUI [10])